Textbook of Diabetes
Description
Classic textbook providing diabetologists and endocrinologists with illustrated and clinically focused content on diabetes
Now in its sixth edition, the Textbook of Diabetes has established itself as the modern, international guide to diabetes. Sensibly organized and easy to navigate, with exceptional illustrations, the textbook hosts an unrivalled blend of clinical and scientific content. Written by highly experienced editors and international contributors all of whom have provided insight on new developments in diabetes care. These include the most recent guidelines from the European Association for the Study of Diabetes (EASD), the American Diabetes Association (ADA), Diabetes UK, and the National Institute for Health and Care Excellence (NICE) and information on the latest treatment modalities used around the world.
The textbook includes free access to the Wiley Digital Edition which provides easy-to-use searching across the book, the full reference list with web links, illustrations and photographs, and post-publication updates.
Sample topics covered in Textbook of Diabetes include:
* Diabetes in its historical and social context, covering the history of diabetes, past classification and diagnosis of diabetes and the global burden of diabetes
* Normal physiology, covering glucose homeostasis, islet function and insulin secretion, and
glucagon in islet and metabolic regulation
* Pathogenesis of diabetes, covering genetics of diabetes and obesity, autoimmune type 1 diabetes
and other disorders with type 1 diabetes phenotype
* Other types of diabetes, covering endocrine disorders that cause diabetes, pancreatic diseases and diabetes and drug-induced diabetes
Beautifully illustrated with a clinical focus, Textbook of Diabetes provides endocrinologists and diabetologists, both consultants/specialists and those in training, with a fresh and comprehensive clinical resource to consult time and time again. The text is also of value to specialist diabetes nurses and researchers in the field.
More details
Other editions
Additional editions
Persons
Richard I.G. Holt, Professor in Diabetes and Endocrinology, University of Southampton, UK and Honorary Consultant Physician, University Hospital Southampton NHS Foundation Trust. Professor Holt is also Chair of the EASD Committee for Clinical Affairs.
Allan Flyvbjerg, Former CEO at Steno Diabetes Center Copenhagen and Clinical Professor at University of Copenhagen, Denmark. Further, professor Flyvbjerg was President of the Danish Diabetes Association from 2000-2011 and is presently member of the Board of Directors of EASD, Chairman of the EASD Postgraduate Education Committee and Chairman of the Board of Directors of The Danish Diabetes and Endocrine Academy (DDEA).
Content
List of Contributors, viii
Preface, xv
List of Abbreviations, xvi
Part 1 Diabetes in its Historical and Social Context
1 The History of Diabetes Mellitus, 3
Robert B. Tattersall and David R. Matthews
2 Classification and Diagnosis of Diabetes, 22
Ambady Ramachandran, Chamukuttan Snehalatha, Arun Raghavan, and Arun Nanditha
3 The Global Burden of Diabetes, 28
Jessica L. Harding, Mary Beth Weber, and Jonathan E. Shaw
4 Epidemiology of Type 1 Diabetes, 41
Lars C. Stene and Jaakko Tuomilehto
5 Epidemiology of Type 2 Diabetes, 55
Ronald C.W. Ma and Peter C.Y. Tong
Part 2 Normal Physiology
6 Overview of Glucose Metabolism, 77
Richard I.G. Holt
7 Islet Function and Insulin Secretion, 84
Peter M. Jones and Shanta J. Persaud
8 Glucagon in Islet and Metabolic Regulation, 99
Jonathan E. Campbell and David A. D'Alessio
9 Mechanism of Insulin Action, 111
Morris F. White
10 Central Control of Glucose Homeostasis, 128
Kimberly M. Alonge, Kendra L. Francis, Nicole E. Richardson, and Michael W. Schwartz
11 Control of Body Weight: How and Why Do We Gain Weight Easier Than We Lose It?, 142
Janine Makaronidis and Rachel L. Batterham
Part 3 Pathogenesis of Diabetes
12 The Genetics of Diabetes, 157
Rashmi B. Prasad
13 Genetics of Obesity, 197
I. Sadaf Farooqi
14 Autoimmune Type 1 Diabetes, 203
Omar Akel and Ake Lernmark
15 Other Disorders with Type 1 Diabetes and Atypical Phenotypes, 216
Alice P.S. Kong, Elaine Y.K. Chow, Andrea O.Y. Luk, and Juliana C.N. Chan
16 Abnormalities of Insulin Secretion and ß-Cell Defects in Type 2 Diabetes, 225
Stefano Del Prato, Cristina Bianchi, and Giuseppe Daniele
17 Insulin Resistance in Type 2 Diabetes, 238
Michael Roden, Kitt Falk Petersen, and Gerald I. Shulman
18 Obesity and Diabetes, 250
Nick Finer
19 The Microbiome and Diabetes, 261
Amanda J. Cox, Nicholas P. West, and Allan W. Cripps
Part 4 Other Types of Diabetes
20 Monogenic Causes of Diabetes, 275
Brittany L. Resnick, Maggie H. Shepherd, and Andrew T. Hattersley
21 Drug-Induced Diabetes, 295
Charles D. Ponte and Devra K. Dang
22 Diabetes in Hypersecreting Endocrine Disorders, 304
Allan A. Vaag, Neil A. Hanley, and Caroline M. Kistorp
23 Pancreatic Disease and Diabetes, 319
Ranjit Unnikrishnan and Viswanathan Mohan
24 Clinical Presentations of Diabetes, 330
Ee Lin Lim and Roy Taylor
Part 5 Managing the Person with Diabetes
25 The Aims of Diabetes Care, 343
Katharine D. Barnard-Kelly and Richard I.G. Holt
26 Education to Empower the Person with Diabetes, 354
Ingrid Willaing and Michael Vallis
27 Dietary Management of Diabetes, 368
Nicola Guess
28 Physical Activities and Diabetes, 382
Emma J. Cockcroft and Robert C. Andrews
29 Monitoring Diabetes, 404
Emma English
30 Biomarkers and Precision Medicine in Diabetes, 414
Sok Cin Tye, Michele Provenzano, and Hiddo J.L. Heerspink
Part 6 Treatment of Diabetes
31 Insulin and Insulin Treatment, 431
Roman Vangoitsenhoven, Parth Narendran, and Chantal Mathieu
32 New Technologies for Glucose Monitoring, 444
Thomas Danne and Olga Kordonouri
33 New Technologies for Insulin Administration, 459
Hannah Forde and Pratik Choudhary
34 Whole Pancreas and Islet Cell Transplantation, 473
Braulio A. Marfil-Garza, Peter A. Senior, and A.M. James Shapiro
35 Oral Glucose-Lowering Agents, 492
Clifford J. Bailey and Andrew J. Krentz
36 Non-insulin Parenteral Therapies, 520
Tina Vilsboll, Mikkel Christensen, Andreas Andersen, and Filip K. Knop
37 How to Use Type 2 Diabetes Treatments in Clinical Practice, 534
Thomas Karagiannis, Aris Liakos, and Apostolos Tsapas
38 Weight Management and Metabolic Surgery, 551
Alexis Sudlow, Dimitri J. Pournaras, and Carel W. le Roux
39 In-Hospital Treatment and Surgery in People with Diabetes, 559
Ketan Dhatariya, Philip Newland-Jones, and Mayank Patel
40 Hypoglycaemia in Diabetes, 579
Ahmed Iqbal, Elaine Y.K. Chow, Timothy W. Jones, and Simon R. Heller
41 Acute Metabolic Complications of Diabetes: Diabetic Ketoacidosis and the Hyperosmolar Hyperglycaemic State in Adults, 602
Philip Newland-Jones, Mayank Patel, and Ketan Dhatariya
Part 7 Microvascular Complications in Diabetes
42 Pathogenesis of Microvascular Complications, 615
Allan Flyvbjerg
43 Diabetic Retinopathy, 629
Toke Bek
44 Diabetic Nephropathy, 640
Peter Rossing and Allan Flyvbjerg
45 Diabetic Neuropathy, 655
Shazli Azmi, Uazman Alam, and Rayaz A. Malik
Part 8 Macrovascular Complications in Diabetes
46 Pathogenesis of Macrovascular Complications in Diabetes, 681
Jakob A. Ostergaard, Tomasz J. Block, Sophia Dahm, Waheed Khan, and Karin A.M. Jandeleit-Dahm
47 Hypertension and Diabetes, 700
Peter M. Nilsson
48 Dyslipidaemia and Diabetes, 713
Adie Viljoen, Ahmed Handhle, and Anthony S. Wierzbicki
49 Ischaemic Heart Disease in Diabetes, 724
Michael Lehrke and Nikolaus Marx
50 Heart Failure and Diabetes, 732
Ambarish Pandey, Kershaw V. Patel, and Subodh Verma
51 Cerebrovascular Disease and Diabetes, 745
Colum F. Amory, Jesse Weinberger, and Travis S. Smith
52 Peripheral Vascular Disease, 755
Henrik H. Sillesen
Part 9 Other Complications of Diabetes
53 Foot Problems in People with Diabetes, 771
Frank L. Bowling, Keeley J. Foley, and Andrew J.M. Boulton
54 Sexual Function in Men and Women with Diabetes, 780
Kirsty Winkley, Camilla Kristensen, Jackie Fosbury, and David Price
55 Gastrointestinal Manifestations of Diabetes, 796
Michael Camilleri and Adil E. Bharucha
56 Diabetes and Oral Health, 810
Palle Holmstrup, Christian Damgaard, and Allan Flyvbjerg
57 Diabetes and Non-alcoholic Fatty Liver Disease, 820
Alessandro Mantovani, Giovanni Targher, and Christopher D. Byrne
58 The Skin in Diabetes, 838
Paul Devakar Yesudian
59 Bone and Rheumatic Disorders in Diabetes, 853
Andrew Grey and Nicola Dalbeth
60 Diabetes and Cancer: Risk, Outcomes, and Clinical Implications, 867
Ellena Badrick, Emily J. Gallagher, and Andrew G. Renehan
61 Diabetes and Infections, 878
Andrea O.Y. Luk and Clive S. Cockram
62 Sleep and Diabetes, 897
Sonya Deschênes, Amy McInerney, and Norbert Schmitz
Part 10 Psychosocial Aspects of Diabetes
63 Psychosocial and Behavioural Aspects of Diabetes, 907
Frans Pouwer and Jane Speight
64 Role of Cognitive Function in Managing People with Diabetes, 922
Tamsin Santos, Chelsea Baird, Sally Eastwood, Kerrie Shiell, and Joseph E. Ibrahim
65 Mental Disorders and Diabetes, 933
Najma Siddiqi, Marietta Stadler, and Richard I.G. Holt
66 Social Aspects of Diabetes, 956
Brian M. Frier and Mark W.J. Strachan
67 Social Determinants of Diabetes, 973
Keri F. Kirk, Gerald McKinley, Briana Mezuk, and Erica Spears
Part 11 Diabetes in Special Groups
68 Ethnic, Cultural, and Religious Aspects to the Management of Diabetes, 987
Wasim Hanif, Sarah N. Ali, and Vinod Patel
69 Diabetes in Childhood, 999
Jennifer M. Ikle, Ananta Addala, and David M. Maahs
70 Adolescence and Emerging Adulthood: Diabetesin Transition, 1019
Charlotte W. Chen and Lori M.B. Laffel
71 Diabetes in Pregnancy, 1034
David R. McCance and Laura Cassidy
72 Diabetes in Old Age, 1072
Ahmed H. Abdelhafiz and Alan J. Sinclair
73 Diabetes at the End of Life, 1085
Trisha Dunning and June James
Part 12 Delivery and Organization of Diabetes Care
74 The Role of the Multidisciplinary Team across Primary and Secondary Care, 1097
Samuel Seidu and Kamlesh Khunti
75 Models of Diabetes Care in Low-and Middle-Income Countries, 1107
David Beran, Sigiriya Aebischer Perone, and Maria Lazo-Porras
Part 13 Future Directions
76 Immunotherapies for Type 1 Diabetes, 1125
Jesper Johannesen and Flemming Pociot
77 Stem Cell Therapy in Diabetes, 1137
Angelo Avogaro and Gian Paolo Fadini
78 Gene Therapy for Diabetes, 1144
Veronica Jimenez and Fatima Bosch
79 Future Drug Treatments for Type 2 Diabetes, 1154
Clifford J. Bailey
Index, 1167
List of Contributors
Ahmed H. Abdelhafiz
Department of Elderly Medicine
Rotherham General Hospital
Rotherham, UK
Ananta Addala
Division of Endocrinology, Department of Pediatrics
Stanford University
Stanford, CA, USA
Omar Akel
Department of Clinical Sciences, Lund University CRC
Skåne University Hospital
Malmö, Sweden
Uazman Alam
Department of Cardiovascular and Metabolic
Medicine, Institute of Life Course and Medical
Sciences, University of Liverpool, Liverpool, UK
Sarah N. Ali
Department of Diabetes and Endocrinology
Royal Free London NHS Foundation Trust
London, UK
Kimberly M. Alonge
UW Medicine Diabetes Institute, Department of
Medicine
University of Washington
Seattle, WA, USA
Colum F. Amory
Albany Medical College
Albany, NY, USA
Andreas Andersen
University of Copenhagen
Copenhagen, Denmark
Robert C. Andrews
Faculty of Health & Life Science, Clinical and
Biomedical Sciences, University of Exeter, Exeter, UK
Department of Diabetes, Taunton and Somerset
NHS Foundation Trust, Taunton, UK
Angelo Avogaro
Department of Medicine
University of Padova
Padua, Italy
Shazli Azmi
Faculty of Biology, Medicine and Health
University of Manchester
Manchester, UK
Ellena Badrick
Division of Cancer Sciences
University of Manchester
Manchester, UK
Clifford J. Bailey
School of Life and Health Sciences
Aston University
Birmingham, UK
Chelsea Baird
Queen Elizabeth Centre, Ballarat Health Service and
Department of Forensic Medicine, Monash
University
Melbourne, Australia
Katharine D. Barnard-Kelly
Southern Health NHS Foundation Trust
Southampton, UK
Rachel L. Batterham
Centre for Obesity Research, Rayne Institute
Department of Medicine, University College London
University College London Hospital (UCLH)
Bariatric Centre for Weight Management and
Metabolic Surgery
National Institute of Health Research, UCLH
Biomedical Research Centre
London, UK
Toke Bek
Department of Ophthalmology
Aarhus University Hospital
Department of Clinical Medicine, Faculty of Health
Aarhus University
Aarhus, Denmark
David Beran
Division of Tropical and Humanitarian Medicine
University of Geneva and Geneva University
Hospitals
Faculty Diabetes Centre, Faculty of Medicine
University of Geneva
Geneva, Switzerland
Adil E. Bharucha
Clinical Enteric Neuroscience Translational and
Epidemiological Research (CENTER)
Division of Gastroenterology and Hepatology, Mayo
Clinic
Rochester, MN, USA
Cristina Bianchi
Department of Clinical and Experimental Medicine
University of Pisa
Pisa, Italy
Tomasz J. Block
Department of Diabetes, Central Clinical School
Monash University
Melbourne, Australia
Fatima Bosch
Center of Animal Biotechnology and Gene Therapy,
Department of Biochemistry and Molecular
Biology
University Autònoma de Barcelona
Barcelona, Spain
Centro de Investigación Biomédica en Red de
Diabetes y Enfermedades Metabólicas Asociadas
(CIBERDEM)
Madrid, Spain
Andrew J.M. Boulton
Department of Medicine, University of
Manchester and
Manchester Royal Infirmary
Manchester, UK
Miller School of Medicine
University of Miami
Miami, FL, USA
Frank L. Bowling
Department of Medicine, University of
Manchester and
Manchester Royal Infirmary
Manchester, UK
Miller School of Medicine
University of Miami
Miami, FL, USA
Christopher D. Byrne
Nutrition and Metabolism, Faculty of Medicine
University of Southampton
Southampton National Institute for Health and Care
Research Biomedical Research Centre
University Hospital Southampton, Southampton
General Hospital
Southampton, UK
Michael Camilleri
Clinical Enteric Neuroscience Translational and
Epidemiological Research (CENTER)
Division of Gastroenterology and Hepatology,
Mayo Clinic
Rochester, MN, USA
Jonathan E. Campbell
Department of Medicine, Division of
Endocrinology
Duke University
Durham, NC, USA
Laura Cassidy
Regional Centre for Endocrinology and Diabetes
Royal Victoria Hospital
Belfast, Northern Ireland
Juliana C.N. Chan
Department of Medicine and Therapeutics
Hong Kong Institute of Diabetes and Obesity
Li Ka Shing Institute of Health Sciences
The Chinese University of Hong Kong
Prince of Wales Hospital
Hong Kong, SAR, China
Charlotte W. Chen
Pediatric, Adolescent and Youth Adult Section
Joslin Diabetes Center, and Harvard Medical School
Boston, MA, USA
Pratik Choudhary
Leicester Diabetes Centre
Leicester, UK
Elaine Y.K. Chow
Department of Medicine and Therapeutics
Hong Kong Institute of Diabetes and Obesity
Li Ka Shing Institute of Health Sciences
Phase 1 Clinical Trial Centre
The Chinese University of Hong Kong
Prince of Wales Hospital
Hong Kong, SAR, China
Mikkel Christensen
University of Copenhagen
Copenhagen, Denmark
Emma J. Cockcroft
Faculty of Health & Life Science
Department of Health and Community Sciences
University of Exeter
Exeter, UK
Clive S. Cockram
The Chinese University of Hong Kong
Hong Kong SAR, China
Amanda J. Cox
Menzies Health Institute Queensland and School of
Pharmacy and Medical Sciences
Griffith University
Southport, QLD, Australia
Allan W. Cripps
Menzies Health Institute Queensland and School of
Medicine
Griffith University
Southport, QLD, Australia
Nicola Dalbeth
Department of Primary Care Health Sciences
University of Oxford
Oxford, UK
David A. D'Alessio
Department of Medicine, Division of
Endocrinology
Duke University
Durham, NC, USA
Sophia Dahm
Department of Diabetes, Central Clinical School
Monash University
Melbourne, Victoria, Australia
Christian Damgaard
Department of Odontology, Faculty of Health and
Medical Sciences
University of Copenhagen
Copenhagen, Denmark
Devra K. Dang
University of Connecticut School of Pharmacy
Storrs, CT, USA
Giuseppe Daniele
Department of Clinical and Experimental Medicine
University of Pisa
Pisa, Italy
Thomas Danne
Diabetes Center, Children's Hospital AUF DER
BULT
Hannover Medical School
Hannover, Germany
Stefano Del Prato
Department of Clinical and Experimental Medicine
University of Pisa
Pisa, Italy
Sonya Deschênes
School of Psychology
University College Dublin
Dublin, Ireland
Ketan Dhatariya
Norfolk and Norwich University Hospitals NHS
Foundation Trust
University of East Anglia
Norwich, UK
Trisha Dunning
Formerly of Deakin University
Geelong, Victoria, Australia
Sally Eastwood
Queen Elizabeth Centre, Ballarat Health
Service and
Department of Forensic Medicine, Monash
University
Melbourne, Australia
Emma English
Faculty of Medicine and Health
University of East Anglia
Department of Clinical Biochemistry
Norfolk and Norwich University Hospital Trust
Norwich, UK
Gian Paolo Fadini
Department of Medicine
University of Padova
Padova, Italy
Sadaf Farooqi
Wellcome-MRC Institute of Metabolic Science
Addenbrooke's Hospital
Cambridge, UK
Nick Finer
National Centre for Cardiovascular Prevention and
Outcomes
UCL Institute of Cardiovascular Science
London, UK
Allan Flyvbjerg
Steno Diabetes Center Copenhagen and
Department of Clinical Medicine, Faculty of Health
and Medical Sciences, University of Copenhagen
Copenhagen, Denmark
Keeley J. Foley
Department of Medicine, University of Manchester
Manchester Royal Infirmary
Manchester, UK
Miller School of Medicine
University of Miami
Miami, FL, USA
Hannah Forde
Leicester Diabetes Centre
Leicester, UK
Jackie Fosbury
Sussex Community NHS Foundation Trust
Brighton, UK
Kendra L. Francis
UW Medicine Diabetes Institute, Department of
Medicine
University of Washington
Seattle, WA, USA
Brian M. Frier
Centre for Cardiovascular Science, The Queen's
Medical Research Institute
University of Edinburgh
Edinburgh, UK
Emily J. Gallagher
Division of Endocrinology, Department
of Medicine
Icahn School of Medicine at Mount Sinai
New York, NY, USA
Andrew Grey
Department of Medicine
University of Auckland
Auckland, New Zealand
Nicola Guess
Department of Primary Care Health Sciences
University of Oxford
Oxford, UK
Ahmed Handhle
East Hertfordshire Hospitals Trust
Lister Hospital
Stevenage, UK
Department of Clinical Biochemistry
Addenbrooke's Hospital
Cambridge, UK
Wasim Hanif
University Hospitals Birmingham NHS...
