Current Topics in Cellular Regulation

ContributorsPoly ADP-Ribosylation of Protein I. Perspectives and Summary II. Poly(ADP-Ribose): Historical Aspects and Characterization III. Quantification of Poly(ADP-Ribose) IV. Poly(ADP-Ribose) Synthetase V. Degradation of Poly(ADP-Ribose) VI. Physiological Functions of Poly(ADP-Ribose) ReferencesThe Control of the Rate of Initiation of Eukaryotic Protein Synthesis I. Introduction II. Purification and Characterization III. The Mode of Action of the Regulatory Factor, eRF IV. The Effect of HRI V. Complex Formation Between eIF-2 and eRF VI. Discussion ReferencesStructures and Functions of Lysosomal Thiol Proteinases and Their Endogenous Inhibitor I. Introduction II. Properties of Lysosomal Thiol Proteinases III. Structures of Lysosomal Thiol Proteinases IV. Control of Lysosomal Thiol Proteinases V. Endogenous Thiol Proteinase Inhibitor VI. Functions of Lysosomal Thiol Proteinases VII. Concluding Remarks ReferencesRegulation, Genetics, and Properties of Adenylosuccinate Synthetase: A Review I. Introduction II. Measurement of Enzyme Activity III. Isolation and Properties IV The Isozymes of Adenylosuccinate Synthetase V. Substrate Specificity VI. Inhibitors VII. Mechanism of Action VIII. Adenylosuccinate Synthetase Regulation in E. coli IX. Regulation and Metabolic Roles of Eukaryotic Adenylosuccinate Synthetase X. Genetic Considerations ReferencesRegulation of Acetyl-CoA Carboxylase I. Introduction II. Allosteric Control Mechanism III. Covalent Modification Mechanism IV. Relationship Between Covalent Phosphorylation and the Quaternary Structure of Acetyl-CoA Carboxylase V. Regulation of Covalent Phosphorylation of Acetyl-CoA VI. Concluding Remarks ReferencesThe Evolutionary History of the Ornithine Cycle as a Determinant of Its Structure and Regulation I. Introduction II. Problematical Aspects of the Ornithine Cycle III. Evolutionary Origin of the Ornithine Cycle IV. Evaluation of the Postulated Evolutionary Relationships V. Conclusion ReferencesRegulatory Features of Seminal Vesicle Development and Function I. Introduction II. Occurrence and Functions of Seminal Vesicles III. Male Reproductive Tract Differentiation and the Molecular Biology of Steroid Hormone Action IV. Embryonic Differentiation of Seminal Vesicles V Hormonal Regulation of Adult Seminal Vesicle Growth and Secretory Functions VI. Formation and Functions of Vesicular Secretion Constituents VII. Participation of Vesicular Secretion Constituents in Semen Coagulation ReferencesIndexCumulative Contributors IndexContents of Previous Volumes