Membrane Microdomain Signaling
Lipid Rafts in Biology and Medicine
1st Edition
Published on 27. October 2007
X, 214 pages
978-1-59259-803-8 (ISBN)
Description
Cutting-edge articles review our current understanding of lipid microdomain signaling mechanisms and their physiological and pathological importance. The book describes the role of lipid rafts in learning, memory, and cancer, presents the emerging evidence that lipid rafts play critical roles in signaling pathways and the regulation of synaptic function in the nervous system, and shows how alterations in lipid raft metabolism are implicated in the pathogenesis of neurodegenerative disorders. Techniques are also described for the isolation of lipid rafts, the analysis of the lipid and protein components of lipid rafts, the imaging of lipid rafts in living cells, and the analysis of signal transduction in lipid rafts.
Reviews / Votes
"...a good acquisition for general medical and neuroscience libraries." - Doody's Health Science Book Review JournalMore details
Other editions
Additional editions
Book
10/2004
Humana Press Inc.
€106.99
Shipment within 15-20 days
Content
From Intramolecular Asymmetries to Raft Assemblies.- Regulatory Aspects of Membrane Microdomain (Raft) Dynamics in Live Cells.- Lipid Raft Membrane Skeletons.- Role of Cholesterol in Membrane Microdomain Signaling.- Raft Lipid Metabolism in Relation to Alkyl-Lysophospholipid-Induced Apoptosis.- The Role of Lipid Rafts in Signal Transduction and Synaptic Plasticity of Neural Cells.- Role of Rafts in Virus Fusion and Budding.- Alterations in Raft Lipid Metabolism in Aging and Neurodegenerative Disorders.- Caveolin and Cancer.- Dietary Modulation of Lipid Rafts.
