
Electron Paramagnetic Resonance
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Content
- ELECTRON PARAMAGNETIC RESONANCE
- Contents
- Chapter 1 Biological Free Radicals
- 1 Introduction and Scope of Review
- 2 Metal Ions
- 2.1 Iron
- 2.2 Copper
- 2.3 Chromium
- 2.4 Other Metal Ions
- 3 Hydroperoxides
- 3.1 Alkyl/Aryl Hydroperoxides
- 3.2 Amino Acid, Protein and Nucleic Acid Hydroperoxides
- 4 Protein-derived Radicals
- 5 Veratyl Alcohol
- 6 Beta-amyloid Protein
- 7 Ozone
- 8 Nitric Oxide
- 9 Peroxynitrite(ONOO?)
- 10 Asbestos, Mineral Fibres and Diesel Particles
- 11 Cigarette Smoke
- 12 Paraquat
- 13 Halogenated Compounds
- 14 Ethanol
- 15 Retinoic Acid
- 16 Quinones
- 17 Phenols and Related Compounds
- 18 Thiols, Disulfides and Related Compounds
- 19 Ascorbate
- 19.1 Clinical Studies
- 19.2 Animal Studies
- 19.3 In Vitro Studies
- 20 Toxins
- 21 Hydroxylamines and Hydrazines
- 22 Diazonium and Tetrazolium Compounds
- 23 Nitro Compounds and Nitrogen Heterocycles
- 24 Photochemistry
- 24.1 UV-generated Radicals
- 24.2 Radical Generation from Exogenous Photosensitisers
- 24.3 Other Photochemical Studies
- 25 Ischemia-Reperfusion Injury
- 25.1 Heart and Vasculature
- 25.2 Brain
- 25.3 Liver, Kidney and Other Organs
- 26 Radiation Dosimetry
- 27 Spin Trap Artifacts and Misassignments
- References
- Chapter 2 Time-resolved Electron Paramagnetic Resonance Studies in Organic Photochemistry
- 1 Introduction
- 2 The Mechanisms of CIDEP
- 3 Theoretical Developments
- 4 TREPR Experiments
- 4.1 The TR (CW) EPR Experiment
- 4.2 TREPR at Multiple Microwave Frequencies
- 4.3 Optically Detected Magnetic Resonance (ODMR)
- 4.3.1 RYDMR
- 4.3.2 FDMR
- 4.3.3 ADMR
- 4.4 Quantum Beats
- 4.5 Fourier Transform EPR
- 5 Applications in Organic Photochemistry
- 5.1 Fullerenes
- 5.2 Photosynthetic Model Systems
- 5.3 Radical Pairs in Micelles
- References
- Chapter 3 Radiation Damage to DNA and Related Biomolecules
- 1 Introduction
- 1.1 Scope of this Report
- 1.2 Significance of the Field of Research
- 1.3 Symbols Used
- 2 DNA Constituents
- 2.1 Introduction
- 2.2 Pyrimidines
- 2.2.1 Single Crystal Studies
- 2.2.2 Frozen Aqueous Solutions and Glasses
- 2.3 Purines
- 2.3.1 Single Crystals
- 2.3.2 Glasses
- 2.4 Mixed Crystal Systems
- 2.5 Multi-base Investigations
- 2.5.1 Frozen Aqueous Solutions and Glasses
- 2.5.2 Peroxyl and Sulfoxyl Radicals
- 3 DNA, Polynucleotides and Oligonucleotides
- 3.1 Introduction
- 3.1.1 Symbols for DNA Radicals
- 3.1.2 The Direct, Quasi-direct and Indirect Effects
- 3.2 Radical Yields in DNA
- 3.2.1 Radical Distributions at Low Temperatures
- 3.2.2 Deconvolution of Complex Spectra: Important Confirmatory Results
- 3.2.3 Where are the Sugar Radicals in Irradiated DNA?
- 3.2.4 Evidence for Sugar Radicals in High LET Irradiated DNA
- 3.2.5 Recombination: An Important Fundamental Process in Radiation Damage to DNA
- 3.3 Radical Transfer in DNA
- 3.3.1 Electron Transfer Distances in DNA
- 3.3.2 Hole Transfer from the DNA Hydration Layer: Yields of Hydroxyl Radicals
- 3.4 DNA-Thiol Systems
- 3.5 Irreversible Protonation of Electron-gain Centers in DNA
- 3.6 Radiation Damage to DNA by Heavy-ion Beams
- 3.7 Spin Trapping of DNA Intermediates
- 3.8 New Techniques
- References
- Chapter 4 Spin-trapping: Recent Developments and Applications
- 1 Introduction
- 2 New Spin-traps
- 2.1 New Nitrones
- 2.2 New Isotopically-labelled Spin-traps
- 3 Applications in Organic Solvents
- 3.1 Spontaneous Formation of Spin Adducts
- 3.1.1 Inverted Spin-trapping
- 3.1.2 Other Mechanisms
- 3.2 Spin-trapping of Various Radicals
- 3.3 Miscellaneous
- 4 Applications in Aqueous Solutions
- 4.1 Superoxide
- 4.2 Hydroxyl Radical
- 5 Trapping of Nitric Oxide
- 6 Miscellaneous
- References
- Chapter 5 EPR and ENDOR Studies of Metalloproteins
- 1 Introduction
- 2 Copper
- 2.1 'Blue'Copper Sites
- 2.2 Type 2 Copper Sites
- 2.3 Binuclear Sites and Multi-centered Copper Proteins
- 3 Iron
- 3.1 Non-heme Iron Proteins
- 3.2 Heme-Iron Proteins
- 3.3 Iron-Sulfur Proteins
- 4 Nickel
- 5 Molybdenum and Tungsten
- 6 Vanadium
- 7 Manganese
- 8 Conclusions
- Acknowledgements
- References
- Chapter 6 Pulsed ESR of Microporous and Mesoporous Oxide Materials
- 1 Introduction
- 2 Organic Radicals
- 3 Transition Metal Ions
- 3.1 Cu(II) Systems
- 3.2 Ni(I) Systems
- 3.3 Pd(I) Systems
- 3.4 Fe(III) Systems
- 3.5 Mn(II) Systems
- 3.6 Ti(III) Systems
- 3.7 Cr(V), Mo(V) and V(IV) Systems
- 3.8 Paramagnetic Silver Clusters
- Acknowledgement
- References
- Chapter 7 Advanced EPR in Millimetre Bands and Very High Fields
- 1 Introduction
- 2 Techniques
- 3 Applications
- 3.1 Molecular Structure Studies
- 3.1.1 Single-electron Spin Systems
- 3.1.2 Multi-electron Spin Systems
- 3.2 Molecular Mobility Studies
- 4 High-field Low-temperature Effects
- 5 Conclusions
- Acknowledgments
- References
- Chapter 8 Electron Transfer Kinetics Studied by EPR/ESR and Related Methods
- 1 Introduction
- 2 Bibliography
- 3 Marcus Theory of Electron Transfer Reactions in Solution
- 4 Intermolecular Electron Transfer Rate Constants from EPR Measurements
- 4.1 Time-resolved EPR at Constant Magnetic Field
- 4.2 Dynamic ESR Line-broadening Measurements
- 4.2.1 Homogeneous Electron Self-exchange Reactions
- 4.2.2 Degenerate Intramolecular Electron Exchange Reactions
- 4.3 Electron Self-exchange Rates from Other Magnetic Resonance Methods
- 4.3.1 Fluorescence-detected Magnetic Resonance Measurements
- 4.3.2 Time-resolved CIDNP and CIDEP Measurements
- 4.3.3 FT-EPR Measurements
- 4.3.4 RYDMR and MARY Methods
- Acknowledgements
- References
- Author Index
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