Advances in Lipid Research
Published on 25. November 2014
448 pages
978-1-4832-2444-2 (ISBN)
Description
Advances in Lipid Research, Volume 5 presents information pertinent to the chemistry, biochemistry, and physiology of lipids. This book discusses the metabolism of myelin lipids and explains the factors affecting brain cholesterol. Organized into nine chapters, this volume begins with an overview of the biosynthesis of fatty acids. This text then discusses the physiology of adipose tissue in which aspects of adipose tissue physiology of a number of animal species are compared. Other chapters consider the physiological, biochemical, and morphological changes observed in ethionine-induced fatty liver. This book discusses as well the metabolism of lipids by macrophages and the relationship of this phenomenon to atherosclerosis. The final chapter deals with the phase diagrams of glyceride mixtures, a subject that is more physicochemical in nature and suggests another area of investigation to biologists. This book is a valuable resource for biologists, biochemists, neurochemists, scientists, and research workers.
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Content
List of ContributorsPrefaceContents of Previous VolumesFatty Acid Biosynthesis and the Role of the Acyl Carrier Protein I. Introduction II. Acetyl CoA Carboxylase III. Fatty Acid Synthetase IV. Acyl Carrier Protein V. Enzymes of Fatty Acid Synthesis VI. Other Reactions Involving Acyl Carrier Protein VII. Multienzyme Complex of Fatty Acid Synthesis VIII. Unsaturated Fatty Acid Biosynthesis IX. Control of Fatty Acid Biosynthesis ReferencesComparative Studies on the Physiology of Adipose Tissue I. Introduction II. Metabolic Pathways and Hormonal Responsiveness of Rat Adipose Tissue III. Adipose Tissue of the Mouse IV. Adipose Tissue of the Hamster V. Adipose Tissue of the Rabbit VI. Adipose Tissue of the Guinea Pig VII. Adipose Tissue of Man VIII. Adipose Tissue of Birds IX. Adipose Tissue of Other Species X. Discussion XI. Summary ReferencesEthionine Fatty Liver I. Introduction and General Considerations II. Characteristics of the Fatty Liver III. Mechanism of Induction-Pathogenesis ReferencesLipid Metabolism by Macrophages and its Relationship to Atherosclerosis I. Introduction II. Morphological Observations on Lipid Metabolism by Macrophages in Early Atherosclerotic Lesions III. Metabolism of Cholesterol by Macrophages IV. Esterification of Cholesterol by Macrophages V. Metabolism of Triglyceride and Fatty Acid by Macrophages VI. Synthesis of Lipid by Macrophages VII. Blood Lipophages and Atherosclerosis VIII. Other Aspects of Lipid Metabolism by Macrophages IX. Conclusions and Present Problems ReferencesDynamics of Cholesterol in Rats, Studied by the Isotopic Equilibrium Method I. Introduction II. Dynamics of Cholesterol in Adult Rats III. Dynamics of Cholesterol in Growing Rats ReferencesThe Metabolism of Myelin Lipids I. Introduction II. Preparation of Purified Myelin III. Lipid Composition and the Structure of Myelin IV. The Lipid Metabolism of Myelin V. Factors Affecting Turnover VI. Conclusion ReferencesBrain Cholesterol: The Effect of Chemical and Physical Agents I. Introduction II. Neural Composition III. Development and Aging of the Central Nervous System IV. Cholesterol Biosynthesis V. Uptake and Turnover of Cholesterol by the Brain VI. Effect of Drugs and Physical Agents on Brain Cholesterol VII. Summary ReferencesThe Analysis of Individual Molecular Species of Polar Lipids I. Introduction II. Separation of Molecular Species of Intact Polar Lipids III. Separation of Molecular Species of Chemically Modified Polar Lipids IV. Conclusion ReferencesPhase Diagrams of Triglyceride Systems Introduction I. Melting Behavior of Binary Mixtures of Simple (Mono-Acid ) Triglycerides II. Phase Diagrams of Binary Mixtures of Mixed-Acid Triglycerides III. Phase Diagrams of Ternary and Multicomponent Mixtures IV. Phase Diagrams of Mixtures Containing Partial Glycerides ReferencesAuthor IndexSubject Index
