
Technical Assessment of the Man-in-Simulant Test Program
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Content
- Technical Assessment of the Man-In-Simulant Test (MIST) Program
- Copyright
- Preface
- Contents
- Acronyms
- Executive Summary
- GENERAL CONCLUSIONS AND RECOMMENDATIONS
- 1 Introduction
- BACKGROUND
- CHARGE TO THE COMMITTEE
- STUDY APPROACH
- 2 Test Protocol
- UNDERLYING CONCEPTS
- Introduction
- Materials Evaluation
- Suit Technology
- Evaluation of Suit Systems
- METHODOLOGY
- Methods for Evaluating Protective Clothing
- MIST Test Procedure
- Body Region Hazard Analysis
- Evaluation of Suits against Exposure to HD (Local Analysis)
- Evaluation of Suits against Exposure to VX (Systemic Analysis)
- 3 Simulant Section
- IMPORTANCE OF DERMAL PENETRATION
- USE OF SIMULANT TO PREDICT DERMAL PENETRATION
- SELECTION OF A SIMULANT
- TOXICITY OF METHYL SALICYLATE
- FINAL CHOICE OF A SIMULANT FOR MIST
- 4 Test Methods and Sampler Selection
- PURPOSES OF MONITORING
- RATIONALE FOR THE SELECTION OF MONITORING METHODS
- CHAMBER MONITORING
- OPTIONS FOR IN-SUIT MONITORING
- Active Sampling Systems
- Overview
- External Pumps and Tubes
- Pumps and Sampling Systems inside the Protective Garment
- Passive Samplers
- Natick Sampler
- 5 Assumptions and Limitations
- TEST PROTOCOL CONSIDERATIONS
- HUMAN FACTORS CONSIDERATIONS
- ACETYLCHOLINESTERASE INHIBITION AS A BIOLOGICAL MARKER
- BIOLOGICAL INTERPRETATION OF THE MIST/BRHA
- 6 Conclusions and Recommendations
- SPECIFIC CONCLUSIONS AND RECOMMENDATIONS
- GENERAL CONCLUSIONS AND RECOMMENDATIONS
- References
- APPENDICES
- Appendix A Body Region Hazard Analysis
- INTRODUCTION
- CONCEPTS
- OPPORTUNITIES AND APPLICATIONS
- NOMENCLATURE
- REFERENCES
- Appendix B Panel and Committee Meetings
- PANEL MEETINGS
- Presenters
- Presenters
- FULL COMMITTEE MEETINGS
- Presenters
- Presenters
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