Early Brain Damage V2

ContributorsPrefaceContents of Volume 1I. Anatomy and Physiology 1. Neuronal Reaction to Injury during Development Introduction to the Field Cytological Maturation Related to Nature of Response to Injury Considerations in Comparing Results and Drawing Conclusions Summary Statements References 2. Embryonic Dopaminergic Neurons in Culture and as Transplants Introduction Embryonic Dopaminergic Neurons in Primary Monolayer Cultures Embryonic Dopaminergic Neurons in Three-Dimensional Aggregate Cultures Transplantation of Embryonic Dopaminergic Neurons into Adult Rodent Brains References 3. Lesion-Induced Sprouting in the Red Nucleus at the Early Developmental Stage Introduction Sprouting and Formation of New Synapses in Red Nucleus Neurons following Ipsilateral Cerebral Cortex Lesions Effect of Ganglioside Application on Synaptic Plasticity References 4. Multiple Effects of Lesions on Brain Structure in Young Rats Introduction Some Historical Background Our Earlier Work on This Problem Procedures Results Discussion Conclusions ReferencesII. Behavioral Biology 5. A New Perspective for the Interpretation of Early Brain Damage Introduction Secondary Reactions after Brain Damage in Adult Animals Sources of Potential Age-Related Differences in Secondary Reactions after Brain Damage Needs and Behavioral Strategies of Young Animals Assessing the Effects of Early Brain Damage Summary and Conclusions References 6. Early Brain Damage and Time Course of Behavioral Dysfunction: Parallels with Neural Maturation Introduction Age-Brain-Damage Relationship: The Lateral Hypothalamus Relationship between Development of the Lateral Hypothalamus, Brain Damage, and Behavioral Dysfunction Conclusions References 7. Behavioral and Anatomical Studies of Rats with Complete or Partial Decortication in Infancy Introduction The Role of Subcortical Structures in Sparing The Role of Cortical Structures in Sparing Conclusions References 8. Functional Development of the Prefrontal System Introduction The Prefrontal System: Anatomical Relationships Immediate Effects of Early Damage Long-Term Effects of Early Damage Maturation of Prefrontal Connections Summary and Conclusions References 9. The Effects of Early Cerebellar Hemispherectomy in the Rat: Behavioral; Neuroanatomical, and Electrophysiological Sequelae Introduction The Effects of Cerebellar Hemispherectomy at Early and Later Ages on Locomotor Behavior Quantitative Relations between Aberrant and Normal Cerebellorubral Connections Electrical Activity in the Red Nuclei after Early Cerebellar Hemispherectomy Conclusion References 10. Neonatal Cerebral Hemispherectomy: A Model for Postlesion Reorganization of the Brain Introduction Neurological and Behavioral Studies Anatomical Studies Discussion Conclusions References 11. Bases of Recoveries from Perinatal Injuries to the Cerebral Cortex Introduction Our First Approaches to the Problem Nature of the Spatial Vision of Decorticated Mammals The Equipotential Function of the Cerebral Cortex Effects of Early Injuries to the Holistic System Reflections, Suggestions, and Conclusions References 12.