
Focus on Systems Theory Research
Description
Alles über E-Books | Antworten auf Fragen rund um E-Books, Kopierschutz und Dateiformate finden Sie in unserem Info- & Hilfebereich.
More details
Other editions
Additional editions

Content
- Intro
- Contents
- Preface
- Chapter 1
- Biases in the Process of Designing a System
- Abstract
- 1. Introduction
- 1.1. Mesarovic and Takahara's General Systems Theory
- 1.2. Systems Engineering
- 1.3. Klir's Architecture of Systems Problem Solving
- 1.4. Van Gigch's Metamodeling
- 1.5. Churchman's Design of Inquiring Systems
- 1.6. Jackson's Systems Paradigms
- 1.7. Summary of the Selected Approaches to System Design
- 2. Some Basic Notions and Some Immediate Consequences
- 2.1. Definition of Core Notions
- 2.2. Some Consequences Derived from the Definition of Core Notions
- 3. Outline of the Developed Approach to System Design
- 4. The Core Context for System Design
- 5. The Material Base for System Design
- 5.1. The Material Needs for System Design
- 5.2. The Sources of the Material Base for the System Design
- 6. The Goal-Setting Process
- 6.1. The Options for Goal-Setting
- 6.2. Contexts of Goal-Setting and Resulting Biases Influencing the Design Process
- 6.3. Goal-Setting
- 6.4. Summary: The Goal-Setting Process
- 7. The Prerequisites of System Design
- 7.1. A Priori Knowledge
- 7.2. From A Priori Knowledge to Preliminary Knowledge
- 7.3. The Preliminary Knowledge of the System Designer and Its Necessary Scope
- 8. The Core Process of Designing a System: From the Prerequisites and Goal-Values via Preliminary Knowledge to the Final Design
- 8.1. The Core Process of System Design: From Elements and Relations via Subsystems to a Complete System Design
- 8.1.1. Assumptions
- 8.1.2. Selecting Elements and Relations
- 8.1.3. Intermediate Evaluation
- 8.2. From a Complete Design to the Final Design or When Is a System Design 'Good Enough'?
- 8.3. A Byproduct: An Increase in the Preliminary Knowledge of the System Designer
- 8.4. Redesigning a System
- 8.5. Summary of the Core Design Process
- 9. Putting a System Design in a Wider Context
- Summary and Conclusion
- References
- Chapter 2
- Mathematical Theory of Reliability and Biological Robustness: Reliable Systems from Unreliable Elements
- Abstract
- Introduction: Historical Synopsis
- Basic Terms and Ideas
- Reliability of Enzymes
- Reliability Versus Mortality
- Free-Radical Timer of Aging: Reliability-Theory Standpoint
- Antioxidants: Systems Reliability Standpoint
- Conclusion
- Acknowledgment
- References
- Biographical Sketch
- Chapter 3
- Quantum Models of Complex Systems
- Abstract
- Introduction
- Information Circuits
- Information Gate
- Professor-Student Information Model
- Information Dynamic
- Quantum Models
- Wave Probabilities
- Quantum Information Gate
- Wave Information Dynamic
- Features of Quantum Models
- Interference
- Mass-Parallelism
- Complexity Reduction
- Information Resonance
- Advanced Physical-Information Analogies
- Information Memelements
- Electric - Information Analogies
- Magnetic - Information Analogies
- Discussion
- Conclusion
- Acknowledgment
- References
- Model-Order Reduction with H2/H8 Performance
- Chapter 5
- Systems Thinking in Health Care: From Theory to Implementation
- Abstract
- Introduction
- Systems and Systems Thinking
- Systems
- Systems Thinking
- Systems Theory
- General Systems Theory (GST)
- Complex Adaptive Systems (CAS)
- Implementation of Systems Thinking
- Continuous Quality Improvement through Accreditation and Quality Measurement/Reporting Systems
- The Cessation of Repeated Scabies Outbreaks in a Respiratory Care Ward
- Conclusion
- References
- About the Authors
- Chapter 6
- Applications of Genome-Scale Metabolic Models and Data Integration in Systems Medicine
- Abstract
- Introduction
- Basic Concepts
- Metabolic Model Reconstruction Approaches
- The History of Publically Available Generic Human Genome-Scale Models
- Constraints-Based Modeling Approach
- Available Human Objective Function
- Using GEMs as Scaffolds for Multi Omics Data Integration
- Stratification of Methods to Integrate Transcriptomic Data into GEMs
- Application of GEMs in Systems Medicine
- Discussion and Challenges
- References
- Chapter 7
- Reality is Hierarchically Organized: The Recursive Foundations of Living Systems and Beyond
- Abstract
- Introduction
- Defining Hierarchical Recursive Organization
- Self-Organization in Systems Theory and Cybernetics
- Emergent Regulatory Organization
- The Problem of Biological Self-Organization
- Autopoiesis and Structural Coupling
- Markov Blankets and Living Systems
- Friston's Free Energy Principle (FEP)
- Hierarchical Organization in Living Systems
- Hierarchies of Organization in the Brain
- How Evolution Entrains the FEP
- Variational Neuroethology
- How Social Interaction and Culture Come to Regulate Living Systems
- Interpersonal Synchrony
- Conclusion
- References
- Chapter 8
- New Directions in Occupational Roadway Safety Grounded in Complex Systems Theory and Simulation Modeling
- Abstract
- Introduction
- Conventional Theory and Methodology in Occupational Roadway Safety
- Conventional Theory in Occupational Roadway Safety
- Conventional Methodology in Occupational Roadway Safety
- Limitations of Conventional Approaches in Occupational Roadway Safety
- A Shift towards Complex Systems Theory in Occupational Roadway Safety
- Complex Systems Theory in Occupational Roadway Safety
- A Shift towards Complex Systems Methodology
- in Occupational Roadway Safety
- Modeling of Occupational Roadway Safety Systems
- Modeling of Complex Systems: Computational Modeling and Simulation in Occupational Roadway Safety
- Conclusion
- Moving Forward: Adopting a Complex Systems Paradigm in Occupational Roadway Safety
- References
- Chapter 9
- The Part-Systems Continuum in Medicine
- Abstract
- 1. Introduction
- 2. Reductionism versus Emergentism
- 3. Reductionist Research Program in Medicine
- Subsequent Explanations on Reductive Level Fail
- CFTR-Mutations Favor Growth of Microorganisms
- Alterations of the Microbial Pathogens
- Biofilms and Inflammation
- Broadening the Reduction Basis
- External Factors in Complex Diseases
- 4. General Appearance of Emergence
- Emergent Principles
- 5. System and Its Parts - Implications in Medicine
- References
- Chapter 10
- Systems Theory and the Cerebral Cortex
- Abstract
- Introduction
- The Triune Brain
- Cerebral Cortex
- Minicolumns
- Laws of Conservation
- References
- Chapter 11
- From Quorum Sensing to Dynome through Mitochondria
- Abstract
- History
- Origins, Evolutionary Timeline and Age Clock
- Nuclear DNA vs Mt DNA
- Structure and Function
- The Powerplant of the Cell
- Immunology
- Plant vs. Animal World Mitochondrion
- Fission and Fusion
- Calcium (Ca2+)
- Nitric Oxide (NO)
- ROS Reactive Oxygen Species
- From Hunter -Gather Feeding Condition to "Fast Food" Eating Habits
- Ageing
- Apoptosis
- Disease
- Rare Mitochondrial Disorders
- Ischemic Glutamate Release
- Mitocondria as Informational Hub between Molecule to Contectom and Dynom
- Heat and Light Production
- Refringence
- Biophotons
- From Connectom to Dynom
- Conclusion
- References
- Chapter 12
- The Nutrition System and the Brain
- Abstract
- 1. Introduction
- 1.1. History of Human Nutrition
- 1.2. Nutrition
- 1.2.1. Macronutrients vs. Micronutrients.
- 1.2.2. Animal vs. Plant Nutrition
- 1.3. Processed Foods
- 2. The Gut-Brain Connection and the Connectome
- 2.2.1. The Enteric Nervous System
- 2.2.2. The Gut-Brain Axis
- 2.2.3. The Vagus Nerve as a Link between Gut and Brain
- 2.2.4. The Brain-Gut Connectome
- Gut Connectome
- Neurochemical Connectome
- 3. The Interplay between Nutrition, Microbiome, Metabolism and Immune System
- 3.1. Nutrition vs. Immune System
- 3.2 Nutrition vs. Microbiome
- Role of the Microbiome in Shaping a Healthy Immune System
- 3.3 Nutrition vs. Metabolism
- 3.4. The Link between Nutrition, Metabolism, Immune System and Microbiome
- 4. Nutrition and Reward
- 4.1. Reinforced Consumption of Palatable Food or Obesity
- 4.2. Motivated and Reinforced Starving or Anorexia Nervosa
- 5. Nutrition and Disease
- Gut Microbiome Impacts Human Brain Health
- 5.1. Malnutrition
- 5.2. Cancer
- 5.3. Mental Disorders
- 5.4. Metabolic Syndrome
- 6. Conclusion
- 6.1. Future of Nutrition
- 6.1.1. Mathematical and Computational Modeling
- 6.2. Challenges of Nutrition in the Context of Increased Population in 2050
- References
- Chapter 13
- A Modular Approach to the Organization of Brain Functions
- Abstract
- 1. Introduction
- 2. Anatomical Substrate of Brain Function: From Microcircuitry to Connectome
- 2.1. Cortical Microcircuitry
- 2.2. Brain's Connectome
- 2.3. Functional Connectomics: Default Mode vs. Executive Control Networks
- 2.4. Modularity
- 3. Modular Substrate of Brain Functions: From Microcircuitry to Macro-Networks
- 3.1. Prefrontal Cortex Is an Integrative Hub of the Connectome
- 3.1.1. Prefrontal Cortical Connections
- 3.1.2. Prefrontal-Parietal Connections
- 3.1.3. Prefrontal-Temporal/Hippocampal Connections
- 3.1.4. Cortico-Striatal and Thalamo-Cortical Connections
- 3.1.5. Callosal Connections
- 3.1.6. Prefrontal-Brainstem Connection
- 3.2. Noninvasive Neuromodulation of the Connectome
- 4. Emergence of Brain Functions in the Prefrontal Cortical Hub
- 4.1. Cognitive Functions
- 4.1.1. Perception to Action Cycle
- 4.1.2. Memory Connectome
- 4.1.3. Decision Making and Executive Control
- 4.2. Emergence of Brain Function and the Power of Two Permutation Logic
- 5. Brain Disorders and the Connectome
- 5.1. Autism Spectrum Disorder
- 5.2. Alzheimer Disease
- Conclusion
- References
- About the Editors
- Index
- Blank Page
System requirements
File format: PDF
Copy-Protection: Adobe-DRM (Digital Rights Management)
System requirements:
- Computer (Windows; MacOS X; Linux): Install the free reader Adobe Digital Editions prior to download (see eBook Help).
- Tablet/smartphone (Android; iOS): Install the free app Adobe Digital Editions or the app PocketBook before downloading (see eBook Help).
- E-reader: Bookeen, Kobo, Pocketbook, Sony, Tolino and many more (only limited: Kindle).
The file format PDF always displays a book page identically on any hardware. This makes PDF suitable for complex layouts such as those used in textbooks and reference books (images, tables, columns, footnotes). Unfortunately, on the small screens of e-readers or smartphones, PDFs are rather annoying, requiring too much scrolling.
This eBook uses Adobe-DRM, a „hard” copy protection. If the necessary requirements are not met, unfortunately you will not be able to open the eBook. You will therefore need to prepare your reading hardware before downloading.
Please note: We strongly recommend that you authorise using your personal Adobe ID after installation of any reading software.
For more information, see our eBook Help page.