PROG NUCLEIC ACID RES&MOLECULAR BIO V1
Academic Press
Published on 1. January 1963
423 pages
978-0-08-086289-7 (ISBN)
Description
PROG NUCLEIC ACID RES&MOLECULAR BIO V1
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James Norman Davidson
Progress in Nucleic Acid Research and Molecular Biology: v. 1
Book
12/1963
Academic Press
€96.11
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Content
- Front Cover
- Progress in Nucleic Acid Research, Volume 1
- Copyright Page
- Contents
- List of Contributors
- Preface
- Abbreviations and Symbols
- Chapter 1. "Primer" in DNA Polymerase Reactions
- I. Introduction
- II. Definitions and Polymer Principles
- III. Priming Activity as a Function of Molecular Weight and State
- IV. Chemical and Physical Effects as an Aid in Elucidating Mechanism
- V. Hypothetical Mechanism for DNA Synthesis
- VI. Summary
- References
- Chapter 2. The Biosynthesis of Ribonucleic Acid in Animal Systems
- I. Introduction
- II. Systems Incorporating One or Two Ribonucleotides into Polyribonucleotides
- III. Systems Incorporating All Four Ribonucleotide Residues
- IV. Requirement for a Primer
- V. Site of RNA Biosynthesis in the Cell
- VI. Speculations as to the Significance of the Different Synthetic Pathways
- References
- Chapter 3. The Role of DNA in RNA Synthesis
- I. Introduction
- II. The in Vivo Control of RNA Synthesis by DNA
- III. The in Vitro Control of RNA Synthesis by DNA
- IV. Conclusion
- References
- Chapter 4. Polynucleotide Phosphorylase
- I. Introduction
- II. Isolation of Polynucleotide Phosphorylase
- III. The Catalytic Reaction
- IV. Reaction Mechanism
- V. Polymers
- VI. Physiological Function of Polynucleotide Phosphorylase
- References
- Chapter 5. Messenger Ribonucleic Acid
- I. Synopsis
- II. Synthesis of Template RNA
- III. Kinetics of mRNA Synthesis
- IV. In Vitro Combination of Ribosomes with Added RNA
- V. The Functioning of mRNA in Peptide Synthesis
- VI. Conclusion
- References
- Chapter 6. The Recent Excitement in the Coding Problem
- I. Introduction
- II. General Questions
- III. The Cell-Free system
- IV. Amino Acid Changes from a Single Mutation
- V. Further Experimental Evidence
- VI. Is the Code Degenerate?
- VII. Theoretical Matters
- VIII. General Observations
- Addendum
- References
- Chapter 7. Some Thoughts on the Double-Stranded Model of Deoxyribonucleic Acid
- Text
- Concluding Remarks
- References
- Chapter 8. Denaturation and Renaturation of Deoxyribonucleic Acid
- I. Properties of the Native and Denatured States of DNA
- II. Early Denaturation Studies on DNA
- III. Denaturation and Evidence for Strand Separation
- IV. General Aspects of Denaturation and Renaturation
- V. Mechanism of Renaturation
- VI. Hybrid Formation
- VII. Applications of Renaturation
- VIII. Summary
- References
- Chapter 9. Some Problems Concerning the Macromolecular Structure of Ribonucleic Acids
- I. Introduction
- II. Chain Length
- III. Chain Conformation of RNA in Solution
- IV. On Chain Conformation within Ribosomes
- V. Conclusion
- References
- Chapter 10. The Structure of DNA as Determined by X-ray Scattering Techniques
- I. Introduction
- II. X-ray Diffraction Technique
- III. The Chemical and Physicochemical Evidence
- IV. The Structure of DNA Fibers
- V. The Structure of DNA in Solution
- VI. Discussion and Conclusions
- References
- Chapter 11. Molecular Mechanisms of Radiation Effects
- I. Preface
- II. Ultraviolet Light
- III. X-rays
- IV. Conclusion
- References
- Author Index
- Subject Index
