Current Topics in Cellular Regulation

List of ContributorsGuanosine 3',5'-Monophosphate-Dependent Protein Kinase I. Introduction II. Structure and Regulation of G-Kinase III. Kinetics and Thermodynamics of cGMP Binding to G-Kinase IV. G-Kinase Activity V. A Hypothesis Concerning the Structures of G-Kinase and A-Kinase ReferencesCalmodulin and Its Role in the Second-Messenger System I. Introduction II. General Background III. Activation of Cyclic Nucleotide Phosphodiesterase IV. Other Regulatory Activities V. Physiological Roles VI. Evolutionary Studies ReferencesPhosphofructokinase: Structure and Function I. Introduction II. Structural Properties III. Polymeric Forms of Phosphofructokinase IV. Ligand Binding to Phosphofructokinase V. Allosteric Kinetics VI. Cold Lability of Rabbit Muscle Phosphofructokinase VII. Mechanism of the Reaction VIII. Enzyme Modification IX. Ligand-Induced Conformational Changes X. Alternative Modes of Enzyme Regulation ReferencesGenetic Control of Pentose Phosphate Pathway Enzymes in Drosophila I. Introduction II. The Pathway III. The Structural Genes IV. Genetic Regulatory Effects V. Metabolic Regulatory Effects VI. Concluding Remarks ReferencesThe Regulation and Function of Ornithine Decarboxylase and of the Polyamines I. Introduction II. Discrepancies in the Interpretation of the ODC Assay III. Functions of Polyamines IV The "Metabolic State" of the Cell and the "External Setting V. The Experimental Systems VI. Mechanisms That Alter ODC Activity VII. The Dynamic State of Polyamines in the Normal and Pathologic State VIII. An Overview of ODC Regulation IX. Concluding Remarks ReferencesBiochemistry of Phagocyte Chemotaxis I. Introduction II. Comparison of Chemotaxis in Leukocytes and Other Cells III. Assay of Chemotaxis IV. The Chemoattractants: Sensing the Signal V. Transduction of the Chemotactic Signal VI. Effector Processes: Sustained Locomotion VII. Concluding Remarks ReferencesBiochemical Aspects of Neurosecretion: Neurophysin-Neurohypophyseal Hormone Complexes I. Introduction II. Neurohormones and Neurophysins: Structural Features III. Neurophysin-Neurohormone Complexes-In Vitro Studies IV. Neurophysin-Neurohormone Complexes-In Vivo Studies V. Concluding Remarks ReferencesSubject IndexCorrection to Volume 9Contents of Previous Volumes