Theoretical Drug Design Methods
1st Edition
Published on 31. December 1984
415 pages
978-3-11-270699-2 (ISBN)
Description
No detailed description available for "Theoretical Drug Design Methods".
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Edition
rev., ext. English transl. of ,,Optimierungsmethoden in der Wirkstofforschung. Quantitative Struktur-Wirkungs-Analyse", publ. 1980 as ,,Sonderband 2" in the series ,,Beitrage zur Forschungstechnologie"., Reprint 2024
Language
English
Place of publication
Berlin/Boston
Germany
Target group
Professional and scholarly
US School Grade: College Graduate Student
Illustrations
With 44 Figures and 88 Tables
With 44 Figures and 88 Tables
File size
116,83 MB
ISBN-13
978-3-11-270699-2 (9783112706992)
Schweitzer Classification
Other editions
Additional editions
Rainer Franke
Theoretical Drug Design Methods
Book
12/1984
1st Edition
De Gruyter
€139.95
Shipment within 7-9 days
Content
- Intro
- Contents
- 1. Introduction and Formulation of Problems
- 2. Measures of Biological Activity A
- 3. Extrathermodynamic Approach to Quantitative Structure-Activity Analysis (Hansch Analysis)
- 4. Hydrophobic Effects on Biological Activity: the Function f⊂&n&/sub&(x⊂&h&/sub&)
- 5. Electronic Influences on Biological Activity: the Function f⊂&n&/sub&(x⊂&h&/sub&)
- 6. Steric Effects on Biological Activity: the Function f⊂&n&/sub&(x⊂&h&/sub&)
- 7. Interrelations of Molecular Parameters and the Collinearity Problem
- 8. Practical Aspects of Quantitative Structure-Activity Analysis by the Extrathermodynamic Approach (Hansch Analysis)
- 9. Other Approaches to Quantitative Structure-Activity Analysis with Extrathermodynamic Molecular Parameters
- 10. Non-Computer-Assisted Search Operations on the Basis of the Extrathermodynamic Approach
- 11. Procedures with Structural Parameters
- 12. Receptor Mapping and Pharmacophores
- 13. Response Profiles
- 14. Concluding Remarks
- 15. Appendix: Some Principles of Linear Regression Analysis
- 16. Index
