Structure and Function of Sarcoplasmic Reticulum
Published on 1. January 2013
636 pages
978-1-4832-7744-8 (ISBN)
Description
Structure and Function of Sarcoplasmic Reticulum is a compendium of papers from an International Conference on Sarcoplasmic Reticulum held in Japan on November 1-4, 1982. Section I is a review of sarcoplasmic reticulum including the "discovery" of the relaxing factor, the calcium binding of relaxing factor, as well as phosphate transfer and calcium transport coupling. Section II involves the chemistry and structure of the calcium pump protein in sarcoplasmic reticulum. One paper describes the role of protein-lipid interactions in the organization and function of biomembranes. Section III considers the kinetics and thermodynamics of the calcium pumping mechanism, particularly the binding of ligands to calcium ATPase of the sarcoplasmic reticulum, as well as the conformational changes of the sarcoplasmic reticulum Ca-ATPase induced by substrate binding and phosphorylation. A paper gives the results of several experimental techniques in substrates binding assays employing millipore filters and a thermostated filtration apparatus. Section IV describes the calcium ions release process such as rapid and reversible actions, while Section V discusses the regulation of calcium ions uptake and release in the ion channel vesicles. This book can be helpful for researchers in biophysical engineering, pharmacologists, and scientists in the fields of biochemistry and biophysics.
More details
Other editions
Additional editions
Sidney Fleischer | Yuji Tonomura
Structure and Function of Sarcoplasmic Reticulum
Book
01/1985
Academic Press
€53.86
Article exhausted; check different version
Content
ContributorsPrefaceYuji Tonomura (1923-1982)Section I Historical Background and Overview Relaxing Factor, Sarcoplasmic Reticulum, and Troponin - A Historical Survey The Sarcoplasmic Reticulum Calcium Pump: Early and Recent Developments Critically OverviewedSection II Chemistry and Ultrastructure of the Calcium Pump Protein in Sacroplasmic Reticulum Static and Time-Resolved Structural Studies of the Ca2 + -ATPase of Isolated Sarcoplasmic Reticulum Conformational Changes of Ca2+,Mg2+-Adenosinetriphosphatase as Detected by Site-Specifically Introduced Fluorescent andParamagnetic Probes and by Susceptibility to Tryptic Digestion Structural Analysis of the Ca2+,Mg2+-ATPase of Sarcoplasmic Reticulum Protein-Lipid Interaction in Sarcoplasmic Reticulum and Phospholipid-Replaced Membranes Sarcoplasmic Reticulum and Other Membranes in the Regulation of Skeletal Muscle Contraction and Relaxation: A Multilevel Approach A New Procedure for the Reconstitution of Sarcoplasmic Reticulum Vesicles by Salting-Out Method Target Size of Calcium Pump Protein from Skeletal Muscle Sarcoplasmic Reticulum Oligomeric Form of the Ca2+,Mg2+-Dependent ATPase in Sarcoplasmic ReticulumSection III Kinetics and Thermodynamics of the Calcium Pumping Mechanism A. Thermodynamic and Kinetic Considerations Binding of Ligands to Calcium ATPase of the Sarcoplasmic Reticulum Equilibrium and Kinetic Correlations of the Partial Reactions of the Ca2 + Transport Cycle Kinetic and Thermodynamic Aspects of ATP-Dependent Ca2+ Transport in Sarcoplasmic Reticulum Using ATPßS Diastereomers as Substrates Conformational Changes of the Sarcoplasmic Reticulum Ca-ATPase Induced by Substrate Binding and Phosphorylation Conformational Change of SR-ATPase Induced by Phosphorylation Mechanism for the Interconversion of Chemical and Osmotic Free Energy B. Kinetic Studies of the Calcium Pumping Cycle Kinetics of Accumulation of the ADP-Sensitive and ADP-Insensitive Phosphoenzymes and Their Relationship to Ca2+ Translocation in Sarcoplasmic Reticulum Pre-Steady State Kinetics of E~P Formation and Decomposition by Ca2+,Mg2 + -ATPase in Bovine Aorta Microsomes Theoretical Basis for the Sequence Analysis of the Reaction Steps Involved in the Transphosphorylation Process of the Sarcoplasmic Ca + +-Transport ATPase Ca2 + -Ca2 + Exchange Mediated by the Membrane-Bound Ca2+,Mg2+-ATPase of Sarcoplasmic Reticulum Vesicles Reaction Mechanism of ATP Hydrolysis by Sarcoplasmic Reticulum with CaATP as a Substrate Mechanism of ATP Synthesis in Sarcoplasmic Reticulum The Ca-ATPase of Sarcoplasmic Reticulum Catalyses a Monovalent Cation (Na,K) ExchangeSection IV The Ca2+ Release Process Rapid and Reversible Calcium Release from Sarcoplasmic Reticulum In Vitro Mechanism of Calcium Release from Sarcoplasmic Reticulum: Effect of Caffeine on Magnesium Binding to Fragmented Sarcoplasmic Reticulum from Bullfrog Skeletal Muscle Ca Releasing Action of Quercetin on the Sarcoplasmic Reticulum of Frog Skeletal Muscle The Effects of Adenine Nucleotide and External Ca2+ on Ca2+ Release from Fragmented Sarcoplasmic Reticulum in the Presence of Mg2 Calcium-Induced Calcium Release from Fragmented Sarcoplasmic Reticulum Calcium Impulse Appraisal of the Hypothesis of the "Depolarization-Induced" Release of Calcium from the Sarcoplasmic Reticulum in Skinned Cardiac Cells from the Rat or Pigeon Ventricle The Calcium-Induced Calcium Release from the Sarcoplasmic ReticulumSection V Regulation of Ca2+ Uptake and Release Ion Channels of Sarcoplasmic Reticulum Vesicles and Calcium Release Regulation of Ca2+ Pumping in Heart Sarcoplasmic Reticulum Resolution of the Regulatory Systems of the Cardiac Sarcoplasmic Reticulum Ca2+,Mg2+ -ATPase Index
