Heat Shock Response
1st Edition
Published on 9. September 2022
536 pages
978-1-000-71443-2 (ISBN)
Description
This book focuses on heat shock response-an active yet transient reprogramming of cellular activities to the needs of a stress protection mechanism designed to minimize heat damage and to optimize restoration of normal cellular activities after the stress period. This work places major emphasis on the structure and possible cellular functions of heat shock proteins as well as the analysis of heat shock protein-coding genes by transfection into homologous and heterologous expression systems. It also discusses heat shock effects on all levels of gene expression, on cell ultrastructure, and metabolic activities. This unique text is a must for all those who are involved with genetics, nucleic acids research, and cancer research.
More details
Edition
1. Auflage
Language
English
Place of publication
London
United Kingdom
Publishing group
Taylor & Francis Ltd
Target group
Professional and scholarly
ISBN-13
978-1-000-71443-2 (9781000714432)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions
Lutz Nover
Heat Shock Response
Book
06/1991
1st Edition
CRC Press
€519.95
Article not available at the moment
Person
Lutz Nover
Content
INTRODUCTION: HISTORICAL ROOTS. STRESS PROTEINS and GENES. Inducers: Heat Shock and Chemical Stressors. Heat Shock Proteins. HSP-Coding Genes. The Glucose-Regulated Proteins (GRP). RNAs as Heat Shock Products. Gene Technology and Functional Analyses of hs Genes. The Heat Shock Transcription Factor. Control of HSP Synthesis. PROGRAMMING of CELLULAR ACTIVITIES. Chromatin Structure, Transcription and Pre-mRNP Processing. Synthesis and Degradation of Ribosomes. Translational Control. Modification and Degradation of Proteins. Recovery of Gene Expression. Heat Shock-Induced Changes of Cell Ultrastructure. Cell Cycle and DNA Synthesis. Intracellular Localization of Heat Shock Proteins. Induced Thermotolerance. Heat Shock Induced Developmental Effects. Hyperthermia and Virus Multiplication. Hyperthermic Treatment of Cancer.
