Functional Imaging and Modeling of the Heart
6th International Conference, FIMH 2011, New York City, NY, USA, May 25-27, 2011, Proceedings
Published on 20. May 2011
XIII, 439 pages
978-3-642-21028-0 (ISBN)
Description
This book constitutes the proceedings of the 6th International Conference on Functional Imaging and Modeling of the Heart, held in New York City, NY, USA in May 2011.
The 24 revised full papers presented together with 29 revised poster papers were carefully reviewed and selected from about 120 initial submissions. The contributions feature current research and development efforts in the fields of cardiovascular modeling, physiology, and image-based analysis, at a range of scales and imaging methods. Topics addresses are such as imaging, signal and image processing, applied mathematics, biomedical engineering and computer science; biologically oriented fields such as cardiac physiology and biology; as well as clinical issues such as cardiology, radiology and surgery, with a common interest in the heart.
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Dimitris N. Metaxas | Leon Axel
Functional Imaging and Modeling of the Heart
6th International Conference, FIMH 2011, New York City, NY, USA, May 25-27, 2011, Proceedings
Book
05/2011
1st Edition
Springer
€53.49
Shipment within 5-7 days
Content
- Title
- Preface
- Organization
- Table of Contents
- Oral Session 1: Cardiac Electrophysiology
- Anode Make and Break Excitation Mechanisms and Strength-Interval Curves: Bidomain Simulations in 3D Rotational Anisotropy
- Introduction
- Methods
- Results
- Discussion
- References
- Comparing Simulated Electrocardiograms of Different Stages of Acute Cardiac Ischemia
- Motivation
- Methods and Materials
- Modeling Ischemic Myocytes
- Modeling Heterogeneous Excitation Propagation
- Calculation of Body Surface Electrocardiograms
- Results
- Cell Simulations
- Tissue Simulations
- Discussion and Conclusions
- References
- Interpreting Optical Mapping Recordings in the Ischemic Heart: A Combined Experimental and Computational Investigation
- Introduction
- Methods
- Optical Mapping Experiments
- Modeling Ischemia-Induced Alterations in Electrophysiology
- Optical Mapping Model
- Data Analysis
- Results
- Optical Mapping Experiments
- Border Zone Effects on Epicardial Transmembrane Potential
- Optical Signal and Transmembrane Potential Comparison
- Varying Optical Mapping Penetration Depth
- Conclusions
- References
- Towards High Resolution Computational Models of the Cardiac Conduction System: A Pipeline for Characterization of Purkinje-Ventricular-Junctions
- Introduction
- Material and Methods
- Tissue Preparation
- Image Acquisition
- Geometric Reconstruction and Structural Analysis
- Results
- Discussion and Conclusions
- References
- Poster Session 1: Cardiac Electrophysiology
- Dynamic Classification of Cellular Transmural TransMembrane Potential (TMP) Activity of the Heart
- Introduction
- Methods
- Co-clustering within a Cardiac Electrophysiology Context
- Bipartite Spectral Graph Co-clustering Algorithm
- Experimental Results
- Simulated Data Sets
- Results
- Quantitative Analysis
- Discussion and Conclusion
- References
- Cardiac Deformation from Electro-Anatomical Mapping Data: Application to Scar Characterization
- Introduction
- Cardiac Deformation Estimation
- Data Pre-processing
- Deformation Estimation
- Statistical Analysis
- Clinical Data
- Results
- Discussion
- Conclusions
- References
- Comparing Image-Based Respiratory Motion Correction Methods for Anatomical Roadmap Guided Cardiac Electrophysiology Procedures
- Introduction
- Method
- Diaphragm or Heart Border Tracking
- Tracheal Bifurcation Detection
- CS Catheter Detection
- Results
- Diaphragm and Heart Border Tracking Errors
- Tracheal Bifurcation Detection Errors
- Validation Using the Lasso Catheter
- Conclusion and Discussions
- References
- Automatic Segmentation of Left Atrial Scar from Delayed-Enhancement Magnetic Resonance Imaging
- Introduction
- Methods
- Patient Protocol
- Left Atrium Segmentation and Image Registration
- Segmentation of Atrial Lesions
- Evaluation of Novel Approach
- Results
- Discussion and Conclusion
- References
- Estimation of Activation Times in Cardiac Tissue Using Graph Based Methods
- Introduction
- Methods
- The Bidomain Model
- The Graph Based Model
- Results
- Method Comparison for Different Mesh Resolutions
- Method Comparison in a Slab of Heterogeneous, Anisotropic Tissue
- Method Comparison in a Rabbit Ventricular Mesh
- Conclusions
- References
- Automatic Segmentation of Cardiac CTs - Personalized Atrial Models Augmented with Electrophysiological Structures
- Introduction
- Materials and Methods
- Wall Thickness from MR-Data
- Atlas Mesh Generation
- Model Based Segmentation of the Atrial Endocardium
- Registration of the Atlas Mesh with Patient Images
- Results
- Discussion and Conclusion
- References
- Image Analysis
- Construction of Left Ventricle 3D Shape Atlas from Cardiac MRI
- Introduction
- Methods
- Algorithm Framework
- Geometry Processing
- Shape Registration and Shape Statistics
- Experiments
- Conclusions
- References
- Simulation of Diffusion Anisotropy in DTI for Virtual Cardiac Fiber Structure
- Introduction
- Method
- VCFS Model
- Diffusion MRI Simulation Theory
- Results and Discussion
- Monte Carlo Simulation of the Restricted Diffusion
- Simulation of VCFS
- DTI Simulation and Anisotropy Analysis
- Conclusion
- References
- On the Estimation of Transmural Myocardial Shear by Means of MRI Tagging
- Introduction
- Materials and Methods
- MRIT Acquisitions and Bandpass Filtering
- LV Motion Tracking with SinMod
- Lagrangian Shear Strain in Synthetic and Acquired Images
- Rotation and Shear Estimated with 16 Markers
- Results
- Discussion and Conclusion
- References
- Multi-frame Radial Basis Functions to Combine Shape and Speckle Tracking for Cardiac Deformation Analysis in Echocardiography
- Introduction
- Methods
- Shape Tracking Methods
- Speckle Tracking Methods
- Combined Method with RBFs
- Results
- Conclusion
- References
- Functional Imaging and Modeling
- Monitoring Treatment Outcome: A Visualization Prototype for Left Ventricular Transformation
- Introduction
- Computation of Left Ventricular Transformation
- Clinical Example
- Discussion
- References
- An Ultrasound-Driven Kinematic Model of the Heart That Enforces Local Incompressibility
- Introduction
- Methods
- Model Formulation
- Mouse Heart Imaging and Motion Estimates
- Optimization of Model Parameters
- Results
- Conclusion
- References
- Driving Dynamic Cardiac Model Adaptation with MR-Tagging Displacement Information
- Introduction
- Dynamic DET Model
- Model Main Equations
- Algorithm Implementation
- A Priori Information Applied to the Model
- Payne's Method for Prescribed Displacement
- MR-Tagging Data
- Method Evaluation Protocol
- Simulated MR-Tagging Sequences
- Study of Motion Prescription onto the Model
- The Case of Noisy Motion Data
- Global vs. Local Absence of Data
- In Vivo Data
- Discussion
- Conclusion
- References
- Towards Patient Specific Catheter Selection: Computation of Aortic Geometry Based on Fused MRI Data
- Introduction
- Material and Methods
- Whole Aorta Segmentation
- Coronary Artery Ostia Segmentation
- Geometrical Parameter Estimation
- Results
- Discussion and Conclusion
- References
- Oral Session 2: Image Analysis
- 4D Cardiac Reconstruction Using High Resolution CT Images
- Introduction
- Methodology
- Model Initialization
- Deformable Model Based Segmentation
- Interpolation
- Results and Validation
- Conclusion
- References
- 3D Fusion Echocardiography Improves Transoeosphageal LV Assessment
- Automatic Segmentation of Different Pathologies from Cardiac Cine MRI Using Registration and Multiple Component EM Estimation
- Introduction
- Methods
- Initial Atlas-Based Segmentation of the Heart
- Multi-component EM Estimation
- Segmentation of the Epi- and Endocardial Surfaces
- Results
- Discussion and Conclusion
- References
- Statistical Analysis of the Human Cardiac Fiber Architecture from DT-MRI
- Introduction
- Materials and Method
- Data Acquisition
- Segmentation
- Registration and Atlas Construction
- Statistical Analysis
- Results
- Fiber Variability
- Variability across Myocardial Segments
- Conclusion
- References
- Morphological Classification: Application to Cardiac MRI of Tetralogy of Fallot
- Introduction
- Method
- Feature Extraction
- Dimensionality Reduction
- Non-linear SVM
- Experiment
- Features
- Classification Accuracy
- Group Comparisons via Voxel-Based Analysis
- Conclusion
- References
- Oral Session 3: Functional Imaging and Modeling
- Cardiac MRI Intervention and Diagnosis via Deformable Collaborative Tracking
- Introduction
- Methodology
- Collaborative Tracking
- Deformed Region Computation
- Experimentation
- Collaborative versus MIL Tracking in Interventional MRI
- Surface Area Computation
- Conclusion
- References
- A 3D MRI-Based Cardiac Computer Model to Study Arrhythmia and Its In-vivo Experimental Validation
- Introduction
- Methodology
- Electrophysiology Study
- Construction of the 3D MRI-Based Computer Model of the Heart
- Mathematical Model
- Results
- Assessment of VT Inducibility in the EP Study
- Assessment of VT Inducibility in the 3D MR Image-Based Model
- Discussion and Future Work
- References
- An Automated Segmentation and Classification Framework for CT-Based Myocardial Perfusion Imaging for Detecting Myocardial Perfusion Defect
- Introduction
- Methodology
- CT Perfusion Imaging Protocol
- LV Segmentation in 3D
- Segmental Intensity Profile
- Ischemia Classification Using Linear Discriminant Analysis
- Experiments and Results
- Myocardial Segmentation
- Visual and Quantitative Assessment of CT Perfusion Image
- Discussion and Conclusion
- References
- Modeling Mitral Valve Leaflets from Three-Dimensional Ultrasound
- Introduction
- Methods and Materials
- Algorithm Summary and Components
- Constructing the Search Space
- Estimating an Extended Leaflet Surface
- Trimming an Extended Leaflet Surface
- Redefining the Search Space Axis
- Refining an Extended Leaflet Surface
- Mesh Generation
- Performance and Validation
- Discussion
- References
- Modeling Atrial Fiber Orientation in Patient-Specific Geometries: A Semi-automatic Rule-Based Approach
- Introduction
- Methods
- Patient-Specific Atrial Models
- Tissue Classification and Fiber Generation
- Electrophysiological Simulations
- Results
- Fiber Orientation and Tissue Classification
- Influence of Atrial Anisotropy on Excitation Sequence
- Discussion and Conclusion
- References
- Anisotropic Mass-Spring Method Accurately Simulates Mitral Valve Closure from Image-Based Models
- Introduction
- Methods
- Results
- Discussion
- Conclusion
- References
- Poster Session 2
- In Silico Analysis of the Impact of Transmural Myocardial Infarction on Cardiac Mechanical Dynamics for the 17 AHA Segments
- Introduction
- Methods
- Electrophysiological Modeling
- Elastomechanical Modeling
- Modeling of Transmural Infarctions in 17 AHA Segments
- Results
- Discussion and Future Work
- References
- Automatic Delineation of Left and Right Ventricles in Cardiac MRI Sequences Using a Joint Ventricular Model
- Introduction
- Methodology
- Joint Anatomy Model
- Learning-Based Model Fitting
- Dynamics Extraction
- Experiments
- Conclusions
- References
- Simulating Drug-Induced Effects on the Heart: From Ion Channel to Body Surface Electrocardiogram
- Introduction
- Methods
- 3D Anatomical Model of the Human Body
- Electrical Model
- Dofetilide Model
- Numerical Implementation
- Results
- Conclusions
- References
- Slice-Based Combination of Rest and Dobutamine-Stress Cardiac MRI Using a Statistical Motion Model to Identify Myocardial Infarction: Validation against Contrast-Enhanced MRI
- Introduction
- Methodology
- Experimental Results
- Discussion
- References
- Shape Analysis of the Left Ventricular Endocardial Surface and Its Application in Detecting Coronary Artery Disease
- Introduction
- MDCT Image Segmentation and Ventricular Shape Analysis
- Left Ventricle Segmentation and Meshing
- Shape Description
- Data Preparation
- Experimental Results
- Segmentation Results
- Shape Description Results
- Classification Accuracy
- Disccussion and Conclusions
- References
- Recovering Endocardial Walls from 3D TEE
- Introduction
- 3D Level Sets
- Inhibition Function
- Experiments
- Conclusions
- References
- Regionally Optimised Mathematical Models of Cardiac Myocyte Orientation in Rat Hearts
- Introduction
- Aims and Contributions
- Methods
- Sample Preparation and Image Aquisition
- Segmentation
- Separation of Left and Right Ventricles
- Regional Analysis
- Extended Mathematical Model
- Estimation of Optimal Parameters for the Mathematical Method
- Results
- Discussion
- References
- Mapping Contact Force during Catheter Ablation for the Treatment of Atrial Fibrillation: New Insights into Ablation Therapy
- Trials on Tissue Contractility Estimation from Cardiac Cine MRI Using a Biomechanical Heart Model
- Introduction
- Experimental Data and Direct Modeling
- Experimental Data
- Anatomical Model
- Biophysical Model
- Regional Contractility Estimation Using Data Assimilation
- Data Assimilation Methodology
- Estimation Using Segmented Cine MRI
- Estimation Results
- Discussion
- Conclusion and Perspectives
- References
- Real-Time Cardiac MR Anatomy and Dyssynchrony Overlay for Guidance of Cardiac Resynchronization Therapy Procedures: Clinical Results Update
- Parameter Identification in Cardiac Electrophysiology Using Proper Orthogonal Decomposition Method
- Introduction
- Methods
- Resolution of the Direct Problem
- Optimization Method
- POD Reduced-Order Modelling
- Results
- Two Illustrative Examples of POD Simulations
- Identification of Two Ionic Parameters
- Identification of the Initial Stimulation
- Discussion and Conclusion
- References
- Are Robotic-Assisted Catheter Ablation Lesions Different from Standard Catheter Ablation in Paroxysmal AF Patients? : Novel CMRI Findings Made Possible with Semi-automatic 3-D Visualisation
- MagnetoHemoDynamics Effect on Electrocardiograms
- Introduction
- Method
- Results
- Discussion and Conclusion
- References
- A Hybrid Method for Automatic Anatomical Variant Detection and Segmentation
- Introduction
- Method
- A Three Step Procedure
- Generation of the Model Data Base
- Detection of the Anatomical Variation
- Results
- Conclusion
- References
- Patient-Specific Model of Left Heart Anatomy, Dynamics and Hemodynamics from 4D TEE: A First Validation Study
- Introduction
- Patient-Specific Anatomy and Dynamics Computation
- Patient-Specific Hemodynamics Computation
- Validation Methodology
- Results
- Conclusion
- References
- Oral Session 4: Image Analysis
- Cardiac Motion Estimation from 3D Echocardiography with Spatiotemporal Regularization
- Introduction
- Method
- Deformation Model
- Similarity Metric
- Spatiotemporal Regularization
- Optimization
- Deformation Analysis
- Implementation
- Data and Experiment
- Result and Discussion
- Conclusion
- References
- Order Statistic Based Cardiac Boundary Detection in 3D+t Echocardiograms
- Introduction
- The Order Statistic Based Boundary Detector
- Segmentation of 3D+t Echocardiographic Images
- Results
- Conclusion
- References
- A Framework Combining Multi-sequence MRI for Fully Automated Quantitative Analysis of Cardiac Global And Regional Functions
- Introduction
- Method
- Motion and Shift Correction
- Multiple Image Registration for Segmentation Propagation
- Serial Registration for Cardiac Motion Tracking
- Cardiac Functional Analysis
- Experiment
- Conclusion
- References
- Multiview Diffeomorphic Registration for Motion and Strain Estimation from 3D Ultrasound Sequences
- Introduction
- Methods
- Experiments
- Strain Accuracy on Simulated US Data
- Strain Quantification in Healthy Volunteers
- Conclusions and Future Work
- References
- Pyramid Histograms of Motion Context with Application to Angiogram Video Classification
- Introduction
- Pre-processing of the Angiogram Sequence
- Representing Shape and Motion in Angiography Frames
- Motion Feature Representation
- Capturing Local Motion with ``motion context
- Combining Shape and Motion
- Experimental Results
- Summary
- References
- Oral Session 5: Cardiac Mechanics, Cardiac Electrophysiology
- An Automatic Data Assimilation Framework for Patient-Specific Myocardial Mechanical Parameter Estimation
- Introduction
- Material and Methods
- Clinical Measurements
- Myocardial Motion Tracking
- Dynamic Mesh Personalization
- Mechanical Simulation
- Identification of Myocardial Passive Constitutive Parameters
- Results
- Dynamic Meshing
- Mechanical Property Estimation
- Discussion
- References
- Left-Ventricular Shape Determines Intramyocardial Stroke Work Distribution
- Introduction
- Methods
- Variation in Left-Ventricular Shape
- Mechanics of the Myocardial Wall
- Depolarization Propagation
- Numerical Implementation
- Simulations
- Results
- Discussion
- Physiological Implications
- Limitations
- Conclusion
- References
- Constitutive Parameter Estimation Methodology Using Tagged-MRI Data
- Introduction
- Data Assimilation Principles
- Model
- Information Extraction from the Measurements
- Tagged-MRI Data Assimilation
- Definition of the Observation Operator
- Filter Formulation
- Parameter Estimation
- Estimation Results with Synthetic Data
- Reference Model Based on Experimental Data
- Generation of Synthetic Tags from the Model
- Estimation Results
- Concluding Remarks
- References
- Sensitivity Analysis of Mesh Warping and Subsampling Strategies for Generating Large Scale Electrophysiological Simulation Data
- Introduction
- Methods
- Experiments and Results
- Data
- Volumetric Mesh Differences
- Simulation Result Differences
- Discussion and Conclusions
- References
- Effect of Scar Development on Fast Electrophysiological Models of the Human Heart: In-Silico Study on Atlas-Based Virtual Populations
- Introduction
- Methods
- Modeling Infarction
- Modeling Fast Cardiac Conduction System of Purkinje
- Electrophysiological Models
- Virtual and Real Populations
- Results and Discussions
- Conclusions
- References
- Author Index
