Transdermal Drug Delivery Systems
Revised and Expanded
2nd Edition
Published on 29. October 2002
328 pages
978-1-135-56519-0 (ISBN)
Description
Presents authoritative state-of-the-art discussions of the key issues pertinent to transdermal drug delivery, examining those topics necessary to enable a critical evaluation of a drug candidate's potential to be delivered across the skin; from physical chemistry and assessment of drug permeability to available enhancement technolgies, to regulator
More details
Edition
2nd edition
Language
English
Place of publication
London
United Kingdom
Publishing group
Taylor & Francis Ltd
Target group
Professional and scholarly
Edition type
Revised edition
Product notice
Reflowable
ISBN-13
978-1-135-56519-0 (9781135565190)
Copyright in bibliographic data and cover images is held by Nielsen Book Services Limited or by the publishers or by their respective licensors: all rights reserved.
Schweitzer Classification
Other editions
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Person
Jonathan Hadgraft
Content
Preface
Contributors
1. Feasibility Assessment in Topical and Transdennal Delivery:
Mathematical Models and In Vitro Studies
Jonathan Hadgraft and Richard H. Guy
iii
vii
2. Evaluating the Transdennal Permeability of Chemicals 25
Brent E. Vecchia and Annene L Bunge
3. Skin Absorption Databases and Predictive Equations 57
Brent E. Vecchia and Annene L Bunge
4. Partitioning of Chemicals into Skin: Results and Predictions 143
Brent E. Vecchia and Annene L Bunge
5. Iontophoresis: Applications in Drug Delivery and Noninvasive
Monitoring 199
M. Begona Delgado-Charro and Richard H. Guy
6. Skin Electroporation for Transdennal and Topical Drug
Delivery 227
Wronique Preat and Rita Vanbever
vi Contents
7. Sonophoresis: Ultrasound-Enhanced Transdennal Drug Delivery 255
Victor Meidan
8. Metabolic Approach to Transdennal Drug Delivery 285
Peter M. Elias, Kenneth R. Feingold, Janice Tsai,
Carl Thornfeldt, and Gopinathan Menon
9. The Application of Supersaturated Systems to Percutaneous
Drug Delivery 305
Mark Pellett, S. Lakshmi Raghavan, Jonathan Hadgraft, and
Adrian Davis
10. Minimally Invasive Systems for Transdennal Drug Delivery 327
James A. Down and Noel G. Harvey
11. Transdennal Drug Delivery System Regulatory Issues 361
Vinod P. Shah
Index
Contributors
1. Feasibility Assessment in Topical and Transdennal Delivery:
Mathematical Models and In Vitro Studies
Jonathan Hadgraft and Richard H. Guy
iii
vii
2. Evaluating the Transdennal Permeability of Chemicals 25
Brent E. Vecchia and Annene L Bunge
3. Skin Absorption Databases and Predictive Equations 57
Brent E. Vecchia and Annene L Bunge
4. Partitioning of Chemicals into Skin: Results and Predictions 143
Brent E. Vecchia and Annene L Bunge
5. Iontophoresis: Applications in Drug Delivery and Noninvasive
Monitoring 199
M. Begona Delgado-Charro and Richard H. Guy
6. Skin Electroporation for Transdennal and Topical Drug
Delivery 227
Wronique Preat and Rita Vanbever
vi Contents
7. Sonophoresis: Ultrasound-Enhanced Transdennal Drug Delivery 255
Victor Meidan
8. Metabolic Approach to Transdennal Drug Delivery 285
Peter M. Elias, Kenneth R. Feingold, Janice Tsai,
Carl Thornfeldt, and Gopinathan Menon
9. The Application of Supersaturated Systems to Percutaneous
Drug Delivery 305
Mark Pellett, S. Lakshmi Raghavan, Jonathan Hadgraft, and
Adrian Davis
10. Minimally Invasive Systems for Transdennal Drug Delivery 327
James A. Down and Noel G. Harvey
11. Transdennal Drug Delivery System Regulatory Issues 361
Vinod P. Shah
Index
