The Structure and Function of Chromatin
Published on 16. September 2009
352 pages
978-0-470-71778-3 (ISBN)
Description
The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world.
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05/2008
Wiley
€82.75
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Persons
David W. FitzSimons is the editor of The Structure and Function of Chromatin, published by Wiley.
Sir Gordon Ethelbert Ward Wolstenholme OBE FRCP was a British medical doctor, and the founding director of the Ciba Foundation. He was born in Sheffield, the son of a mechanical engineer, and educated at Repton School and Corpus Christi, Cambridge.
Content
- Intro
- The Structure and Function of Chromatin
- Contents
- Foreword: histone nomenclature
- Editors' note
- Introduction
- Chromosomal structure as seen by electron microscopy
- Discussion
- The specific template activity of chromatin
- Discussion
- Histone function and evolution as viewed by sequence studies
- Discussion
- Structure of histone H2A (histone ALK, IIbl or F2a2)
- Discussion
- Chromosomal proteins related to histones
- Discussion
- Chemistry of the non-histone chromosomal proteins
- Discussion
- Histones in chromosomal structure and control of cell division
- Discussion
- X-ray diffraction of nucleohistones from spermatozoa
- Discussion
- The regulatory role of non-histone proteins in RNA synthesis
- Discussion
- Sequence-specific binding of DNA by non-histone proteins and their migration from cytoplasm to nucleus during gene activation
- Discussion
- The biological roles of post-synthetic modification of basic nuclear proteins
- Discussion
- Micromodification of histone during the cell cycle
- Discussion
- Changes in chromatin structure and function in W138 cells stimulated to proliferate
- Discussion
- Some properties of the zones binding polylysine in chromatin
- The arrangement of histone complexes along the chromosomal fibre
- Discussion
- Regulation of gene expression in higher organisms: how it all works
- Discussion
- General Discussion
- Location of chromatin components
- Interaction sites for proteins in DNA molecules
- Index of contributors
- Subject index
