PROG NUCLEIC ACID RES&MOLECULAR BIO V2
Academic Press
Published on 1. January 1963
345 pages
978-0-08-086290-3 (ISBN)
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PROG NUCLEIC ACID RES&MOLECULAR BIO V2
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12/1963
Academic Press
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Content
- Cover
- List of Contributors
- Preface
- Abbreviations and Symbols
- Contents
- Chapter 1. Nucleic Acids and Information Transfer
- I. A Critique of the Watson-Crick Template Mechanism
- II. A Proposed Mechanism of Information Transfer
- III. Possible Consequences of the Proposed Model
- IV. The Conserved DNA Unit in Information Transfer
- V. Regulation in Information Transfer
- References
- Chapter 2. Nuclear Ribonucleic Acid
- I. Amount and Distribution of RNA in the Cell Nucleus
- II. Physical State of the Nuclear RNA
- III. Molecular Weight Base Composition. and Physical Properties of Nuclear RNA
- IV. Kinetics of Synthesis of Nuclear RNA
- V. Metabolic Instability of RNA and the Question of Turnover
- VI. Site of Breakdown of Nuclear RNA and Nature of the Breakdown Products
- VII. Enzymes Involved in the Synthesis and Breakdown of Nuclear RNA
- VIII. Relationship between Nuclear and Cytoplasmic RNA
- IX. Nucleolar RNA
- X. Nuclear RNA and the Transfer of Information from Nucleus to Cytoplasm
- References
- Chapter 3. Plant Virus Nucleic Acids
- I. Introduction
- II. The Amount of Nucleic Acid in Plant Viruses
- III. The Position of the Nucleic Acid in Plant Viruses
- IV. The Fine Structure of Plant Virus Ribonucleic Acids
- V. Virus Ribonucleic Acids as "Messengers
- VI. Mutations in Plant Viruses
- VII. The Taxonomic Importance of Plant Virus Nucleic Acids
- VIII. The Claimed Synthesis of Infectious Tobacco Mosaic Virus RNA in Vitro
- IX. Addendum
- References
- Chapter 4. The Nuclease of Escherichia coli
- I. RNA-Specific Depolymerases
- II. DNA-Specific Depolymerases
- III. Phosphomonoesterases
- IV. Nucleosidases
- V. Deaminases.
- VI. Terminal Oxidation of Pentose Phosphates
- VII. DNA-Specsc Nucleases in Bacteriophage-Infected E. coli
- VIII. The Action of Mitomycin C
- IX. Speculations on the Role of Nucleases in the Nucleic Acid Economy of E. coli
- X. Concluding Comments
- References
- Chapter 5. Specificity of Chemical Mutagenesis
- I. Introduction
- II. Theories of Mutagenesis
- III. Data on Induced Mutation
- IV. Mechanisms of Mutagen Action
- V. Summary
- References
- Chapter 6. Column Chromatography of Oligonucleotides and Polynucleotides
- I. Chromatography of Oligonucleotides
- II. Chromatographic Separation of Nucleic Acids
- References
- Chapter 7. Mechanism of Action and Application of Azapyrimidines
- I. Introduction
- II. The Antibacterial Effect of Different Derivatives of Azapyrimidines
- III. The Mechanism of Action of the Most Important Azapyrimidines
- IV. Biological Effects of 6-Azauridine
- V. General Comments Concerning the Application of Azapyrimidines
- References
- Addendum
- Chapter 8. The Function of the Pyrimidine Base in the Ribonuclease Reaction
- I. Introduction
- II. Mechanisms of the Nonenzymatic Cleavage of 3' Ribonucleoside Di- and Triesters
- III. The Mechanism of the Enzymatic Reaction
- References
- Chapter 9. Preparation Fractionation and Properties of sRNA
- I. Introduction
- II. Amino Acid-Acceptor Activity
- III. The Preparation of Transfer RNA's from Different Organisms
- IV. The Fractionation of Transfer RNA's
- V. The Nucleotide Composition of Transfer RNA's
- VI. The Secondary Structure of sRNA's
- VII. The Nucleotide Sequences of sRNA
- VIII. The Structure and Function of Transfer RNA Molecules
- References
- Index
- Author Index
- Subject Index
