Logic Synthesis for Genetic Diseases
Modeling Disease Behavior Using Boolean Networks
1st Edition
Published on 31. October 2013
XXI, 100 pages
978-1-4614-9429-4 (ISBN)
Description
This book brings to bear a body of logic synthesis techniques, in order to contribute to the analysis and control of Boolean Networks (BN) for modeling genetic diseases such as cancer. The authors provide several VLSI logic techniques to model the genetic disease behavior as a BN, with powerful implicit enumeration techniques. Coverage also includes techniques from VLSI testing to control a faulty BN, transforming its behavior to a healthy BN, potentially aiding in efforts to find the best candidates for treatment of genetic diseases.
More details
Series
Language
English
Place of publication
New York
United States
Publishing group
Springer US
Target group
Professional and scholarly
Product notice
Reflowable
Illustrations
XXI, 100 p. 28 illus., 8 illus. in color.
File size
1,98 MB
ISBN-13
978-1-4614-9429-4 (9781461494294)
DOI
10.1007/978-1-4614-9429-4
Schweitzer Classification
Other editions
Additional editions
Pey-Chang Kent Lin | Sunil P. Khatri
Logic Synthesis for Genetic Diseases
Modeling Disease Behavior Using Boolean Networks
Book
11/2013
Springer
€106.99
Shipment within 15-20 days
Content
Introduction.- Part I Inference of Gene Regulatory Networks.- Predictor Set Inference using SAT.- Determining Gene Function in Boolean Networks using SAT.- Predictor Ranking using Modified Zhegalkin Functions.- Part II Intervention of Gene Regulatory Networks.- ATPG for Cancer Therapy.- Summary and Future Work.
