Scientific and Engineering Principles
Proceedings of the Sixth International Fermentation Symposium Held in London, Canada, July 20-25, 1980
Published on 22. October 2013
808 pages
978-1-4831-4845-8 (ISBN)
Description
Advances in Biotechnology, Volume I: Scientific and Engineering Principles is the first of a series of three volumes and is based on the proceedings of the Sixth International Fermentation Symposium (IFS-6) held in London, Ontario, Canada, 20-25 July 1980. This volume is organized into 13 sections and contains 111 papers which represent about 80% of the total submitted. Section I contains papers on microbial cultures. Section II presents studies on recombinant DNA and microbial genetics. The papers in Section III deal with plant and animal cell and tissue culture. Section IV examines the microbial oxidation of hydrocarbons. Sections V and VI focus on continuous cultures and free-cell fermentation, respectively. Section VII examines process dynamics and control. Section VIII takes up computer applications in biotechnology, while Section IX covers process instrumentation and analytical methods. Section X contains papers on transport phenomena, mixing and scale-up. Section XI examines the design and operation of unconventional bioreactors. Sections XII covers fixed-, fluidized- and semi-fluidized bed bioreactors, while Section XIII presents studies on immobilization bioreactors. The volume also includes invited keynote addresses of Nobel Laureate, Professor Joshua Lederberg, and Professor Elmer L. Gaden, Jr. Abstracts of the round-table discussion on Technology Transfer and Economics, and on Biotechnology Training Programs are presented as appendices.
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PrefaceGuest Editorial I. Biochemical Engineering: Where Has it Been and Where is it Going?Guest Editorial II. Genetics and Industrial Microbiology: Still Further HorizonsSection I. Microbial Cultures: Screening, Improvement, Patents 1. Strain Improvement Programs in Antibiotic-Producing Microorganisms - Present and Future Strategies 2. New Organisms of Economic Importance: the Case of Frankia 3. Mixed Cultures in Industrial Processes 4. Cultures and Patents 5. Production of Pharmacologically Active Agents from Microbial Origin 6. Screening of Basidiomycetes for the Production of New Antibiotics 7. Screening of Bacterial Isolates for Antigonococcal Activities 8. Isolation of Carboxyl Proteinases of Microbial Origin on Pepstatinsepharose Resin 9. Rapid Strain Selection for Citric Acid Production 10. Use of Cerulenin in Selecting Improved Mutants of Daunorubicin-Producing Streptomycete 11. Improvement of the Daunorubicin Fermentation Realized at 10,000 Liter Fermentor Scale 12. Studies on the Avermectin Fermentation 13. The Influence of Oxygen Concentration on Microbial Insecticide ProductionSection II. Recombinant DNA and Microbial Genetics 14. Enzymatic Hydrolysis of some Penicillins and Cephalosporins by Cloned Escherichia coli Acylase 15. Expansion of the Host Range of Pl and Mu Phages and Gene Transfer between Intergeneric Bacteria 16. Stability of trp Operon Recombinant Plasmid in E. coli 17. Genetic Control of Dikaryotic Fruiting in the BasidiomyceteSection III. Cell and Tissue Culture - Plant and Animal 18. Advances in Plant Cell Culture towards Improved Yields of Secondary Products (Alkaloids) 19. Aspects on Scale-up and Mass Cultivation of Plant Tissue Culture 20. Present and Future Trends in Plant Tissue Culture 21. Effects of Media Constituents on the Formation of Secondary Products in Cell Suspension Cultures of Catharanthus roseus 22. Hormonal Regulation of Scopoletin and Scopolin Productions in Tobacco Tissue Culture 23. Engineering Characterization of Animal Cell and Virus Production Using Controlled Charge MicrocarriersSection IV. Microbial Oxidation of Hydrocarbons 24. Uptake and Oxidation of Hydrocarbons by a Mutant Derived from Itaconate-Producing Yeast 25. Study of Hydroxylase and its Components in Candida tropioalis Grown on Alkane 26. Plasmid Involvement in Bacterial Degradation of Phenanthrene 27. Induction of Enzymes for n-Alkane Degradation in Two Strains of Pseudomonas aeruginosa 28. Structural Changes of the TOL Plasmid pWWO 29. Utilization of n-Alkanes by Microorganisms: Biological Aspects of TransportSection V. Continuous Cultures 30. The Utility of Chemostat Cultures in Studies of Microbial Physiology 31. Continuous Culture: Some Contemporary Problems from Another Viewpoint 32. Nutrient Control of Growth at the Cellular Level: Some Studies Conducted with Candida utilis in Continuous Phased Culture 33. Continuous Culture: Its Influence on Engineering Practice 34. The Enzyme Activity as Growth Rate Limiting Step in a Chemostat 35. Selection of Escherichia coli with Increased Endoenzyme Synthesis in Continuous Culture 36. Continuous Process for Production of Citric Acid 37. Kinetics of Virus Replication and Glucoamylase Biosynthesis in Aspergillus niger Repeated Fed-Batch Culture 38. Auto-Selection of Very Rapidly Growing Microorganisms 39. Gel-Forming Exopolysaccharide Production by Alcaligenes faecalis Grown in Nitrogen-Limited Continuous Culture 40. New Developments in the Elucidation of the Mechanisms of the Pasteur and Crabtree Effects in Bacteria 41. The Crabtree Effect in Saccharomyces cerevisiae: Primary Control Mechanism or Transient? 42. Regulatory Aspects in Yeast Metabolism 43. Growth of Hansenula polymorpha on Mixed Substrates and Regulation of Alcohol Oxidase Synthesis 44.
