
Medical Image Computing and Computer-Assisted Intervention - MICCAI 2015
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The three-volume set LNCS 9349, 9350, and 9351 constitutes the refereed proceedings of the 18th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2015, held in Munich, Germany, in October 2015. Based on rigorous peer reviews, the program committee carefully selected 263 revised papers from 810 submissions for presentation in three volumes. The papers have been organized in the following topical sections: quantitative image analysis I: segmentation and measurement; computer-aided diagnosis: machine learning; computer-aided diagnosis: automation; quantitative image analysis II: classification, detection, features, and morphology; advanced MRI: diffusion, fMRI, DCE; quantitative image analysis III: motion, deformation, development and degeneration; quantitative image analysis IV: microscopy, fluorescence and histological imagery; registration: method and advanced applications; reconstruction, image formation, advanced acquisition - computational imaging; modelling and simulation for diagnosis and interventional planning; computer-assisted and image-guided interventions.
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Content
- Intro
- Preface
- Organization
- Contents - Part III
- Quantitative Image Analysis I: Segmentation and Measurement
- Deep Convolutional Encoder Networks for Multiple Sclerosis Lesion Segmentation
- 1 Introduction
- 2 Methods
- 3 Experiments and Results
- 4 Conclusions
- References
- Unsupervised Myocardial Segmentation for Cardiac MRI
- 1 Introduction
- 2 Related Work
- 3 Method
- 4 Results
- 5 Discussions and Conclusion
- References
- Multimodal Cortical Parcellation Based on Anatomical and Functional Brain Connectivity
- 1 Introduction
- 2 Materials
- 2.1 RS-fMRI Data
- 2.2 dMRI Data
- 3 Methods
- 3.1 Estimating Brain Connectivity
- 3.2 Adaptively Weighted Multimodal Connectivity Model
- 3.3 Affinity Matrix Estimation
- 4 Results and Discussion
- 4.1 Quantitative Results
- 4.2 Qualitative Results
- 5 Conclusions
- References
- Slic-Seg: Slice-by-Slice Segmentation Propagation of the Placenta in Fetal MRI Using One-Plane Scribbles and Online Learning
- 1 Introduction
- 2 Methods
- 3 Experiments and Results
- 4 Conclusion
- References
- GPSSI: Gaussian Process for Sampling Segmentations of Images
- 1 Introduction
- 2 Existing Generative Models of Segmentations
- 3 GPSSI
- 3.1 Definition
- 3.2 Efficient Sampling
- 4 Results
- 4.1 Parameter Setting
- 4.2 Segmentation Sampling
- 5 Tumor Delineation Uncertainty in Radiotherapy
- 6 Conclusion
- References
- Multi-Level Parcellation of the Cerebral Cortex Using Resting-State fMRI
- 1 Introduction
- 2 Methodology
- 2.1 Data Acquisition and Preprocessing
- 2.2 Initial Parcellation via Supervertex Clustering
- 2.3 Single-Level Parcellation via Hierarchical Clustering
- 2.4 Groupwise Parcellation via Spectral Clustering
- 3 Results
- 4 Conclusions
- References
- Interactive Multi-organ Segmentation Based on Multiple Template Deformation
- 1 Medical Motivation and Overview
- 2 Methodology
- 2.1 Multiple Implicit Template Deformation with User Constraints
- 2.2 Numerical Optimization
- 2.3 Enhancing the Framework for Local Contours Editing
- 2.4 Flexibility of the Framework
- 3 A Study for the Evaluation of the User Interactions
- 4 Conclusion
- References
- Segmentation of Infant Hippocampus Using Common Feature Representations Learned for Multimodal Longitudinal Data
- 1 Introduction
- 2 Method
- 2.1 Hierarchical Learn ning of Common Feature Representations
- 2.2 Patch-Based Label Fusion for Hippocampus Segmentation
- 3 Experimental Results
- 4 Conclusion
- References
- Measuring Cortical Neurite-Dispersion and Perfusion in Preterm-Born Adolescents Using Multi-modal MRI
- 1 Introduction
- 2 Methods
- 3 Results
- 3.1 Comparison of DWI with and without Additional T2 Imaging
- 3.2 Comparison of Quantitative Neuroimaging Parameters
- 3.3 Correlation of Diffusion MRI and Cerebral Blood Flow
- 4 Discussion
- References
- Interactive Whole-Heart Segmentation in Congenital Heart Disease
- 1 Introduction
- 2 Patch-Based Interactive Segmentation
- 3 Empirical Study: Active Learning for Reference Selection
- 4 Results
- 5 Conclusions
- References
- Automatic 3D US Brain Ventricle Segmentation in Pre-Term Neonates Using Multi-phase Geodesic Level-Sets with Shape Prior
- 1 Introduction
- 2 Method
- 3 Experiments and Results
- 4 Discussion and Conclusion
- References
- Multiple Surface Segmentation Using Truncated Convex Priors
- 1 Introduction
- 2 Method
- 3 Experimental Methods
- 4 Results
- 5 Discussion and Conclusion
- References
- Statistical Power in Image Segmentation: Relating Sample Size to Reference Standard Quality
- 1 Introduction
- 2 Derivation of the Sample Size Formula
- 2.1 Sample Size for Segmentation Accuracy
- 2.2 Sample Size in Terms of the High Quality Reference Standard
- 3 Simulations
- 4 Results
- 5 Case Study
- 6 Discussion
- References
- Joint Learning of Image Regressor and Classifier for Deformable Segmentation of CT Pelvic Organs
- 1 Introduction
- 2 Method
- 2.1 Joint Learning of Image Regressor and Classifier
- 2.2 Deformable Segmentation with Regressor and Classifier
- 3 Experimental Results
- 4 Conclusion
- References
- Corpus Callosum Segmentation in MS Studies Using Normal Atlases and Optimal Hybridization of Extrinsic and Intrinsic Image Cues
- 1 Introduction
- 2 Methods
- 3 Evaluation Results
- 4 Conclusions
- References
- Brain Tissue Segmentation Based on Diffusion MRI Using l 0 Sparse-Group Representation Classification
- 1 Introduction
- 2 Approach
- 3 Experiments
- 3.1 Data
- 3.2 Diffusion Parameters
- 3.3 Comparison Methods
- 3.4 Results
- 4 Conclusion
- References
- A Latent Source Model for Patch-Based Image Segmentation
- 1 Introduction
- 2 Pointwise Segmentation and a Theoretical Guarantee
- 3 Multipoint Segmentation
- 4 Conclusions
- References
- Multi-organ Segmentation Using Shape Model Guided Local Phase Analysis
- 1 Introduction
- 2 Method
- 2.1 Quadrature Filters and Model Guided Local Phase Analysis
- 2.2 Integrating Region-Based and Edge-Based Energy in the Level-Set Method
- 2.3 Hierarchical Segmentation Pipeline and Multi-scale Phase Analysis
- 3 Experiments and Results
- 4 Discussion and Conclusion
- References
- Filling Large Discontinuities in 3D Vascular Networks Using Skeleton- and Intensity-Based Information
- 1 Introduction
- 2 Methodology
- 2.1 Method Overview
- 2.2 Gap Filling
- 2.3 Generating the Second-Order Tensor Field T
- 2.4 Deriving a Saliency Map S and Preferential Directions D from T
- 2.5 Generating the Enhancement Map E
- 3 Results
- 3.1 Synthetic Data
- 3.2 3D Images of Tumour Vasculature
- 4 Discussion
- References
- A Continuous Flow-Maximisation Approach to Connectivity-Driven Cortical Parcellation
- 1 Introduction
- 2 Methodology
- 2.1 Iterative Markov Random Field Formulation
- 2.2 Continuous Max-Flow Optimisation
- 3 Results
- 4 Discussion
- References
- A 3D Fractal-Based Approach towards Understanding Changes in the Infarcted Heart Microvasculature
- 1 Introduction
- 2 Methods
- 2.1 Data Acquisition and Pre-processing
- 2.2 Segmentation
- 2.3 Fractal-Based Methods
- 3 Results
- 4 Conclusions
- References
- Segmenting the Uterus in Monocular Laparoscopic Images without Manual Input
- 1 Introduction and Background
- 2 Methodology
- 3 Experimental Results
- 4 Conclusion
- References
- Progressive Label Fusion Framework for Multi-atlas Segmentation by Dictionary Evolution
- 1 Introduction
- 2 Proposed Method
- 2.1 Dictionary Construction
- 2.2 Multi-layer Label Fusion
- 3 Experiments
- 3.1 Dataset and Parameters
- 3.2 Hippocampus Segmentation Results
- 4 Conclusion
- References
- Multi-atlas Based Segmentation Editing with Interaction-Guided Constraints
- 1 Introduction
- 2 Multi-atlas Based Editing Method
- 2.1 Extraction of Local Interaction Combinations
- 2.2 Selection of Training Labels with respect to User Interactions
- 2.3 Label Fusion Based on User Interactions
- 3 Experimental Result
- 4 Conclusion
- References
- Quantitative Image Analysis II: Microscopy, Fluorescence and Histological Imagery
- Improving Convenience and Reliability of 5-ALA-Induced Fluorescent Imaging for Brain Tumor Surgery
- 1 Introduction
- 2 Concept of the Image Acquisition System
- 3 Imaging Formula
- 4 Experiment
- 4.1 Prototype System Building
- 4.2 Real Time Image Processing and Display
- 4.3 Quantitative Imaging Technique
- 5 Discussion and Conclusions
- References
- Analysis of High-throughput Microscopy Videos: Catching Up with Cell Dynamics
- 1 Introduction
- 2 Methods
- 2.1 Problem Formulation
- 2.2 Time Series Analysis
- 2.3 Dynamic Shape Model
- 2.4 MAP Segmentation and Association
- 3 Experimental Results
- 4 Summary and Conclusions
- References
- Neutrophils Identification by Deep Learning and Voronoi Diagram of Clusters
- 1 Introduction
- 2 Modeling Individual Cell Appearances by CNN
- 3 Modeling Cell Context by VDC
- 4 Experiments and Evaluation
- 5 Conclusions
- References
- U-Net: Convolutional Networks for Biomedical Image Segmentation
- 1 Introduction
- 2 Network Architecture
- 3 Training
- 3.1 Data Augmentation
- 4 Experiments
- 5 Conclusion
- References
- Co-restoring Multimodal Microscopy Images
- 1 Introduction
- 2 Data Acquisition
- 3 Methodology
- 3.1 Theoretical Foundation of Microscopy Image Restoration
- 3.2 Multimodal Microscopy Image Restoration Algorithm
- 3.3 Build a Look-Up Table for Better Initialization
- 3.4 Cell Segmentation and Classification Based on Co-restoration
- 4 Experimental Results
- 4.1 Qualitative Evaluation
- 4.2 Quantitative Evaluation
- 5 Conclusion
- References
- A 3D Primary Vessel Reconstruction Framework with Serial Microscopy Images
- 1 Introduction
- 2 Methods for 3D Vessel Reconstruction
- 2.1 Automated 2D Vessel Segmentation
- 2.2 Two-Stage Vessel Association with Vessel Cross-Sections
- 3 Experimental Results and Validation
- 4 Conclusion
- References
- Adaptive Co-occurrence Differential Texton Space for HEp-2 Cells Classification
- 1 Introduction
- 2 Method
- 2.1 Co-occurrence Differential Texton
- 2.2 HEp-2 Cell Image Representation in the Adaptive CoDT Feature Space
- 3 Experiments and Comparisons
- 3.1 Datasets
- 3.2 Experimental Results
- 4 Conclusion
- References
- Learning to Segment: Training Hierarchical Segmentation under a Topological Loss
- 1 Introduction
- 2 Method
- 3 Experiments and Results
- 4 Discussion and Conclusions
- References
- You Should Use Regression to Detect Cells
- 1 Introduction
- 2 Learning to Localize Cells
- 2.1 Defining the Proximity Score Map
- 2.2 Training and Evaluating a Regression Model
- 2.3 Detecting the Cells from the Proximity Score Map
- 3 Experimental Results
- 3.1 Datasets
- 3.2 Model Evaluation
- 4 Conclusion
- References
- A Hybrid Approach for Segmentation and Tracking of Myxococcus Xanthus Swarms
- 1 Introduction
- 2 Methodology
- 2.1 Context Builder
- 2.2 Cell Tracker
- 3 Experiments and Evaluations
- 4 Conclusions
- References
- Fast Background Removal in 3D Fluorescence Microscopy Images Using One-Class Learning
- 1 Introduction
- 2 Method
- 2.1 Estimating Background Noise
- 2.2 Detecting Undersized Windows
- 2.3 Recomputing Background Noise in "Undersized Windows"
- 3 Experiments and Results
- 4 Conclusions
- References
- Motion Representation of Ciliated Cell Images with Contour-Alignment for Automated CBF Estimation
- 1 Introduction
- 2 Ciliary Beating Frequency Estimation
- 2.1 Data Acquisition
- 2.2 Region Division
- 2.3 Cell Registration
- 2.4 Ciliary Beating Signal Extraction
- 2.5 Frequency Computation
- 3 Experimental Results
- 4 Conclusions
- References
- Multimodal Dictionary Learning and Joint Sparse Representation for HEp-2 Cell Classification
- 1 Introduction
- 2 Method
- 2.1 Supervised Dictionary Learning
- 3 Experiments and Results
- 3.1 Implementation Details
- 4 Conclusion
- References
- Cell Event Detection in Phase-Contrast Microscopy Sequences from Few Annotations
- 1 Introduction
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- Robust Muscle Cell Quantification
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- 4 Experiments
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- 5 Conclusion
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- Fast Cell Segmentation Using Scalable Sparse
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- 1 Introduction
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- Restoring the Invisible Details in Differential
- Interference Contrast Microscopy Images
- 1 Introduction
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- 1.2 Our Proposal and Algorithm Overview
- 2 Methodology
- 2.1 Gradient Images
- 2.2 Bandpass Filter
- 2.3 Motion Magnification
- 2.4 Combine Forward and Backward Motion Images
- 3 Experimental Results
- 3.1 Qualitative Evaluation
- 3.2 Quantitative Evaluation
- 4 Conclusion
- References
- A Novel Cell Detection Method Using Deep
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- 1 Introduction
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- 3 Experiments
- 4 Conclusion
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- Beyond Classification: Structured Regression
- for Robust Cell Detection Using Convolutional
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- 1 Introduction
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- 3 Experimental Results
- Data Set and Implementation Details.
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- Joint Kernel-Based Supervised Hashing for Scalable Histopathological Image Analysis
- 1 Introduction
- 2 Methodology
- Joint Kernel-Based Hashing:
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- Deep Voting: A Robust Approach
- Toward Nucleus Localization in Microscopy
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- 1 Introduction
- 2 Methodology
- 2.1 Learning The Deep Voting Model
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- Robust Cell Detection and Segmentation
- in Histopathological Images Using Sparse
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- 1 Introduction
- 2 Methodology
- 2.1 Detection via Sparse Reconstruction with Trivial Templates
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- Automatic in Vivo Cell Detection in MRI
- 1 Introduction
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- Automatic Vessel Segmentation
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- A Sparse Bayesian Learning Algorithm
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- Descriptive and Intuitive Population-Based
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- Liver Motion Estimation via Locally Adaptive
- Over-Segmentation Regularization
- 1 Introduction
- 2 Methodology
- Deformable Image Registration.
- Filtering of the Deformation Field.
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- 3 Evaluation and Results
- Results on 4DCT.
- Results on DCE-MRI.
- 4 Discussion and Conclusions
- Acknowledgments.
- References
- Motion-Corrected, Super-Resolution Reconstruction for High-Resolution 3D Cardiac Cine MRI
- 1 Introduction
- 2 Image Reconstruction
- 2.1 Motion-Compensated 3D Cine Reconstructions
- 2.2 Super-Resolution Reconstruction
- 3 MRI Experiments
- 4 Validation
- 5 Results
- 6 Discussion and Conclusion
- Acknowledgement.
- References
- Motion Estimation of Common Carotid Artery
- Wall Using a H8 Filter Based Block Matching
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- 1 Introduction
- 2 Methodology
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- Gated-tracking: Estimation of Respiratory
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- Solving Logistic Regression with Group
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- 1 Introduction
- 2 Solving Sparse Group Logistic Regression
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- 3 Characterizing TOF Based on Cine MRIs
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- Measure Accuracy:
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- 4 Conclusion
- Acknowledgement.
- References
- Spatiotemporal Parsing of Motor Kinematics
- for Assessing Stroke Recovery
- 1 Introduction
- 2 Approach
- 2.1 Creating Candidate Foreground Regions
- 2.2 Robust Exemplar Classification
- Max-projected Randomized Exemplar Classifiers:
- Dictionary of Paw Classifiers:
- Non-parametric Representation of Hand Posture:
- 2.3 Spatiotemporal Parsing
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- 3 Experimental Results
- Recording Setup:
- Grasping Diagnostics:
- 4 Conclusion
- References
- Longitudinal Analysis of Pre-term Neonatal
- Brain Ventricle in Ultrasound Images
- Based on Convex Optimization
- 1 Introduction
- Contributions:
- 2 Method
- Optimization Model:
- Sequential Convex and Dual Optimization:
- Dual Optimization Formulation.
- Proposition 1.
- 3 Experiments and Results
- Image Acquistion:
- Evaluation Metrics:
- Results:
- 4 Discussion and Conclusion
- Acknowledgments.
- References
- Multi-GPU Reconstruction of Dynamic
- Compressed Sensing MRI
- 1 Introduction
- 2 Method
- 2.1 Compressed Sensing Formulation for DCE-MRI
- Algorithm 1.
- 2.2 Multi-GPU Implementation
- 3 Result
- 3.1 Image Quality and Running Time Evaluation
- 3.2 Multi-GPU Performance Evaluation
- 4 Conclusion
- Acknowledgements.
- References
- Prospective Identification of CRT Super
- Responders Using a Motion Atlas and Random
- Projection Ensemble Learning
- 1 Introduction
- 2 Materials
- cine MR:
- T-MR:
- 3 Methods
- 3.1 Spatio-Temporal Motion Atlas
- Estimation of LV Geometry.
- Estimation of LV Motion.
- Spatial Normalisation.
- Motion Reorientation.
- vn
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- AHA Segmentation.
- vatlas
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- 4 Experiments and Results
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- 5 Discussion
- Acknowledgements.
- References
- Motion Compensated Abdominal Diffusion
- Weighted MRI by Simultaneous Image
- Registration and Model Estimation (SIR-ME)
- 1 Introduction
- 2 Methods
- 2.1 Simultaneous Image Registration and Model Estimation
- (SIR-ME) for Motion Compensated DW-MRI Parameter
- Estimation
- 2.2 Optimization Scheme
- Signal Decay Model (
- Estimation:
- Estimation of Transformation
- Reconstruction of High SNR DW-MRI Signal
- Estimation of Transformation
- 3 Results
- 4 Conclusions
- References
- Fast Reconstruction of Accelerated Dynamic
- MRI Using Manifold Kernel Regression
- 1 Introduction
- 2 Methods
- 2.1 Manifold Learning
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- 3 Experiments and Results
- 3.1 Manifold Creation
- 3.2 Comparison to State-of-the-Art Compressed Sensing
- Algorithms
- 4 Discussion
- References
- Predictive Modeling of Anatomy
- with Genetic and Clinical Data
- 1 Introduction
- 2 PredictionModel
- 2.1 Subject-Specific Longitudinal Change
- 0,
- 2.2 Learning
- 2.3 Prediction
- 3 Model Instantiation for Anatomical Predictions
- 3.1 Anatomical Phenotype
- 3.2 Health Similarities
- 4 Experiments
- 4.1 Volumetric Predictions
- 4.2 Anatomical Prediction
- 5 Conclusions
- Acknowledgements.
- References
- Joint Diagnosis and Conversion Time Prediction of Progressive Mild Cognitive Impairment (pMCI) Using Low-Rank Subspace Clustering and Matrix Completion
- 1 Introduction
- 2 Materials and Preprocessing
- 2.1 Materials
- 2.2 Preprocessing and Feature Extraction
- 3 Method
- 3.1 Notation
- X
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- 4 Results and Discussions
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- 5 Conclusion
- Acknowledgment.
- References
- Learning with Heterogeneous Data
- for Longitudinal Studies
- 1 Introduction
- 2 CO-MKL: Multiple Kernel Learning with Covariate
- 2.1 Background
- 2.2 Proposed Approach
- 3 Materials and Methods
- 4 Results
- -
- -
- -
- -
- -
- -
- 5 Conclusions
- References
- Parcellation of Infant Surface Atlas Using Developmental Trajectories of Multidimensional Cortical Attributes
- 1 Introduction
- 2 Method
- 2.1 Dataset and Cortical Surface Mapping
- 2.2 Atlas Parcellation Using Cortical Developmental Trajectories
- 3 Results
- 4 Conclusion
- References
- Graph-Based Motion-Driven Segmentation
- of the Carotid Atherosclerotique Plaque
- in 2D Ultrasound Sequences
- 1 Introduction
- 2 The Proposed Methodology
- 2.1 Group-Wise Image Registration
- 2.2 A Mutual-Information Map Reflecting Kinematic Dependencies
- 2.3 Graph-Based Segmentation of the Mutual-Information Map
- g)
- f
- g,f
- 3 Evaluation Process and Results
- 4 Discussion
- References
- Cortical Surface-Based Construction of Individual Structural Network with Application to Early Brain Development Study
- 1 Introduction
- Violation of Cortical Topological Properties.
- Sensitivity to Intensity Heterogeneity.
- Influence by Patch Size Heterogeneity.
- 2 Methods
- Subjects and Image Acquisition.
- Image Preprocessing.
- Cortical Surface Reconstruction and Registration.
- Construction of Individual Networks.
- Network Metrics.
- 3 Results
- 4 Conclusion
- References
- NEOCIVET: Extraction of Cortical Surface and Analysis of Neonatal Gyrification Using a Modified CIVET Pipeline
- 1 Introduction
- 2 Methods
- A)
- B)
- C)
- D)
- E)
- F)
- G)
- H)
- I)
- J)
- K)
- L)
- 2.1 Subjects and MRI Acquisition
- 2.2 Classification of Brain Tissues
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- 2.3 Surface Fitting
- 2.4 Surface-Based Morphological Measurements
- 2.5 Construction of Age-Specific Surface Templates and Registration
- 2.6 Other Technical Considerations and Parameter Selection
- 3 Application and Clinical Utility of NEOCIVET
- 3.1 Statistical Analyses
- 3.2 Results
- 4 Discussion and Conclusion
- References
- Learning-Based Shape Model Matching:
- Training Accurate Models with Minimal Manual
- Input
- 1 Introduction
- 2 Methods
- 2.1 Groupwise Non-rigid Registration
- 2.2 RF Regression-Voting in the CLM Framework
- 3 Experiments and Evaluation
- Datasets:
- 3.1 Guided Groupwise Non-rigid Registration and Refinement
- 3.2 Estimation of GNR Accuracy in the Absence of Ground Truth
- 3.3 Performance of GNR-trained RFRV-CLM on New Images
- 4 Discussion and Conclusions
- Acknowledgments.
- References
- Scale and Curvature Invariant Ridge Detector
- for Tortuous and Fragmented Structures
- 1 Introduction
- 2 Methods
- Curved-Support Gaussian Models.
- Unsupervised SCIRD.
- Supervised SCIRD.
- 3 Experiments and Results
- Datasets.
- IVCM
- BF2D
- VC6
- Parameters Setting.
- Results and Discussion.
- 4 Conclusion
- References
- Boosting Hand-Crafted Features
- for Curvilinear Structure Segmentation
- by Learning Context Filters
- 1 Introduction
- 2 Proposed Approach
- Unsupervised Filter Learning.
- D
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- L
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- 3 Experiments
- Datasets.
- IVCM
- BF2D
- VC6
- Experimental Setup.
- Results and Discussion.
- 4 Conclusion
- References
- Kernel-Based Analysis of Functional Brain
- Connectivity on Grassmann Manifold
- 1 Introduction
- 2 Functional Connectivity Classification on Manifold
- 2.1 Grassmann Manifold
- 2.2 Identification of Discriminative Functional Connections
- 3 Material
- Algorithm 1.
- 4 Results and Discussion
- Grass-Kernel)
- GK-LogE)
- GK)
- LK)
- 5 Conclusion
- References
- A Steering Engine: Learning 3-D Anatomy Orientation Using Regression Forests
- 1 Introduction
- 2 Methods
- 2.1 Problem Definition
- 2.2 Regression-Based Anatomy Colatitude Prediction
- 2.3 Iterative Colatitude Prediction and Patch Reorientation
- 2.4 Rotation-Invariant Integral Image for Fast Feature Calculation
- 3 Experimental Results
- Local Anatomy Orientation Detection:
- Vertebrae
- Aorta
- Anatomical Structure Tracing:
- 4 Conclusions
- References
- Automated Localization of Fetal Organs in MRI
- Using Random Forests with Steerable Features
- 1 Introduction
- 2 Method
- 3 Experiments
- 4 Conclusion
- References
- A Statistical Model for Smooth Shapes in Kendall Shape Space
- 1 Introduction and Related Work
- 2 Methods
- 2.1 Statistical Shape Model Using Riemannian Distances and Smoothness Priors
- 2.2 Efficient Model of Likelihood of Image Data Given Object Shape
- 2.3 Parameter Inference Using ExpectationMaximization
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- 3 Results
- Validation on Simulated Data:
- Evaluation on Clinical Data:
- Conclusions.
- References
- A Cross Saliency Approach to
- Asymmetry-Based Tumor Detection
- 1 Introduction
- 2 Cross Saliency
- 2.1 Cross Patch Distinctness
- 2.2 Patch Flow
- 2.3 Combining the Measures
- 3 Experiments
- 3.1 Unsupervised Tumor Detection on BRATS2014
- 3.2 Tumor Detection in Breast Mammogram
- 3.3 Stability under Variation in Mid-Sagittal Plane Estimation
- 4 Conclusion
- References
- Grey Matter Sublayer Thickness Estimation
- in the Mouse Cerebellum
- 1 Introduction
- 2 Methods
- 2.1 Cerebellum Extraction and Tissue Segmentation
- 2.2 Fissure Extraction
- 2.3 Grey Matter Thickness Estimation
- 2.4 Purkinje Layer Extraction and Sublayer Thickness Estimation
- 2.5 Grey Matter Function Aware Region Parcellation
- 3 Experimental Data and Validation
- 4 Conclusion and Discussion
- References
- Unregistered Multiview Mammogram Analysis
- with Pre-trained Deep Learning Models
- 1 Introduction
- Literature Review:
- Contributions:
- 2 Methodology
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- 3 Materials and Methods
- 4 Results
- 5 Discussion and Conclusion
- References
- Automatic Craniomaxillofacial Landmark
- Digitization via Segmentation-Guided
- Partially-Joint Regression Forest Model
- 1 Introduction
- 2 Automatic CMF Landmark Digitization
- 2.1 Traditional Regression Forest Model for Landmark Digitization
- 2.2 Segmentation-Guided Partially-Joint Regression Forest
- (S-PRF) Model
- Partially-Joint Regression Forest Model:
- Segmentation-Guided Strategy:
- d
- 3 Experiments, Results and Discussion
- 3.1 Data Description and Parameter Setup
- 3.2 Experimental Results
- Effect on the Segmentation-Guided Strategy:
- Effect on the Use of Partially-Joint Versus Fully-Joint Models:
- Effect on Adding Additional MSCT Images into the Training Dataset:
- Effect on Features:
- Comparison with Registration-Based Landmark Detection:
- Effect on the Use of Scaling Coefficient:
- 4 Conclusion
- References
- Automatic Feature Learning for Glaucoma
- Detection Based on Deep Learning
- 1 Introduction
- 2 Method
- 2.1 Feature Learning Based on Deep Convolutional Neural Network
- Convolutional Layers.
- L
- L
- L
- L
- L
- L
- L
- w
- 1
- w
- Multilayer Perceptron Convolution Layers.
- Contextualizing Training Strategy.
- 2.2 Glaucoma Classification
- Disc Segmentation.
- Dropout and Data Augmentation.
- Automatic Classification by Softmax Regression.
- 3 Experiments
- 3.1 Evaluation Criteria
- 3.2 Experimental Setup
- 3.3 Comparison of Different Types of CNN Architectures
- -
- -
- -
- -
- -
- 3.4 Glaucoma Diagnosis
- 4 Conclusion
- References
- Fast Automatic Vertebrae Detection and
- Localization in Pathological CT Scans - A Deep
- Learning Approach
- 1 Introduction
- 2 Methods
- 2.1 Point Selection
- 2.2 Feature Extraction
- 2.3 Deep Neural Network
- 2.4 Centroid Estimation
- 2.5 Refinement
- 3 Experiments and Results
- 4 Discussion
- Acknowledgement.
- References
- Guided Random Forests for Identification of Key Fetal Anatomy and Image Categorization in Ultrasound Scans
- 1 Introduction
- 2 Guided Random Forests
- 2.1 Localizing Object of Interests
- 2.2 Feature Sets for e the Learning Algorithm
- 2.3 Training and Testing
- 3 Experiments
- 3.1 Dataset
- 3.2 Evaluation Protocol and Metrics
- 4 Results
- 5 Discussion and Future Work
- References
- Dempster-Shafer Theory Based Feature
- Selection with Sparse Constraint for Outcome
- Prediction in Cancer Therapy
- 1 Introduction
- 2 Backgrounds on Dempster-Shafer Theory
- 3 Method
- R
- 4 Experimental Results
- 5 Conclusion
- Acknowledgements.
- References
- Disjunctive Normal Shape and Appearance
- Priors with Applications to Image Segmentation
- 1 Introduction
- 2 Disjunctive Normal Shape Model
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- 5 Segmentation Algorithm
- 6 Experiments
- Prostate Central Gland Segmentation:
- Full Prostate Segmentation:
- 7 Conclusion
- Acknowledgments.
- References
- Positive Delta Detection for Alpha Shape Segmentation of 3D Ultrasound Images of Pathologic Kidneys
- 1 Introduction
- 2 Methods
- 2.1 Local Phase-Based 3D Positive Delta Detection
- 2.2 Patient Specific Pos sitional Maps via Alpha Shapes
- 2.3 Active Contours Formulation
- 2.4 Complete Segmentation Framework of Renal Structures in 3DUS
- 3 Results and Discussion
- 4 Conclusions
- References
- Non-local Atlas-guided Multi-channel Forest
- Learning for Human Brain Labeling
- 1 Introduction
- 2 Method
- Notations.
- A
- A.
- 2.1 Atlas-guided Multi-channel Forest Learning
- A,
- Sampling Strategy:
- Feature Extraction:
- 1 channel
- channels
- 2.2 Single-ROI and Multi-ROI Labeling
- Single-ROI Labeling:
- 1)
- 2)
- 3)
- Multi-ROI Labeling:
- 2.3 Haar-Based Multi-Class Contexture Model (HMCCM)
- Training:
- Testing:
- 3 Experimental Results
- Parameters:
- LONI-LPBA40 Dataset:
- IXI Dataset:
- 4 Conclusion
- References
- Model Criticism
- for Regression on the Grassmannian
- 1 Introduction
- Contributions.
- 2 Model Criticism for Regression in Euclidean Space
- Review of Kernel-Based Two-Sample Testing [3].
- Model Criticism Using Two-Sample Testing.
- 3 Model Criticism for Regression on the Grassmannian
- Drawing Random Samples on the Grassmannian.
- Yobs
- Y
- Yobs
- Y
- Y
- Y
- Zi
- Y
- Y
- Is
- Y
- Y
- Zi
- Is
- Yest
- Yest
- Y
- Y
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- Y
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- Kernels for Model Criticism on the Grassmannian.
- X,Y)
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- Y
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- Y
- Model Criticism on the Grassmannian.
- Y
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- Ya
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- 4 Experimental Results
- Synthetic Data.
- (1) Different Data Distributions.
- (2) Different Regression Models.
- Real Data.
- (1) Corpus Callosum Shapes.
- (2) Rat Calvarium Landmarks.
- 5 Discussion
- Acknowledgments.
- References
- Sample Size Estimation for Outlier Detection
- 1 Introduction
- 2 Methods
- 2.1 A Confidence Interval for
- 2.2 Estimating Sample Sizes
- 3 Experiments
- 3.1 Plausibility Test: Our Formula vs. Monte Carlo Estimate
- 3.2 Sample Size Estimation for Given
- 3.3 Application to Real Data
- 4 Conclusion
- Acknowledgement.
- References
- Multi-scale Heat Kernel Based Volumetric
- Morphology Signature
- 1 Introduction
- 2 Methods
- 2.1 Theoretical Background
- 2.2 Discrete Multi-scale Volumetric Morphology Signature
- Ti
- T)(Ti
- T)
- Ti
- T
- Ti
- Ti
- T
- 2.3 Internal Structure Feature Selection
- 3 Experimental Results
- 3.1 Synthetic Data Results
- 3.2 Application to Alzheimer's Disease
- 3.3 Comparison with Freesurfer Thickness Feature
- 4 Conclusions and Future Work
- References
- Structural Brain Mapping
- 1 Introduction
- Brain Net.
- Approach.
- 2 Theoretic Background
- Graph Embedding.
- Harmonic Map.
- g)
- g
- 3 Computational Algorithms
- Step 1: Isomorphic Graph Embedding.
- Step 2: ConstrainedHarmonicMapping.
- Algorithm 1.
- Input:
- 4 Experiments
- Brain Net Extraction.
- Structural Brain Mapping.
- 5 Discussion
- 6 Conclusion
- Acknowledgments.
- References
- Author Index
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