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Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation, Second Edition, provides comprehensive coverage of the challenges and opportunities facing the therapeutic implications of pharmacogenomics from academic, regulatory, pharmaceutical, socio-ethical and economic perspectives. While emphasis is on the limitations in moving the science into drug development and direct therapeutic applications, this book also focuses on clinical areas with successful applications and important initiatives that have the ability to further advance the discipline. New chapters cover important topics such as pharmacogenomic data technologies, clinical testing strategies, cost-effectiveness, and pharmacogenomic education and practice guidelines. The importance of ethnicity is also discussed, which highlights phar,acogenomic diversity across Latin American populations.With chapters written by interdisciplinary experts and insights into the future direction of the field, this book is an indispensable resource for academic and industry scientists, graduate students and clinicians engaged in pharmacogenomics research and therapeutic implementation.
- Provides viewpoints that focus on the scientific and translational challenges and opportunities associated with advancing the field of pharmacogenomics
- Highlights progress in both the research and clinical areas of pharmacogenomics, as well as relevant implementation experience, challenges, and perspectives on direct-to-consumer genetic testing
- Includes, where applicable, discussion points, review questions, and cases for self-assessment purposes and to facilitate in-depth discussion
Edition
Language
Place of publication
Publishing group
Elsevier Science & Techn.
ISBN-13
978-0-12-812627-1 (9780128126271)
Schweitzer Classification
1. Principles of Pharmacogenomics: Pharmacokinetic, Pharmacodynamic, and Clinical Implications2. Governmental and Academic Efforts to Advance the Field of Pharmacogenomics3. Incorporating Pharmacogenomics in Drug Development: Industry and Regulatory Perspectives4. Translating Pharmacogenomic Research to Therapeutic Potentials5. Pharmacogenomics in Cancer Therapeutics6. Pharmacogenomics in Cardiovascular Diseases7. Pharmacogenomics in Psychiatry Disorders8. Role of Pharmacogenomics in HIV Infection9. Role of Pharmacogenomics in Diabetes10. A Look to the Future: Pharmacogenomics, Pharmacoepigenomics, and System Biology - Data Technologies of Today and Tomorrow11. The Importance of Ethnicity Definitions and Pharmacogenomics in Ethnobridging and Pharmacovigilance12. Pharmacogenomics in Latin American Population13. Reactive, Point-of-Care, Pre-emptive and Direct-to-Consumer Pharmacogenomic Testing14. Economic Evaluation of Pharmacogenomic Testing: Lessons from Psychiatric Pharmacogenomics15. Pharmacogenomics Education and Clinical Practice Guidelines