
Neuroendocrine Tumors: A Multidisciplinary Approach
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Content
- Cover
- Front Matter
- Contents
- Preface
- General Design of the Current Volume
- References
- Epidemiology of Neuroendocrine Tumors
- Abstract
- Histologic Classification of Neuroendocrine Tumors
- Coding Systems of Neuroendocrine Tumors
- Anatomic Sites of Neuroendocrine Neoplasia
- Limitations in the Interpretation of Data on Neuroendocrine Neoplasia Epidemiology
- Sources of Information on Neuroendocrine Tumor Epidemiology
- Stomach
- Small Intestine
- Pancreas
- Colorectum
- Colon (Rectum Excluded)
- Rectum
- Appendix
- Bronchopulmonary Tree
- References
- Biochemical Testing in Patients with Neuroendocrine Tumors
- Abstract
- General Markers
- Specific Markers
- Tumor Markers in Neuroendocrine Tumors
- Conclusion
- References
- Clinical Syndromes Related to Gastrointestinal Neuroendocrine Neoplasms
- Abstract
- Clinical Syndromes Secondary to Gastrointestinal Neuroendocrine Neoplasms
- Clinical Syndromes of Gastrointestinal Neuroendocrine Neoplasms According to the Tissue of Origin
- Treatment of the Carcinoid Syndrome and Related Syndromes
- Clinical Syndromes of Gastrointestinal Neuroendocrine Neoplasms According to the Tissue of Origin
- Treatment of the Carcinoid Syndrome and Related Syndromes
- Paraneoplastic Syndromes Secondary to Neuroendocrine Tumors
- Treatment of Clinical Syndromes Related to Pancreatic Neuroendocrine Neoplasms
- Conclusion
- References
- Radiological Imaging: Computed Tomography, Magnetic Resonance Imaging and Ultrasonography
- Abstract
- Imaging Techniques
- Imaging Findings
- Image Surveillance and Monitoring of Neuroendocrine Tumor Therapy
- References
- Nuclear Medicine Imaging of Neuroendocrine Tumors
- Abstract
- Imaging of Neuroendocrine Tumors
- Somatostatin Receptor-Based Imaging
- Somatostatin Receptor PET/CT
- Other Imaging Modalities
- Imaging Response after Therapy
- Conclusion
- References
- Endoscopy and Endoscopic Ultrasound in Assessing and Managing Neuroendocrine Neoplasms
- Abstract
- Gastrointestinal Neuroendocrine Neoplasms
- Pancreatic Neuroendocrine Neoplasms
- EUS-Guided Fine-Needle Aspiration and Biopsy, and Newer Techniques
- References
- Pathology: Classification and Immunoprofile
- Abstract
- Classification of Neuroendocrine Neoplasms in the Gastroenteropancreatic System
- Classification in the Lung, Thymus and Genitourinary Tract
- Immunohistochemistry
- Important Organ-Specific Features
- References
- Genetics and Epigenetics of Pancreatic Neuroendocrine Tumors and Pulmonary Carcinoids
- Abstract
- Inherited Neuroendocrine Tumor Predisposition Syndromes
- Genetic and Epigenetic Studies in Sporadic Neuroendocrine Tumors
- Therapeutic Consequences of Genetic and Epigenetic Studies in Neuroendocrine Tumors
- References
- Pancreatic Surgery
- Abstract
- Surgical Approaches for Primary Tumor with Clinical Endocrine Syndrome
- Localized Nonfunctioning Pancreatic Neuroendocrine Tumors
- Locally Advanced Pancreatic Neuroendocrine Tumors
- Metastatic Disease
- Surgical Techniques
- Open or Laparoscopic Approach?
- References
- Gastrointestinal Surgery of Neuroendocrine Neoplasms
- Abstract
- Esophageal Neuroendocrine Neoplasms
- Gastric Neuroendocrine Neoplasms
- Duodenal Neuroendocrine Neoplasms
- Pancreatic Neuroendocrine Neoplasms
- Small Intestinal Neuroendocrine Neoplasms
- Appendiceal Neuroendocrine Neoplasms
- Colonic Neuroendocrine Neoplasms
- Rectal Neuroendocrine Neoplasms
- Neuroendocrine Carcinomas
- Mixed Adenocarcinomas and Neuroendocrine Carcinomas
- Neuroendocrine Liver Metastases
- Peritoneal Metastases
- Follow-Up
- Conclusion
- References
- Transplantation and Debulking Procedures for Neuroendocrine Tumors
- Abstract
- Debulking
- Transplantation
- References
- A 25-Year Experience of Gastroenteropancreatic Neuroendocrine Tumors and Somatostatin (Congeners) Analogs: From Symptom Control to Antineoplastic Therapy
- Abstract
- Carcinoid Tumors Subjects
- Pancreatic Neuroendocrine Tumor Subjects
- Somatostatin Congener Depot Formulations
- Future Considerations
- References
- Medical Therapy of Pulmonary Neuroendocrine Neoplasms: Targeted,Symptomatic and Chemotherapy
- Abstract
- Control of Associated (Neuro) Endocrine Hypersecretions
- Control of Tumor Growth in the Metastatic Setting or in Patients Not Candidates for Surgery
- Somatostatin Analogs
- Target Therapies
- Chemotherapy
- Conclusions
- References
- Peptide Receptor Radionuclide Therapy of Neuroendocrine Tumors
- Abstract
- Historical Overview
- Technique
- Peptide Receptor Radionuclide Therapy Results
- References
- Hormone and Receptor Candidates for Target and Biotherapy of Neuroendocrine Tumors
- Abstract
- Hormone Receptors in Neuroendocrine Tumors
- Mechanisms Influencing Treatment Response and Uptake of Radiolabeled Somatostatin Analogs
- Role of Hormone Receptors in the Diagnosis of Neuroendocrine Tumors
- Clinical Experience of Targeting Hormone Receptors in Neuroendocrine Tumors
- References
- The Role of Chemotherapy in Well-Differentiated Gastroenteropancreatic Neuroendocrine Tumors
- Abstract
- Streptozocin Combinations
- Dacarbazine and Temozolomide
- Temozolomide Combinations
- Oxaliplatin-Based Regimens
- Predictors of Response to Chemotherapy
- Choice of Chemotherapy in Intermediate- to High-Grade Tumors
- References
- Other Novel Therapies: Biomarkers, microRNAs and microRNA Inhibitors, DNA Methylation, Epigenetics, Immunotherapy and Virotherapy
- Abstract
- Novel Biomarkers
- microRNAs and microRNA Inhibitors
- Epigenetics of Neuroendocrine Tumors - DNA Methylation and Histone Modifications
- Recent Advancements in Cancer Immunotherapy
- Immune Checkpoint Antibodies
- Adoptive Transfer of Genetically Engineered T Cells
- Cancer Vaccination
- Other Forms of Immunotherapy
- Oncolytic Viruses as Immunotherapy
- Combination Treatments
- Immune Scoring of Tumors to Predict Clinical Outcome
- Future Perspectives
- References
- Author Index
- Subject Index
- Back Cover
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File format: PDF
Copy-Protection: Adobe-DRM (Digital Rights Management)
System requirements:
- Computer (Windows; MacOS X; Linux): Install the free reader Adobe Digital Editions prior to download (see eBook Help).
- Tablet/smartphone (Android; iOS): Install the free app Adobe Digital Editions or the app PocketBook before downloading (see eBook Help).
- E-reader: Bookeen, Kobo, Pocketbook, Sony, Tolino and many more (only limited: Kindle).
The file format PDF always displays a book page identically on any hardware. This makes PDF suitable for complex layouts such as those used in textbooks and reference books (images, tables, columns, footnotes). Unfortunately, on the small screens of e-readers or smartphones, PDFs are rather annoying, requiring too much scrolling.
This eBook uses Adobe-DRM, a „hard” copy protection. If the necessary requirements are not met, unfortunately you will not be able to open the eBook. You will therefore need to prepare your reading hardware before downloading.
Please note: We strongly recommend that you authorise using your personal Adobe ID after installation of any reading software.
For more information, see our eBook Help page.