
Biomedical Engineering Systems and Technologies
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Content
- Intro
- Title
- Preface
- Organization
- Table of Contents
- Invited Papers
- Personal Health:The New Paradigm to Make Sustainable the Health Care System
- Introduction
- Telemedicine and Health
- New Paradigm for Health Care Systems
- Disruptive Innovation
- Chronic Disease Challenge
- Personal Health Systems
- Information and Communication Technologies (ICT)
- RFID
- Sensors
- Internet 2.0
- Electronic Health Records
- Ambient Intelligence
- Conclusions
- References
- Part I Health Informatics
- Registration and Fusion Techniques for Medical Images: Demonstration and Evaluation
- Introduction
- System Architecture
- Data Collection and Data Management Subsystem
- Medical Data Preprocessing Subsystem
- Medical Data Alignment Subsystem
- Medical Data Fusion Subsystem
- Graphical Interface Subsystem
- Working Environment
- Pilot Scenario
- Quantitative Analysis of Registration Results
- Three-Dimensional Display of Anatomic Structures
- Conclusions
- References
- Prediction of Pancreatic Cancer Survival through Automated Selection of Predictive Models
- Introduction
- Machine Learning
- Classical Meta-learning
- Proposed Automated Model Selection Meta-learning Approach
- Plan of the Paper
- Pancreatic Cancer Clinical Datasets
- Pre-operative and All-attributes Predictive Attribute Sets
- Prediction Target Attribute
- Summary of Datasets Considered
- Learning to Predict the Best Performing Model
- Model Selection Meta-learning for Prediction
- Training the Model Selection Metalearner
- Evaluation
- Preprocessing and Predictive Techniques Used
- Experimental Protocol
- Results and Discussion
- Conclusions
- References
- Web of Active Documents: An Architecture for Flexible Electronic Patient Records
- Motivations and Background
- Webs of Active Documents
- Datoms, Didgets and Templates
- Mechanisms in the WOAD Framework
- Interaction with the WOAD Architecture
- Conclusions and Future Work
- References
- A Personalization Environment for Multi-version Clinical Guidelines
- Introduction
- Versioning of Clinical Guidelines
- Temporal Versioning
- Semantic Versioning
- An XML Data Model for Multi-version Guidelines
- Manipulation and Retrieval Operations
- Prototype Implementation
- Conclusions and Future Work
- References
- Dynamic Routing Using Health Information Policy with Apache Camel
- Introduction
- Background
- Message-Oriented Middleware (MOM)
- Enterprise Integration Patterns
- Apache Camel
- Health Information Policy
- Implementing Information Policy
- Routing Based on Medical Context
- Enriching Messages with Medical Context
- Test Scenario
- Conclusions
- References
- A Personal Health Record System for Emergency Case Management
- Introduction
- Related Work
- Motivating Scenario
- System Architecture
- Security Architecture
- Access Control Policies
- Context Information Management
- Implementation Issues
- Concluding Remarks
- References
- A Method for Representing and Querying Temporal Information in OWL
- Introduction
- Background
- Temporal Model
- Temporal Querying
- Basic Temporal Queries: Allen's Operators
- More Advanced Temporal Queries: Grouping and Aggregation
- More Advanced Temporal Queries: Temporal Collections
- Conclusions
- References
- Designing a Telemedical System for Cardiac Exercise Rehabilitation
- Introduction
- Rehabilitation after Cardiac Events
- User Centered Design of Telemedicine Applications
- Technical Requirements of Telemedicine Applications
- Related Work
- Background: OSAmI-D
- A User Study
- Interview Lead through
- The Current Setting
- Results
- User Interface Design
- Mockups
- Conclusions
- References
- A Value and Model Driven Method for Patient Oriented KPI Design in Health Care
- Introduction
- Related Work
- Method for Value Based KPI Identification
- Task 1: Develop Value Model
- Task 2: Generate Technical KPIs
- Task 3: Generate Functional KPIs
- Method Application
- Concluding Remarks
- References
- Part II Biomedical Electronics and Devices
- Encapsulated Multi-vesicle Assemblies of Programmable Architecture: Towards Personalized Healthcare
- Introduction
- Material and Methods
- Results
- Discussion
- Encapsulation
- Compartmentalization
- Composition Control
- Conclusions
- References
- Adaptive RBF-HMM Bi-Stage Classifier Applied to Brain Computer Interface
- Introduction
- Experimental Procedure
- Flow of Activities in the Experimental Process
- Electrode Position
- Description of Cognitive Activities
- Description of the Classifier
- Introduction
- Preprocessing
- Training of the Neural Network
- Description of Hidden Markov Models
- Training of the Hidden Markov Models
- Results
- Evaluation of the Learning Capability
- Evaluation of the Generalisation Capability
- Discussion
- Conclusions
- References
- Thermal Characteristics of Microcantilever Biosensors
- Introduction
- Theory and Numerical Analysis
- Numerical Analysis
- Results and Discussion
- Conclusions
- References
- Prosodic Speech Restoration Device: Glottal Excitation Restoration Using a Multi-resolution Approach
- Introduction
- Speech Rehabilitation for Alaryngeal Speakers
- Characteristics of Pathological Speech
- Multi-resolution Voice Restoration
- Method
- Long-Term Pitch Estimation
- Middle-Term Pitch Restoration
- Short-Term Pitch Restoration
- Results
- Conclusions
- References
- An Investigation on ALD Thin Film Evanescent Waveguide Sensor for Biomedical Application
- Introduction
- Fabrication
- Buckling of Thin Film
- Front Side Fabrication
- Propagation Losses
- Free Standing Structure
- Free Standing Processing
- New Structure Definition
- Conclusions
- References
- Part III Bio-inspired Systems and Signal Processing
- Probabilistic Patient Monitoring with Multivariate, Multimodal Extreme Value Theory
- Introduction
- Existing Patient Monitors
- Intelligent Patient Monitoring
- Contributions in This Paper
- Classical Extreme Value Theory
- Redefining ``Extrema''
- Density Estimation
- Method
- Introduction
- Detail of Method
- Novelty Score Assignment
- Validation on Simulated Data
- Application to Vital-sign Data
- Discussion
- Conclusions
- Future Work
- Downloadable Content
- References
- Weighted SVMs and Feature Relevance Assessment in Supervised Heart Beat Classification
- Introduction
- State of the Art
- Theoretical Background
- Weighted SVM Classifier
- Hermite Basis Functions
- Higher Order Statistics
- ECG Database and Preprocessing
- Feature Extraction
- Experiments and Results
- Feature Relevance Assessment
- Peformance Evaluation
- Conclusions
- References
- The Investigation and Clinical Significance of Resonance in the Heart Rate and Vascular Tone Baroreflexes
- Introduction
- 0.1 Hz Resonance in the CVS
- Prior Studies: 0.1 Hz Resonance in the CVS Caused by Respiration
- Study 1: 0.1 Hz Resonance in the CVS Caused by Rhythmical Muscle Tension
- Study 2: 0.1 Hz Resonance in the CVS Caused by Emotional Pictures Cues
- 0.03 Hz Resonance in the CVS
- Study 1: 0.03 Hz Resonance in the CVS Caused by Aversive Sound
- Study 2: 0.03 Hz Resonance in the CVS Caused by Negative Emotional Pictures
- Discussion
- Conclusions
- References
- Glottal Inverse Filtering of Speech Based on Homomorphic Prediction: A Cepstrum-Based Algorithm Not Requiring Prior Detection of Either Pitch or Glottal Closure
- Introduction
- Simulated Voice Signals
- Simulation Model
- Characteristics of Simulated Glottal Signals
- Inverse Filtering Algorithms
- Iterative Adaptive Inverse Filtering (IAIF)
- Homomorphic Prediction (HoP)
- Results
- Conclusions
- References
- Texture Discrimination with Artificial Whiskers in the Robot-Rat Psikharpax
- Introduction
- System Description
- Texture Discrimination
- Feature Extraction
- Fixed Head Experiment
- Mobile Robot Experimentation
- Discussion
- Conclusions
- References
- Heart Rate Variability and the Acceleration Plethysmogram Signals Measured at Rest
- Introduction
- Data
- Methodology
- Detection of a-Waves
- HRV Analysis
- Results
- Conclusions
- References
- Emotional Face Perception in Healthy Subjects and Parkinson's Disease: An Effective Connectivity Study
- Introduction
- Methods
- Effective Connectivity Analysis
- Results
- Discussion
- Conclusions
- References
- Biometric Authentication with Electroencephalograms: Evaluation of Its Suitability Using Visual Evoked Potentials
- Introduction
- Electroencephalograms
- Visual Evoked Potentials (VEPs)
- Related Work
- An EEG-Based Authentication System Using VEP
- Personal Classifiers
- Authentication Process
- Description of the Data Set
- Feature Array Extraction
- The Feature Classifier
- Experimentation
- Overall Evaluation Results
- Evaluation of Individual Classifiers
- Open Issue: Constancy
- Conclusions
- References
- Part IV Bioinformatics
- Reconstructing the Phylogenetic Relationships of the Cyclophyllidean Cestodes: A Case Study Using ITS2 rDNA and Sequence-Structure Alignment
- Introduction
- Materials and Methods
- Sequence Alignments and Molecular Phylogenetic Analysis
- Bayeasian Phylogenetic Analysis
- ITS2 Secondary Structure Prediction and Sequence Structure Alignment Footnotes
- Results
- Neighbour-Joining (NJ) and Maximum Parsimony (MP) Trees
- Bayesian Phylogeny
- Secondary Structure Analysis and GC Content
- Discussion
- Conclusions
- References
- ReHap: A Framework for Single Individual Haplotyping from Next-Generation Sequencing Data
- Introduction
- Functionalities
- Algorithms Supported
- Algorithms Evaluation
- Experiments
- Conclusions
- References
- Inference of Large Phylogenies Using Neighbour-Joining
- Introduction
- Methods
- The Neighbour-Joining Method
- RapidNJ
- Reducing the Memory Consumption of RapidNJ
- An I/O Algorithm for Building Very Large Trees
- Improving the Search Heuristic
- Experiments
- Experimental Setup
- Results and Discussion
- Conclusions
- References
- Prediction of Minimum Free Energy Structure for Simple Non-standard Pseudoknot
- Introduction
- Simple Non-standard Pseudoknots
- Problem Definition
- Prediction Algorithm
- Subregion in Simple Non-standard Pseudoknot
- Dynamic Programming Algorithm
- Conclusions
- References
- Intra- and Inter-Molecular Coevolution: The Case of HIV1 Protease and Reverse Transcriptase
- Introduction
- Materials and Methods
- Sequence Data
- Information Theoretical Measures on (Co-)evolution
- Results
- Comparing Intra- and Inter-Protein Co-evolution of Residues
- Co-evolution between Residues in the PR and the RT?
- Discussion and Summary
- References
- Structured Output Prediction of Novel Enzyme Function with Reaction Kernels
- Introduction
- Enzyme Function Prediction
- Annotation Transfer Approaches
- Machine Learning Approaches
- Structured Output Learning
- Joint Kernels
- Learning Task
- Preimage Problem
- Kernels for Chemical Reactions
- Kernels for Molecule Graphs
- Sum-of-Reactants Kernel
- Reactant-Matching Kernels
- Experiments
- Data
- Compared Methods
- Measure of Success
- Results
- Discussion and Future Work
- References
- A Parallel Algorithm for Counting Subgraphs in Complex Networks
- Introduction
- Preliminaries
- Network Terminology
- Subgraph Census
- Related Work
- Parallel Algorithms
- Core Sequential Unit
- Initial Parallel Approaches
- Adaptive Parallel Enumeration
- Results
- Conclusions
- References
- Efficient Searching for Motifs in DNA Sequences Using Position Weight Matrices
- Introduction
- Position Weight Matrices
- Algorithm
- Algorithm Performance
- Space Performance
- Time Performance
- Discussion
- References
- Author Index
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