
Cancer Systems and Control for Health Professionals
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First-of-its-kind resource exploring how cancer care fits into a general health system, contributed to by internationally eminent interdisciplinary experts
Cancer Systems and Control for Health Professionals delivers a comprehensive overview of the subject of cancer control, cancer services and systems organization and performance, principles of care delivery, cancer policy and social issues. Its distinguishing feature lies in its systematic exploration of cancer through a holistic lens, emphasizing systems-level understanding and the application of cancer control theory principles to address its complexities.
Through this holistic lens, readers are invited to appreciate the complex interactions of patients, caregivers, cancer biology, health policy, politics and health human resources. Readers will find strategies to reduce the incidence, morbidity, and mortality of cancer and to improve the quality of life through the implementation of prevention, early detection, diagnosis, treatment, and supportive and palliative care in a population.
Throughout the text, examples are given of how understanding different cancer control ecosystems can improve engagement in various parts of the world.
With contributions by global experts in the field with diverse backgrounds in education, technology, public health, health policy, and advocacy, Cancer Systems and Control for Health Professionals explore diverse topics including:
- Political and economic factors that frame cancer control
- The role of data management practices in advancing cancer control efforts and reducing inequality related to gender, race, and other demographic factors
- The transformative potential of emerging technologies such as artificial intelligence and quantum computing
- The complex interplay between social determinants of health, health economics, and cancer control strategies
- The urgency of addressing structural barriers to foster health equity and position cancer care within broader socio-political contexts
Cancer Systems and Control for Health Professionals is a timely, forward-thinking resource on the subject for oncologists, cancer professionals and researchers, public health professionals and researchers, and cancer control experts, along with students in related programs of study.
Meredith Giuliani is the Director of Education at Princess Margaret Cancer Centre and an Associate Professor in the Department of Radiation Oncology at the University of Toronto.
Mary Gospodarowicz is a Professor of Radiation Oncology at the University of Toronto.
James Brierley is a Professor of Radiation Oncology at the University of Toronto.
Richard Sullivan is a Professor of Cancer & Global Health and Director, Institute of Cancer Policy at King's College London.
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Content
Editor-in-Chief, Editors and Associate Editors vii
List of Section Editors ix
List of Contributors xi
Editors' bios xxi
Foreword xxiii
Preface xxv
1. Cancer Systems, Services and Policy 1
Introduction: Richard Sullivan
1.1 Politics of Cancer - Richard Sullivan and C.S. Pramesh 3
1.2 A Systems Approach to Cancer Care - Josep Maria Borras, Joan Prades and Josep Alfons Espinas 11
1.3 Therapeutic Geographies of Cancer in Conflict Settings - Mac Skelton and Omar Dewachi 19
1.4 Quality in Cancer Care - Megan McLeod and Ajay Aggarwal 25
2. The Political Economy of Cancer 35
Introduction: Beverley M. Essue and Richard Sullivan
2.1 Universal Health Coverage for Cancer - Adrian Gheorghe 37
2.2 Health Technology Assessment and Value- Based Care - Avram Denburg and Wanrudee Isaranuwatchai 43
2.3 Equity in Access to Cancer Care - Beverley M. Essue, Otuto Amarauche Chukwu and Ajay Aggarwal 51
2.4 Political Economy of Cancer in Turkey and Jordan - Tezer Kutluk, Omar Shamieh, Waleed Alrjoub, Asem Mansour and Richard Sullivan 61
3. Structure and Organisation of Cancer Services and System 69
Introduction: Meredith Giuliani
3.1 Cancer Centres: A Nexus for Modern Comprehensive Cancer Care and Control - Eleni Giannopoulos, Mary Gospodarowicz and C. S. Pramesh 71
3.2 Multidisciplinary and Interprofessional Care - Rana Jin, Maritza Carvalho, Alicia Martin, Andrew Dimech and Anet Julius 81
3.3 Palliative and Supportive Care - Jacqueline Alcalde, Arunangshu Ghoshal, Zipporah Ali, Felicia M. Knaul, Breffni Hannon and Camilla Zimmermann 89
3.4 Cancer Survivorship and Rehabilitation - Jiaoyang Cai, Melissa M. Hudson, Jennifer M. Jones and Nickhill Bhakta 97
3.5 Quality Improvement in Cancer Care: Principles and Application - Melanie Powis and Monika K. Krzyzanowska 109
4. Health Equity and Social Determinants of Cancer 119
Introduction: Beverley M. Essue and Ibrahim Abubakar
4.1 Social Determinants and Impacts of Cancer - Ibrahim Abubakar 121
4.2 Cancer and Indigenous Populations - Jason Gurney (Nga¯puhi), Jonathan Koea (Nga¯ti Mutunga, Nga¯ti Tama), Gail Garvey (Kamilaroi Nation) and Rodney Haring (Seneca Nation) 129
4.3 Women and Cancer - Beverley M. Essue, Ambreen Sayani, Aisha Lofters and Felicia M. Knaul 139
4.4 Cancer in Older Adults - Carolina Gómez- Moreno, Haydeé Verduzco- Aguirre and Enrique Soto- Perez- de- Celis 149
5. Data and Digitally Enabled Innovation in Cancer 155
Introduction: David Jaffray and Alejandro Berlin
5.1 The Expanding Demand for Data in Cancer Control - James Brierley, Brian O'Sullivan and Mary Gospodarowicz 157
5.2 Maximising and Enhancing the Value of Data in Oncology - Caroline Chung 163
5.3 Digitalisation and Cancer: Transforming, Securing and Informing Future Cancer Services - David Jaffray and Alejandro Berlin 171
5.4 Convergence of Digital Technologies for Cancer - Olivier Morin and David A. Jaffray 179
6. Education 187
Introduction: Meredith Giuliani
6.1 Health Literacy and Health- Literate Organisations - Janet Papadakos, Urska Kosir and Zodwa Dlamini 189
6.2 Communication for Cancer Control - David Wiljer and Gabrielle Kane 199
6.3 Health Human Resource Strategies - Nazik Hammad, Dario Trapani, Omar Abdihamid, Haimanot Kasahun Alemu and Verna Vanderpuye 205
6.4 Health Professions Education - Sandra Turner, Erica Liebermann, Daniel W. Golden, Aidan Leong, Miriam Mutebi and Jesper Grau Eriksen 215
7. Cancer Research 227
Introduction: Anna J. Dare and Danielle Rodin
7.1 Cancer Epidemiology, Risk Factors and Prevention Research - Valerie McCormack, Isabelle Soerjomataram, Michele Matta, Freddie Bray and Joachim Schüz 229
7.2 Cancer Genomics, Biomarkers and Precision Medicine - Leslie E. Oldfield and Trevor J. Pugh 243
7.3 Cancer Clinical Trials and Collaboratives - Matthew R. Sydes, Duncan C. Gilbert, Sharon B. Love and Angela M. Meade 253
7.4 Health Services and Outcomes Research for Cancer Control - Stephen Knight, Priya Ranganathan, Ewen M. Harrison and C.S. Pramesh 263
7.5 Achieving Seismic Change in Policy and Practice: A New Zealand Case Study - Christopher G.C.A. Jackson and Jason Gurney 269
Union for International Cancer Control (UICC) 277
Index 279
List of Contributors
Omar Abdihamid, MD, MMed, MPH
Garissa Regional Cancer Center
Garissa County Referral Hospital
Garissa, Kenya
Ibrahim Abubakar, PhD, FMedSci
University College London
London, UK
Ajay Aggarwal, MD, MRCP, FRCR, PhD
Faculty of Public Health and Policy
London School of Hygiene and Tropical Medicine
Guy's & St Thomas' NHS Trust
London, UK
Jacqueline Alcalde, MD, MMedSci
Department of Supportive Care
Princess Margaret Cancer Centre, University Health Network
Toronto, Canada
Division of Palliative Medicine, Department of Medicine
University of Toronto
Toronto, Canada
Haimanot Kasahun Alemu, MD
St. Paul's Hospital Millennium Medical College (HKA)
Addis Ababa, Ethiopia
Zipporah Ali, MD, MPH, MPC
Kenya Hospices and Palliative Care Association
Nairobi, Kenya
Waleed Alrjoub, BSc
King Hussein Cancer Center
Amman, Jordan
Alejandro Berlin, MD, MSc
Radiation Medicine Program, Princess Margaret Cancer Centre
University of Toronto
Toronto, Canada
Nickhill Bhakta, MD, MPH
Department of Global Pediatric Medicine
St. Jude Children's Research Hospital
Memphis, TN, USA
Josep Maria Borras, MD, PhD
Department of Clinical Sciences, IDIBELL
University of Barcelona
Catalan Cancer Plan, Department of Health
Barcelona, Spain
Freddie Bray, PhD
International Agency for Research on Cancer
Lyon, France
James Brierley, MBBS, FRCR, FRCP, FRCPC
Department of Radiation Oncology, Princess Margaret Cancer Centre
University of Toronto
Toronto, Canada
Jiaoyang Cai, MD, PhD
Department of Hematology/Oncology, Shanghai Children's Medical Center
Shanghai Jiao Tong University School of Medicine
National Children's Medical Center
Shanghai, China
Maritza Carvalho, RN, BN, MHSc, CON(C)
Princess Margaret Cancer Centre
University Health Network
Toronto, Canada
Otuto Amarauche Chukwu, MPharm, BPharm
Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health
University of Toronto
Toronto, Canada
Caroline Chung, MD, MSc, FRCPC, CIP
Divisions of Radiation Oncology and Diagnostic Imaging
UT MD Anderson Cancer Center
Houston, TX, USA
Anna J. Dare, MBChB, PhD, FRCSC
Department of Surgery
University of Toronto
Division of General Surgery
St. Michael's Hospital
Toronto, Canada
Avram Denburg, MD, MSc, PhD, FRCPC
Division of Haematology/Oncology
The Hospital for Sick Children
Institute for Health Policy, Management and Evaluation
University of Toronto
Toronto, Canada
Omar Dewachi, MD, PhD, MPH
Department of Anthropology
Rutgers University
New Brunswick, NJ, USA
Andrew Dimech, RN, BN, MSc ICU, Dip Onc.
Peter MacCallum Cancer Centre
University of Melbourne
Melbourne, Australia
Zodwa Dlamini, PhD
SAMRC Precision Oncology Research Unit (PORU), Pan African Cancer Research
Institute (PACRI)
University of Pretoria
Pretoria, South Africa
Jesper Grau Eriksen, MD, PhD
Department of Experimental Clinical Oncology
Aarhus University Hospital
Aarhus, Denmark
Josep Alfons Espinas, MD, PhD
Department of Clinical Sciences, IDIBELL
University of Barcelona
Catalan Cancer Plan, Department of Health
Barcelona, Spain
Beverley M. Essue, MPH, PhD
Institute of Health Policy, Management and Evaluation, Dalla Lana School of Public Health
University of Toronto
Toronto, Canada
Gail Garvey (Kamilaroi Nation), BEd, MEd, PhD
School of Public Health
University of Queensland
Brisbane, Australia
Adrian Gheorghe, PhD
Comprehensive Cancer Centre
King's College London
London, UK
Center for Global Development
Washington, DC, USA
Arunangshu Ghoshal, MD, MRes
Department of Supportive Care, Princess Margaret Cancer Centre
University Health Network, Toronto, Canada
Division of Palliative Medicine, Department of Medicine
University of Toronto
Toronto, Canada
Department of Palliative Medicine and Supportive Care
Kasturba Medical College and Hospital, Manipal Academy of Higher Education
Manipal, India
Eleni Giannopoulos, BSc, MMASc
Princess Margaret Cancer Centre
University Health Network
Toronto, Canada
Duncan C. Gilbert, MRCP, FRCR, PhD
MRC Clinical Trials Unit, Institute of Clinical Trials and Methodology
University College London
London, UK
Sussex Cancer Centre, Royal Sussex County Hospital
University Hospitals Sussex NHS Foundation Trust
Brighton, UK
Meredith Giuliani, MBBS, MEd, PhD, FRCPC, DRCPSC
Department of Radiation Oncology
University of Toronto
Princess Margaret Cancer Center
Toronto, Canada
Daniel W. Golden, MD, MHPE
Department of Radiation Oncology
Rush University Medical Center
Chicago, IL, USA
Carolina Gómez-Moreno, MD, MSc
Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán
Mexico City, Mexico
Mary Gospodarowicz, OC, MD, FRCPC, FRCR(Hon)
Department of Radiation Oncology
Princess Margaret Cancer Centre
University Health Network
Toronto, Canada
Jason Gurney (Ngapuhi), BSc(Hons), PhD
Department of Public Health
University of Otago
Wellington, New Zealand
Nazik Hammad, MD, FRCPC, MSc, MEHP, FACP
Division of Hematology-Oncology,
St Michael's Hospital
University of Toronto
Toronto, Canada
Breffni Hannon, MB BCh BAO, MMedSci
Department of Supportive Care, Princess Margaret Cancer Centre
University Health Network, Toronto, Canada
Division of Palliative Medicine, Department of Medicine
University of Toronto
Toronto, Canada
Rodney Haring (Seneca Nation), PhD, MSW
Roswell Park Comprehensive Cancer Center
New York, USA
Ewen M. Harrison, OBE, MB, ChB, MSc, PhD, FRCS, FRSE, FMedSci
Centre for Medical Informatics
Usher Institute
University of Edinburgh
Edinburgh, UK
Melissa M. Hudson, MD
Department of Oncology
St. Jude Children's Research Hospital
Memphis, TN, USA
Wanrudee Isaranuwatchai, PhD, BSc
Institute for Health Policy, Management and Evaluation
University of Toronto
Toronto, Canada
Health Intervention and Technology Assessment Program (HITAP)
Ministry of Public Health
Nonthaburi, Thailand
Christopher G.C.A. Jackson, MBChB, FRACP
Department of Medicine, Otago Medical School
University of Otago
Dunedin, New Zealand
David A. Jaffray, PhD
Departments of Radiation Physics and Imaging Physics
UT MD Anderson Cancer Center
Houston, TX, USA
Rana Jin, RN, DNP, CON(C)
Princess Margaret Cancer Centre
University Health Network
Toronto, Canada
Jennifer M. Jones, PhD
Department of Psychiatry, Dalla Lana School of Public Health
University of Toronto
Princess Margaret Cancer Centre
Toronto, Canada
Anet Julius, RN, BScN, MN, CON(C)
Princess Margaret Cancer Centre
University Health Network
Lawrence S. Bloomberg Faculty of Nursing
University of Toronto
Toronto Centre South Regional Cancer Program, Ontario Health
Toronto, Canada
Gabrielle Kane, MB, BCh, EdD, FRCPC, FSACME
Department of Radiation Oncology
University of Washington
Seattle, WA, USA
Felicia M. Knaul, PhD
Sylvester Comprehensive Cancer Center
Institute for Advanced Study of the Americas
Department of Public Health Sciences and Leonard M. Miller School of Medicine
University of Miami
Coral Gables, FL, USA
and
Tómatelo a Pecho AC
Mexico City, Mexico
and
Faculty of Excellence
Tecnológico de Monterrey
Monterrey, Mexico
Stephen Knight, MBChB (Hons), PhD, FRCS(Ed)
Center for Medical Informatics, Usher Institute
University of Edinburgh
Edinburgh, UK
School of Health and Wellbeing
University of Glasgow
Glasgow, UK
Jonathan Koea (Ngati Mutunga, Ngati Tama), MD, MHB (Hons), MBChB
Health NZ - Waitemata
University of Auckland
Auckland
New Zealand
Urska Kosir, DPhil (PhD)
Department of Experimental Psychology
University of Oxford
Oxford, UK
Monika K. Krzyzanowska, MD, MPH, FRCPC, FASCO
Cancer Quality Lab (CQuaL)
Division of Medical Oncology and Hematology
Princess Margaret Cancer Centre
Institute of Health Policy, Management and Evaluation
University of Toronto
Odette Cancer Centre, Sunnybrook Health Sciences Centre
Toronto, Canada
Tezer Kutluk, MD, PhD
Faculty of Medicine and Cancer Institute
Hacettepe University
Ankara, Turkey
Aidan Leong, MHealSc, BHealSc(Hons)
Department of Radiation Therapy
University of Otago
Bowen Icon Cancer Centre
Wellington, New Zealand
Erica Liebermann, PhD, ANP, WHNP
College of Nursing
University of Rhode Island
Providence, RI, USA
Aisha Lofters, MD, PhD
Department of Family & Community Medicine
University of...
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