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Protides of the Biological Fluids contains the proceedings of the 26th Colloquium in 1978. Two topics are highlighted, the first one being the immune complexes and the second one being the cytoskeletal proteins. This book is organized into three sections, namely, Immune Complexes, Cytoskeletal Proteins, and Techniques. The Immune Complexes section states the biochemical problems and answers some intriguing clinical problems in this field. This section details the theory of the antigen/antibody reaction, the isolation of complexes, and the nature of the antigen. The Cytoskeletal Proteins section discusses the theoretical aspect of cell structure. The last section describes the assay methods and individual protein assays.
Language
Place of publication
Saint Louis
United Kingdom
ISBN-13
978-1-4831-5802-0 (9781483158020)
Schweitzer Classification
ContentsPrefaceAcknowledgmentsThe Seventh Arne Tiselius Memorial LectureAre Circulating Immune Complexes The Key To Immunopathology?Section A. Immune ComplexesA.1. Detection Methods and ReagentsPitfalls in the Use of Biologic Reagents For the Detection of Immune ComplexesPreparation of Stabilized Human IgG Aggregates of Known Size and Their Reactivity in Immune Complex Assays Automated Determination of Circulating Immune Complexes by Pacia A Semi-Automated System Permitting Analysis of Immune Complex Components A New Solid Phase Assay System For Immune Complexes Using Fc-Fragments of Human IgG (Spaif) The Use of Bovine Conglutinin As A Reagent For Detecting Immune Complexes Detection of Circulating Immune Complexes by Radioimmunoassay with Monoclonal Rheumatoid Factor: Comparison with Clq Binding and Raji Cell Radioassays in Cancer Rheumatoid Factor Radioimmunoassay For Immune Complexes Detection of Immune Complexes in Human Renal Transplantation by Using Anti-Antibody Measurements of Immune Complex Formation by Difference Turbidity A Titration Method For Rf and Immune ComplexesA.2. Theory of Antigen-Antibody ReactionAntibody Structures and Effector Functions: Immunoglobulin Carbohydrates RevisitedThe Alternative Pathway of Complement Activation: Initiation, Amplification and Control Functional Differentiation of Immunoglobulin G The Precipitin Reaction: The Importance of The Fc-Portion of IgG Calculation of Immune Complex Distributions Computer Modeling of Precipitin Reactions Modification of The Interaction Between Platelets and Immune Complexes by Cl Subcomponents (First Component of Complement) Light Scattering by Growing Antigen-Antibody Complexes A.3. Isolation of Immune ComplexesImmunologie Properties of Aggregated Human IgG: Column Fractionation of Thermal Aggregates Comparison of Raji Cells and Protein A-Sepharose For Isolation of Soluble Immune Complexes From Serum Isolation of Soluble Immune Complexes by Affinity Chromatography Using Staphylococcal Protein-A Sepharose As Substrate Purification of Soluble Immune Complexes From Serum Using Solid-Phase Conglutinin and Clq A.4. Nature of Antigen in Immune ComplexesAre Immune Complexes Immunoglobulin Aggregates?A Multi-Faceted Approach To Characterization and Isolation of Immune ComplexesMilk Precipitins and Circulating Immune Complexes in Selective IgG Deficiency Soluble Immune Complexes in Subjects with Selective Iga Deficiency Immunoglobulin-Alkaline Phosphatase Complexes in Human Serum A.5. Fate of Immune ComplexesTransport of Immune Complexes To Germinal CentersStructural Determinants For the Circulating Life-Times of Immunoglobulins and Immune ComplexesClearance of Soluble Immune Complexes and AggregatesA.6. Immune Complexes in ArthritisAnalysis of Immune Complexes in Rheumatoid Arthritis Circulating Immune Complexes in Ankylosing Spondylitis Clq Reactive Immune Complexes in Sjogren's Syndrome Immune Complexes in Rheumatoid Arthritis : Correlations with Clinical Features and Effects of Gold Thrombocyte Aggregation by Sera and Antiglobulin Complexes FromPatients with Rheumatoid Arthritis A.7. Immune Complexes in Viral, Bacterial, Parasitic InfectionsA.7.1. Viral InfectionsA.7.2. Bacterial InfectionsA.7.3. Parasitic InfectionsA.8. Immune Complexes in Systemic Lupus (SLE)Activity of Systemic Lupus Erythematosus (SLE) Followed by Circulating Immune Complexes The Heterogeneity of Immune Complexes in Disease The Occurrence and Significance of Circulating Anti-ds-DNA And Free DNA in SLE Detection of Immune Complexes in Connective Tissue Diseases: A Comparison of Three Radioassays The Occurrence of Immune Complexes in Patients with Multiple Sclerosis A.9. Immune Complexes in NephritisImmune Complexes in Human Glomerulonephritis.