Protides of the Biological Fluids
Proceedings of the Thirty-Fifth Colloquium, 1987
Published on 2. October 2013
556 pages
978-1-4831-4838-0 (ISBN)
Description
Protides of the Biological Fluids examines protides of the biological fluids and covers topics ranging from the use of DNA probes to diagnose inherited diseases and receptors to the conformation and function of biologically active peptides. This text has 115 chapters and begins by demonstrating the existence of gene families common to several vertebrates and which evolved by intragenic duplication. The chapters that follow focus on the use of DNA probes in the analysis of inherited disorders such as thalassemia and hemophilia. The reader is then introduced to receptors, especially for peptides. Receptors on circulating cells, hormone receptors, receptors involved in cancer, and immunoglobulin receptors are explored. The section on the conformation and function of biologically active peptides considers the methods including spectroscopic methods, crystallography, and theoretical conformational analysis. In particular, the use of synchrotron X-radiation in biological crystallography and of 2D NMR spectroscopy in the identification of folded structures in immunogenic peptides is highlighted. This book will be of value to biologists and biochemists.
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10/1987
Elsevier
€193.13
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Content
PrefaceAcknowledgmentsThe Sixteenth Arne Tiselius Memorial Lecture Expression of Genes Encoding the Vitamin D Binding Protein and TransferrinSection A. DNA Probes For Inherited Diseases A.1. Thalassemia Diagnosis of Thalassemia by DNA Analysis A.2. Haemophilia and X-Linked Diseases First Trimester Prenatal Diagnosis of Hemophilia A by Combined Use of DNA Probes Carrier Detection and Genetic Counselling in Hemophilia Using DNA Probes The Identification of Haemophilia B Mutations Gene Defects in Haemophilia A and B Carrier Detection Using DNA Analysis in French Families of Haemophilia A and B Studies on the Molecular Basis of Steroid Sulphatase Deficiency in Man Mitotic-Origin of a Duchenne Muscular Dystrophy Mutation A.3. Unknown Genes Progress Towards Cloning of the Cystic Fibrosis Gene-Identification of New DNA Markers in the 7Q31 Region DNA Marker Analysis of Danish Polycystic Kidney Disease Families Information Given by the 3' HVR a-Globin Marker in Ten French Families with Adult Polycystic Kidney Disease Use of a Genetic Marker for the Diagnosis of Adult Polycystic Kidney Disease in Northern Italy Construction of Lambda gt 11 cDNA Libraries from Post-Mortem Human Brains Genetic Analysis of Human T-Cell Antigens. I. Cytogenetic and Phenotypic Characterization of Interspecies T-Cell Lines Genetic Analysis of Human T-Cell Antigens. II. Mapping of the Human Chromosomes Involved in the Expression of T10 T-Cell Antigen A.4. Multifactorial Diseases Genetic Approach to the Study of Multifactorial Diseases Restriction Fragment Length Polymorphisms in the Apolipoprotein E-C1-C2 Gene Cluster: Association with Familial Dysbetalipoproteinemia The Involvement of Apolipoprotein B Gene Variants in the Determination of Serum Cholesterol Levels The Relevance of the Use of Synthetic Oligonucleotides for Apolipoprotein E (apoE) Mutants for Clinical Diagnosis of Hyperlipoproteinemia Type III DNA Markers Linked to Diabetes HLA Class II Region a Chain Polymorphism and the Genetic Susceptibility to Insulin Dependent (Type 1) Diabetes Mellitus and Coeliac Disease A.5. Other Proteins and Amino-Acids Correlation Between Polymorphic DNA Haplotypes at the Phenylalanine Hydroxylase Locus and Clinical Phenotypes of Phenylketonuria Genetic Variants of Serum Albumin and Polymorphism of the Albumin Gene Identification of Carriers of Mutant Prealbumin Gene Associated with Familial Amyloidotic Polyneuropathy Type I: Study of One Portuguese Pedigree Synthesis of Serum Amyloid A by Murine Hepatocytes and of Amyloid-Related Protein(s) by Murine Peritoneal Macrophages Unique DNA Polymorphisms Associated with the Alpha1-Antitrypsin (PI) Z Deficiency Allele: Application to Prenatal Diagnosis High Frequency of Arginine 47 Mutation in Antithrombin III Hereditary Deficiencies Affecting the Heparin Binding Site Studies of DNA Polymorphisms in Collagen Genes in Health and Disease Isolation and Characterization of a cDNA Clone for Human Alpha2-HS GlycoproteinSection B. Receptors B.1.
