
General and Synthetic Methods
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Content
- General And Synthetic Methods
- Contents
- Chapter 1 Saturated and Unsaturated Acyclic Hydrocarbons
- 1 Introduction
- 2 Saturated Hydrocarbons
- 3 Olefinic Hydrocarbons
- 4 Conjugated 1,3-Dienes
- 5 1,4- and 1,5-Dienes and Polyenes
- 6 Allenes and Cumulenes
- 7 Acetylenic Hydrocarbons
- 8 Conjugated Enynes and Miscellaneous Mixed Unsaturated Moieties
- Chapter 2 Aldehydes and Ketones
- 1 Preparations of Aldehydes and Ketones
- From Alcohols and Derivatives
- From Carboxylic Acids and Derivatives
- Transposition of the Carbonyl Group
- Sila-, Thio-, and Seleno-carbonyl Compounds
- Dicarbonyl Compounds
- Cyclic Ketones
- Other Preparations
- 2 Reactions and Condensations
- Alkylation
- Aldol Reactions
- Reduction
- General Reactions
- 3 Preparations of Unsaturated Aldehydes and Ketones
- aß-Unsaturated Aldehydes and Ketones
- Other Unsaturated Aldehydes and Ketones
- Unsaturated Ring Ketones
- 4 Reactions of aß-Unsaturated Aldehydes and Ketones
- Reduction
- Alkylation
- Conjugate Addition
- General Reactions
- 5 Protection of Aldehydes and Ketones
- 6 Halogeno-derivatives
- Chapter 3 Carboxylic Acids and Derivatives
- 1 Introduction
- 2 Carboxylic Acids
- General Synthesis
- Diacids
- Hydroxy-acids
- Unsaturated Acids
- Anhydrides
- Decarboxylation
- Protection and Deprotection
- 3 Lactones
- a- and ß-Lactones
- Butyrolactones
- Butenolides
- a-Methylenebutyrolactones
- Valerolactones
- Coumarins, Isocoumarins, and a -Pyrones
- 4 Macrolides
- 5 Esters
- Esterification
- General Synthesis
- Diesters
- Hydroxy-esters
- Unsaturated Esters
- Keto-esters
- 6 Carboxylic Acid Amides
- Synthesis
- Reactions
- 7 Amino-acids
- Synthesis and Reactions
- Protection and Deprotection
- Chapter 4 Alcohols, Halogeno-compounds, and Ethers
- 1 Alcohols
- Preparation
- Carbonyl Group Reduction
- Allylic Alcohols
- Homoallylic Alcohols
- Reactions
- Protection
- 1,2-, 1,3-, and 1,4-Diols
- 2 Halogeno-compounds
- Preparation
- Reactions
- 3 Ethers
- Preparation
- Reactions
- 4 Thiols and Thioethers
- Preparation
- Reactions
- 5 Macrocyclic 'Crown' Polyethers and Related Compounds
- Synthesis
- Complexation
- Applications to Phase-transfer Methods
- Chapter 5 Amines, Nitriles, and Other Nitrogen-containing Functional Groups
- 1 Amines
- Preparation
- Protection
- Reactions
- Enamines
- Hydroxylamines dnd Nitramines
- 2 Nitriles
- Preparations
- Reactions
- Isocyanides
- 3 Azides, Isocyanates, and Isothiocyanates
- 4 Nitro- and Nitroso-alkanes
- Chapter 6 Organometallics in Synthesis
- Part I The Transition Elements
- 1 Introduction
- 2 Hydrogenation
- 3 Oxidation
- 4 Isomerization
- 5 Carbonylation
- 6 Carbon-Carbon Bond Formation
- Cyclization
- Addition to Olefins
- Organo-copper Reagents
- Miscellaneous Alkylations
- 7 Synthesis of Nitrogen Heterocyclic Compounds
- 8 Reactions of Co-ordinated Ligands
- Part II Main Group Elements
- 1 Introduction
- 2 Group I
- Lithium
- Acyl-lithiums and their Equivalents
- Lithium Carbenoids
- Mono-a-heteroatom-substituted Organolithium Reagents
- Alkenyl- and Alkynyl-lithiums
- Aryl-lithiums
- Miscellaneous
- Sodium, Potassium, Rubidium, and Caesium
- 3 Group II
- Magnesium
- Zinc, Cadmium, and Mercury
- 4 Group III
- Boron
- Preparation of Organoboranes
- Reductions using Organoboron Compounds
- Applications of Organoborates
- Applications of Organoboranes
- Aluminium and Thallium
- 5 Group IV
- Silicon
- Preparation of Organosilicon Compounds
- C-C Bond Formation using Organosilanes
- Miscellaneous
- Tin
- 6 Groups V and VI
- Phosphorus
- Arsenic
- Sulphur
- Desulphurizations
- a -Chloro Organosulphur Compounds
- Miscellaneous
- Selenium
- Chapter 7 Saturated Carbocyclic Ring Synthesis
- 1 Introduction
- 2 Three-membered Rings
- General Methods
- Natural Cyclopropanes
- 3 Four-membered Rings
- 4 Five-membered Rings
- General Methods
- Prostaglandins
- Rethrolones and Related Compounds
- Fused Five-membered Rings
- 5 Six-membered Rings
- Diels-Alder Cycloadditions
- Robinson and Related Annelations
- Other Six-ring Syntheses
- 6 Polyene Cyclizations and Polycyclic Synthesis
- 7 Seven-membered Rings
- 8 Medium-sized Rings
- 9 Large Rings
- 10 Spiro-ring Annelations
- 11 Miscellaneous Methods
- Chapter 8 Strategy and Design in Synthesis
- 1 Introduction
- 2 General Papers
- 3 Selected Total and Partial Syfftheses
- (±)-Bakkenolide-A
- (±)-Clavulanic Acid
- Disodium Prephenate
- Indigo
- Macrolides
- (±)-Steganacin
- Others
- 4 Prostaglandins and Related Molecules
- 5 Introduction and Interchange of Functional Groups
- General
- Umpolung
- Multi-phase Systems
- Remote or Inactive Positions
- 6 The Carbon Skeleton
- 7 Syntheses of Optically Active Materials
- The Use of Optically Active Starting Materials
- Asymmetric Syntheses
- Resolution
- Reviews on General Synthetic Methods
- 1 Olefinic Hydrocarbons
- 2 Aldehydes and Ketones
- 3 Lactones and Macrolides
- 4 Peptides
- 5 Halogeno-compounds
- 6 Ethers
- 7 Nitrogen-containing Functional Groups
- 8 Organometallics
- General
- Magnesium
- Boron
- Phosphorus
- Sulphur
- Transition Elements
- 9 Carbocycles
- 10 Heterocycles
- 11 Oxidation and Reduction
- 12 Natural Product Synthesis
- 13 Design of Synthesis
- General
- Computer Assisted
- 14 General
- 15 Miscellaneous
- Author Index
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