Biophysical Aspects of Cardiac Muscle

List of ContributorsForewordPrefaceI. The A. F. Huxley Symposium Lecture On Arguing from One Kind of Muscle to AnotherII. Gating Processes in Excitable Membranes Intramembranous Charge Movement and Control of Cellular Functions by Membrane Voltage Electrical Properties of Amphibian Slow Muscle Fibers Charge Movement in the Membrane of Striated Muscle Local Anesthetic Action on Inactivation of the Na Channel in Nerve and Skeletal Muscle: Possible Mechanisms for Antiarrhythmic Agents Models of Gating Current and Sodium Conductance InactivationIII. Ionic Transport Mechanisms in Generation of Cardiac Action Potential Plateau Inward Rectifier: Carriers Vs. Channels Calcium Transport in Excitable Membranes Voltage Dependence of Tetrodotoxin Action in Mammalian Cardiac Muscle The Effect of Cesium Ions on 42K Efflux in Cardiac Purkinje Fibers Potassium Currents in Ventricular Muscle General Discussion on "The Inward Rectifier"IV. Structure and Function of the Sarcotubular System Introductory Remarks: Structural Basis of E-C Coupling Three-Dimensional Structure of Muscle Fiber Optical Indications of Excitation-Contraction Coupling in Striated Muscle Fluorescence Signals from Skeletal Muscle Fibers The Aequorin Signal During Activation of MuscleV. E-C Coupling in Heart Muscle The Effect of Extracellular Potassium on the Excitation Contraction Coupling in Frog Heart A Ca-Transport System for Activation of Tension in Frog Ventricular Muscle E-C Coupling Studies on Skinned Cardiac Fibers Membrane Control of Cardiac Contractile SystemsVI. Mechanisms of Drug Action in Cardiac Muscle Digitalis: Inotropic and Arrhythmogenic Effects on Membrane Currents in Cardiac Purkinje Fibers Two Mechanisms for the Inotropic Action of Ouabain on Sheep Cardiac Purkinje Fiber Contractility Glycoside Induced Stimulation of Membrane Na-K ATPase-Fact or Artifact? Analysis of Catecholamine Action in Frog Atrial Fibers