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Immunity to Immunotherapy in Cancer: Mechanisms and Limitations explores the intricate interplay between cancer therapy and the immune system, addressing why some patients do not respond to immunotherapy and scientific solutions in development. The book examines molecular strategies of immune evasion within the tumor microenvironment, providing insights into factors like tumor heterogeneity and immune checkpoint mechanisms that contribute to resistance. Highlighting promising approaches such as combination therapies, personalized medicine, and novel immunotherapeutic agents, the book aims to enhance patient outcomes and advance cancer immunotherapy.Designed as a comprehensive guide for professionals and researchers, this textbook offers an overview of the latest scientific discoveries and practical applications in cancer therapy. It serves as an invaluable resource for scientists, doctors, academicians, and students, presenting a path toward more effective, non-toxic, and customized cancer treatments. This book is essential for anyone interested in the future of cancer therapy.
- Provides an in-depth examination of the molecular strategies of immune evasion and the tumor microenvironment, offering critical insights into why some patients do not respond to immunotherapy
- Bridges the gap between current research and practical therapeutic applications in cancer immunotherapy
- Highlights the latest advancements in cancer therapy, discussing cutting-edge strategies such as combination therapies, personalized medicine, and novel immunotherapeutic agents
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978-0-443-41552-4 (9780443415524)
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Part A: Cancer Immunity1. Introduction to Immunity in Cancer2. Role of Innate Immunity in Cancer Immunology3. Role of Dendritic Cells in Cancer Immunology4. Role of Natural Killer Cells in Cancer Immunology5. Role of B-Cells in Tumor Immunity6. Role of CD4+ T-Cells in Cancer Immunology7. Role of Regulatory T-Cells and Th17 Cells in Tumor Microenvironment8. Role of Monocytes, Macrophages, and Polymorphonuclear Cells in Cancer Immunology9. Role of Cytokines in Cancer Immunology10. Role of Chemokines and Chemokine Receptors in Cancer Immunology11. Role of the Inflammasome in Cancer Immunology12. Current Advanced Immunological Tools and Databases in Tumor Immunity13. Tumor Heterogeneity and Therapeutic ResistancePart B: Cancer Immunotherapy14. Cancer Immunotherapy: Pros, Cons, and Beyond15. Role of Monoclonal Antibody, Immune Checkpoint Inhibitors, and Programmed Death Ligand 1 in Cancer Immunotherapy16. Role of Chimeric Antigen Receptor-T Cell in Cancer Immunotherapy17. Role of Small Molecule-Based Drugs in Cancer Immunotherapy18. Role of Adoptive Cell Therapy in Cancer Immunotherapy19. Role of Cancer Vaccines in Cancer Immunotherapy20. Role of Radiotherapy/Chemotherapy in Cancer Immunotherapy