Integration and Visualization of Gene Selection and Gene Regulatory Networks for Cancer Genome
Published on 9. May 2018
200 pages
978-0-12-816357-3 (ISBN)
Description
Integration and Visualization of Gene Selection and Gene Regulatory Networks for Cancer Genome helps readers identify and select the specific genes causing oncogenes. The book also addresses the validation of the selected genes using various classification techniques and performance metrics, making it a valuable source for cancer researchers, bioinformaticians, and researchers from diverse fields interested in applying systems biology approaches to their studies.
- Provides well described techniques for the purpose of gene selection/feature selection for the generation of gene subsets
- Presents and analyzes three different types of gene selection algorithms: Support Vector Machine-Bayesian T-Test-Recursive Feature Elimination (SVM-BT-RFE), Canonical Correlation Analysis-Trace Ratio (CCA-TR), and Signal-To-Noise Ratio-Trace Ratio (SNRTR)
- Consolidates fundamental knowledge on gene datasets and current techniques on gene regulatory networks into a single resource
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Shruti Mishra | Debahuti Mishra | Sandeep Kumar Satapathy
Integration and Visualization of Gene Selection and Gene Regulatory Networks for Cancer Genome
Book
05/2018
Academic Press
€93.00
Shipment within 15-20 days
Persons
Dr. Mishra is currently working as an Associate Professor in the Department of Computer Science & Engineering, Vignana Bharathi Institute of Technology, Hyderabad and as former Head of the Department for the same institution. She was earlier working as an Assistant Professor, Department of Computer Science & Engineering, Institute of Technical Education & Research, Siksha O Anusandhan (Deemed-to-be University), Bhubaneswar, Odisha, India. She has guided 5 M.Tech thesis and more than 30 B.Tech students. Dr. Mishra has around 22 publications in various peer-reviewed journals and conference, 3 book chapters and 1 book to her credit. Her area of research is basically in Data Mining, Bioinformatics and Machine Learning. She is currently into the field of Geoinformatics and Deep Learning.Dr. Sandeep Kumar Satapathy is currently working as an Associate Professor in the Department of Computer Science & Engineering and is also the Head of the Department of Information Technology at Vignana Bharathi Institute of Technology. Dr. Satapathy did his doctorate in the field of Data Mining & Machine Learning, and his thesis included a detailed classification of brain EEG signals using machine learning techniques. He has been member to various academic committees within the institution. Also, he has been an active reviewer in various peer reviewed journals and presented papers in prestigious conferences. He has also reviewed many research articles and books for Elsevier for possible publication. Prof. Satapathy is highly engrossed into the area of deep learning and image processing. He has many research publications to his credit, that is more than 25 research articles, book chapters and has guided more than 10 master thesis. Dr. Satapathy has also authored a book entitled Frequent Pattern Discovery from Gene Expression Data: An Experimental Approach. He is currently member of many professional organizations and societies. His research interest includes Bioinformatics and computational approaches to biomedical field.
Content
1. Literature Review2. SVM-BT-RFE: An Improved Gene Selection Framework Using Bayesian T-Test Embedded in Support Vector Machine (Recursive Feature Elimination) Algorithm3. Enhanced Gene Ranking Approaches Using Modified Trace Ratio Algorithm for Gene Expression Data4. SNR-TR Gene Ranking Method: A Signal-to-Noise Ratio Based Gene Selection Algorithm Using Trace Ratio for Gene Expression Data5. Visualization of Interactive Gene Regulatory Network Using Gene Selection Techniques from Expression Data6. Conclusion and Future Work
