Lipoic Acid
Energy Production, Antioxidant Activity and Health Effects
Published on 17. March 2008
556 pages
978-1-4200-4539-0 (ISBN)
Description
The recognition of oxidative stress as a major factor in health, aging, and disease has led to a surge in research aimed at uncovering effective countermeasures in the form of antioxidants. Unique in its two-fold protective function, alpha-lipoic acid has drawn unprecedented interest as a coenzyme in mitochondrial energy metabolism and as an antiox
More details
Language
English
Place of publication
Baton Rouge
United States
Publishing group
Taylor & Francis Inc
Target group
Professional and scholarly
Biomedical researchers, including biochemists and physiologists, and clinicians, especially those focusing on diabetes, diet, and nutrition.
Illustrations
145 s/w Abbildungen, 18 s/w Tabellen
145 b/w images and 18 tables
File size
8,12 MB
ISBN-13
978-1-4200-4539-0 (9781420045390)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Mulchand S. Patel | Lester Packer
Lipoic Acid
Energy Production, Antioxidant Activity and Health Effects
Book
09/2019
1st Edition
CRC Press
€97.90
Shipment within 15-20 days
Mulchand S. Patel | Lester Packer
Lipoic Acid
Energy Production, Antioxidant Activity and Health Effects
Book
03/2008
1st Edition
CRC Press
€314.90
Shipment within 15-20 days
Persons
Mulchand S. Patel, Lester Packer
Content
Discovery molecular structure,A Trail of Research on Lipoic Acid, Lipoic Acid Biosynthesis, The Search for Potent ?-lipoic Acid Derivatives: Chemical and Pharmacological Aspects, Novel Indole Lipoic Acid Derivatives: Synthesis and their Antioxidant Effects, Metabolic aspects, The ?-keto Acid Dehydrogenase Complexes and Glycine Cleavage System: Their Involvement in Pathways of Carbohydrate, Protein, and Fat Metabolism, Pyruvate Dehydrogenase Complex Regulation and Lipoic Acid, Role of Lipoyl Domains in the Function and Regulation of the Mammalian Pyruvate Dehydrogenase Complex, Inactivation and Inhibition of ?-ketoglutarate Dehydrogenase: Oxidative Modulation of Lipoic Acid, Lipoate-Protein Ligase A: Structure and Function, A Review of the Stability & Preliminary Evaluation of the Plasma Pharmacokinetics of R-lipoic acid & R-Dihydrolipoic Acid Dosage Forms in Human Plasma from Healthy Volunteers, The Pharmacokinetics, Metabolism and Renal Excretion of ?-lipoic Acid and its Main Metabolites in Humans, Modulation of Cellular Redox and Metabolic Status by Lipoic Acid, The Redoxin Connection of Lipoic Acid, Lipoic Acid as an Inducer of Phase II Detoxification Enzymes through Activation of Nrf2-dependent Gene Expression, Clinical aspects, Deficiency Disorders of Components of the PDH Complex: E2, BP & E3 Deficiencies, The Relationship between Primary Biliary Cirrhosis and Lipoic Acid, Effects of Lipoic Acid on Insulin Action in Animal Models of Insulin Resistance, Activation of Cytoprotective Signaling Pathways by Alpha-Lipoic Acid, Selenotrisulfide Derivatives of Alpha Lipoic Acid: Potential Use as a Novel Topical Antioxidant, Alpha-Lipoic Acid: A Potent Mitochondrial Nutrient for Improving Memory Deficit, Oxidative Stress, and Mitochondrial Dysfunction, Effects of Alpha-Lipoic Acid on AMP-Activated Kinase in Different Tissues: Therapeutic Implications for the Metabolic Syndrome
