Design of Caspase Inhibitors as Potential Clinical Agents
Published on 28. October 2008
312 pages
978-1-4200-4541-3 (ISBN)
Description
Presents the Therapeutic Potential for Caspase Inhibitors: Present and FutureCaspases represent one of the most specific protease families described to date. These extremely important enzymes are crucial to the destruction of aberrant cells - the body's self-protection mechanism for warding off the growth of abnormal cells, many of which can promot
More details
Language
English
Place of publication
Baton Rouge
United States
Publishing group
Taylor & Francis Inc
Target group
Professional and scholarly
Academic researchers in medicinal chemistry, cell biology, biochemistry, molecular biology, and pharmacology. Pharmaceutical and biotechnology researchers in inflammatory or apoptotic-related fields.
Illustrations
8-page 4-color insert, 102 s/w Abbildungen, 75 s/w Tabellen
102 b/w images and 75 tables
File size
13,14 MB
ISBN-13
978-1-4200-4541-3 (9781420045413)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Tom O'Brien | Steven D. Linton
Design of Caspase Inhibitors as Potential Clinical Agents
Book
10/2019
1st Edition
CRC Press
€79.28
Shipment within 15-20 days
Tom O'Brien | Steven D. Linton
Design of Caspase Inhibitors as Potential Clinical Agents
Book
10/2008
1st Edition
CRC Press
€327.13
Shipment within 15-20 days
Content
Mammalian Caspase Activation Pathways in Apoptosis and Inflammation. Role of Caspases in Inflammation-Driven Diseases. Role of Caspases in Apoptotic-Driven Indications. Kinetics and Catalytic Activity of Caspases. Nonpeptide Small Molecule Inhibitors of Caspases. Identification of Inflammatory Caspase Inhibitors. Identification of Apoptotic Caspase Inhibitors. Discovery of a First-in-Class Apoptotic Caspase Inhibitor. Emricasan (PF-03491390/IDN-6556). Novel Approaches to Caspase Inhibitor Discovery. Therapeutic Potential for Caspase Inhibitors: Present and Future. Index.
