Asymmetric Synthesis V2

ContributorsPreface1. Asymmetric Hydroboration I. Introduction II. Diisopinocampheylborane III. Dilongifolylborane IV. Limonylborane V. Monoisopinocampheylborane VI. Conclusion References2. Reductions with Chiral Boron Reagents I. Introduction II. Chirally Modified Boranes III. Chirally Modified Borohydrides References3. Reductions with Chiral Modifications of Lithium Aluminum Hydride I. Introduction II. Alcohol-Modified Lithium Aluminum Hydride III. Amine-Modified Lithium Aluminum Hydride IV. Amino Alcohol-Modified Lithium Aluminum Hydride V. Aminodiol-Modified Lithium Aluminum Hydride VI. Conclusions References4. Reductions with Chiral Dihydropyridine Reagents I. Introduction II. Summary of the Mechanistic Studies of NADH Model Reactions III. Asymmetric Reductions with Chiral NADH Model Compounds IV. Factors Affecting Product Stereochemistry in Asymmetric Reductions with Chiral NADH Model Compounds V. Approach to Chiral NADH Models of Higher Stereoselectivity VI. Simulation of Enzyme Active Site Composed of Peptide Chain VII. Concluding Remarks References5. Application of Cram's Rule: Addition of Achiral Nucleophiles to Chiral Substrates I. Introduction II. Variation of Reaction Conditions III. Application of Cram's Rule to Asymmetric Synthesis IV. Remote Stereochemical Control References6. Addition of Chiral Nucleophiles to Aldehydes and Ketones I. Introduction II. Organometallic Reagents Used in a Chiral Environment III. Addition of Carbanions a to a Chiral Sulfoxide Group IV. Chiral Ester Enolates References7. Noncatalytic Additions to a,ß-Unsaturated Carbonyl Compounds I. Introduction II. Conjugate Additions of Chiral a,ß-Unsaturated Carbonyl Derivatives III. Conjugate Additions with Chiral Nucleophiles References8. Addition of Organometallic Reagents to Chiral Vinylic Sulfoxides I. Introduction II. 1-Alkenyl Sulfoxides III. 2-Alkenyl Sulfoxides IV. 2-Cycloalkenone Sulfoxides V. Conclusion References9. Alkylation of Imine and Enamine Salts I. Introduction II. Formation of Azaallyl Metal Reagents and Enamines III. Structure of Azaallyl Metal Reagents IV. Electrophilic Substitution of Azaallyl Metal Regents and Enamines V. Asymmetric Syntheses Employing Chiral Azaallyl Metal Reagents VI. Asymmetric Syntheses Employing Chiral Enamines ReferencesIndex