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Glycoconjugate Research, Volume II contains the proceedings of the Fourth International Symposium on Glycoconjugates held in Woods Hole, Massachusetts in 1977. The papers explore the biosynthesis and regulation of glycoconjugates, particularly those of cell membranes, and glycolipid storage diseases. This volume is comprised of 95 chapters divided into three sections. After reviewing the regulatory mechanisms underlying glycoprotein synthesis, it turns to enzymic modifications of sialic acids in the course of glycoconjugate biosynthesis. The following chapters focus on the biosynthesis and characterization of lipid-linked sugars in the outer membrane of liver mitochondria; effect of bacitracin on the biosynthesis of dolichol derivatives in calf pancreas microsomes; secretion of proteoglycans by chondrocytes; and heterogeneity of arterial proteoglycans. The biosynthesis of elastin by chondroblasts in monolayer cultures is also considered, along with the phosphorylation of proteoglycans in human articular cartilage. The final chapter describes a double-antibody radioimmunoassay for soluble and cell-surface blood group Ii antigens. This book will be a useful resource for biochemists.
Language
Place of publication
Publishing group
Elsevier Science & Techn.
ISBN-13
978-0-323-14532-9 (9780323145329)
Schweitzer Classification
Contents of VolumeBiosynthesis and Regulation The Control of Glycoprotein Synthesis Enzymic Modifications of Sialic Acids in the Course of Glycoconjugate Biosynthesis Role of Lipid-Saccharide Intermediates in Glycoprotein Biosynthesis Distinction and Partial Characterization of Two Galactosyltransferase Activities in Normal Human Serum Characterization of Two Highly Purified Fucosyltransferases Purification by Affinity Chromatography and Properties of Microsomal Galactosyltransferase from Pig Thyroid Sheep Brain Glycoprotein Fucosyltransferase The Incorporation of [14C]Glucosamine into Glycosaminoglycans and the Influence of Corneal Epithelium onThis Process Biosynthesis of Blood Group N- and M-Specific Haptenic Structures by Human Serum Glycosyltransferases Biosynthesis and Characterization of Lipid-Linked Sugars in Outer Membrane of Liver Mitochondria Incorporation of N-Acetylglucosamine and Mannose in Rat Liver Rough Microsomes: Stimulation by GTP after Treatment with Pyrophosphate Release of Complex Carbohydrates into Culture Medium by Cultured Hamster Cells On the Biosynthesis of Carboxypeptidase Y(CY) Metabolism of Free Sialic Acid, CMP-Sialic Acid, and Bound Sialic Acid in Rat Brain Effect of Bacitracin on the Biosynthesis of Dolichol Derivatives in Calf Pancreas Microsomes Biosynthesis of Dolichol Derivatives Containing D-Galactose in Calf Pancreas Microsomes Sulfogalactosyl Glycerides (SGG) from Rat Brain Myelin Complex Formation by Sequential Glycosyltransferases Biosynthesis of Heparin: Tritium Incorporation into Chemically Modified Heparin Catalyzed by C-5-Uronosylepimerase Serum Glycosyltransferase Enzymes in Normal and Leukemic Subjects: Experiences with Low-Molecular-Weight Acceptors Transfer of Glucose to Phenolic Steroids and Possible Physiological Role of the Glucosides Secretion of Proteoglycans by Chondrocytes.