
Handbook of Statistical Bioinformatics
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"This book puts together a nice collection of statistical methods covering a wide range of research topics in computational biology. . I can recommend the book as an overview on methods applied in computational biology for readers already experienced in basic computational statistics. Especially readers interested in systems biology topics will find a comprehensive summary of methods." (Marc Zapatka, Biometrical Journal, Vol. 55 (4), 2013)
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Content
I: Accuracy Assessment of Consensus Sequence from Shotgun Sequencing.- Statistical and Computational Studies on Alternative Splicing.- Using Sequence Information to Predict TF-DNA Binding.- Computational Promoter Prediction in a Vertebrate Genome.- Discovering Influential Variables: A General Computer Intensive Method for Common Genetic Disorders.- STORMSeq: A Method for Ranking Regulatory Sequences by Integrating Experimental Datasets with Diverse Computational Predictions.- Mixture Tree Construction and Its Applications.- II: Experimental Designs and ANOVA for Microarray Data.- MAQC and Cross Platform Analysis of Microarray Data.- A Survey of Classification Techniques for Microarray Analysis.- Statistical Analysis of Single Nucleotide Polymorphism Microarrays in Cancer Studies.- Computational Analysis of ChIP-chip Data.- eQTL Mapping for Functional Classes of Saccharomyces Cerevisiae Genes with Multivariate Sparse Partial Least Squares Regression.- Analysis of Time Course Data.- III: Kernel Methods in Bioinformatics.- Graph Classification Methods in Chemoinformatics.- Hidden Markov Random Field Models for Network-based Analysis of Genomic Data.- Review of Weighted Gene Coexpression Network Analysis.- Liquid Association.- Boolean Networks.- Protein Interaction Networks: Protein Domain Interaction and Protein Function Prediction.- Regulatory Networks.- Inferring Signaling and Gene Regulatory Network from Genetic and Genomic Information.- Computational Drug Target Pathway Discovery: A Bayesian Network Approach.- Cancer Systems Biology.- Comparative Genomics and Molecular Evolution.- Robust Control of Immune Systems under Noises: Stochastic Game Approach.
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