Repetitive DNA
1st Edition
Published on 27. June 2012
230 pages
978-3-318-02150-9 (ISBN)
Available for download
Description
The experimental data that have been generated using new molecular techniques associated with the completion of genome projects have changed our perception of the structural features, functional implications and evolutionary dynamics of repetitive DNA sequences. This volume of Genome Dynamics provides a valuable update on recent developments in research into multigene families, centromeres, telomeres, microsatellite DNA, satellite DNA, and transposable elements. Each chapter presents a review by distinguished experts and analyzes repetitive DNA diversity and abundance, as well as the impact on genome structure, function and evolution. This publication is targeted at scientists and scholars at every level, from students to faculty members, and, indeed, anyone involved or interested in genetics, molecular evolution, molecular biology as well as genomics will find it a valuable source of up-to-date information.
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Garrido-Ramos
Repetitive DNA
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06/2012
1st Edition
S. Karger
€279.25
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Content
- Cover
- Contents
- Editorial
- References
- Preface
- The Repetitive DNA Content of Eukaryotic Genomes
- Abstract
- The Repetitive Fraction of Eukaryotic Genomes
- Gene Families
- Microsatellite DNA
- Minisatellite DNA
- Satellite DNA
- Centromeres and Telomeres
- Transposable Elements
- Segmental Duplications
- Acknowledgements
- References
- Telomere Dynamics in Mammals
- Abstract
- Telomere Structure
- Maintaining Telomere Lengths: the End Replication Problem
- Telomere Length Homeostasis: the Long and the Short of It
- Shelterin and Telomere Dynamics
- Telomeric Chromatin
- Transcription at Telomeres: TERRA
- An Enlarged View of Telomeres: the Telosome
- Telomeres and Chromosome Instability and Their Role in Cancer
- Lengthening Telomeres without Telomerase: Alternative Lengthening of Telomeres
- Telomeres, Aging and Lifespan
- Telomere Dynamics beyond Telomeres
- Acknowledgements
- References
- Drosophila Telomeres: an Example of Co-Evolution with Transposable Elements
- Abstract
- The Telomeric Retrotransposons: HeT-A, TART and TAHRE
- Telomere Elongation in Drosophila
- Telomere Protection in Drosophila
- Telomere Domains in Drosophila
- Evolution of Telomeres
- Conclusions
- References
- The Evolutionary Dynamics of Transposable Elements in Eukaryote Genomes
- Abstract
- Classification and Mechanisms of Transposition
- Mode of Transmission of Transposable Elements
- Abundance and Diversity of Transposable Elements in Eukaryotes
- The Impact of Natural Selection on Transposable Elements
- The Impact of Host Demography and Life History on Transposable Elements
- Post-Insertional Control of Transposon Copy Number
- Conclusion
- References
- SINEs as Driving Forces in Genome Evolution
- Abstract
- SINEs Substantially Expand the Genomic Space
- SINEs Introduce Structural Variants of the Genome
- SINEs Influence or Regulate Gene Expression
- SINEs Evolve into Protein-Coding Sequences
- Summary
- Acknowledgements
- References
- Unstable Microsatellite Repeats Facilitate Rapid Evolution of Coding and Regulatory Sequences
- Abstract
- Repeats, Repeats, Repeats
- Tandem Repeats in Gene Coding Regions
- Tandem Repeats in Regulatory Sequences
- Conclusions
- Acknowledgements
- References
- Satellite DNA Evolution
- Abstract
- Satellite DNA Sequence Features
- Concerted Evolution
- Dynamics of Satellite DNA Evolution
- Satellite DNA Library Concept
- Satellite DNA Evolution and Centromere
- Evolution of Alpha Satellite Repeats
- References
- Satellite DNA-Mediated Effects on Genome Regulation
- Abstract
- Functional Constraints on Satellite DNA Sequence
- Transcription of Satellite DNAs
- Satellite RNAs as Epigenetic Regulators of Heterochromatin Establishment
- Satellite RNA as Structural Component of Centromeres
- Satellite DNAs as cis-Regulatory Elements of Gene Expression
- Heterochromatin and Satellite DNA Response to Environmental Stimuli
- Acknowledgements
- References
- The Birth-and-Death Evolution of MultigeneFamilies Revisited
- Abstract
- Rates of Birth-and-Death Evolution: Lessons from Gene Families of the Chemosensory System
- Birth-and-Death Evolution and Genomic Drift: Evolving Evolutionary Novelty in the Fatty Acid Reductase Multigene Family
- Birth-and-Death Evolution and Selective Constraints: Histone Variant Diversification in the Germinal Cell Line
- Mixed Effects of Birth-and-Death and Concerted Evolution: the 5S rDNA Gene Family in Fishes and Molluscs
- Concluding Remarks
- Acknowledgements
- References
- Chromosomal Distribution and Evolution of Repetitive DNAs in Fish
- Abstract
- The Repetitive Fraction of the Genome
- Fish Genomes and Their Impact on Evolutionary Studies
- Repeated DNAs in Fish Genomes: A Chromosomal Perspective
- The Repetitive DNA Fraction: A Primary Driving Force behind the Diversity of Fish
- Structure and Evolution of Fish Sex Chromosomes
- Origin and Maintenance of B Chromosomes
- Future Perspectives: Cytogenomics
- Acknowledgements
- References
- Author Index
- Abbreviations
- Latin Species Names
- Subject Index
- Cover
