Every Coin Has Two Sides
An Introduction to Causal Inference in Pharmaceutical Statistics
Yixin Fang(Author)
Chapman and Hall (Publisher)
1st Edition
Will be published approx. on 20. August 2026
392 pages
E-Book
978-1-040-65184-1 (ISBN)
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Description
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Every Coin Has Two Sides: An Introduction to Causal Inference in Pharmaceutical Statistics introduces basic and advanced statistical inference methods and causal inference methods relevant to pharmaceutical statics. This book distills seventy fundamental ideas and concepts-symbolized as gold coins, each with two sides-essential for mastering asymptotic statistics, causal inference, semiparametric statistics, and targeted learning. This book covers causal thinking that has increasingly become important in the planning, design, conduct, analysis, and interpretation of clinical studies. Progressing from basic statistical concepts to advanced targeted learning techniques, the book highlights the fusion of two cultures of statistical modelling. This book is suitable for graduate students in statistics, biostatistics, public health, and data science who are looking to pursue a career in the pharmaceutical industry, as well as for clinical statisticians and epidemiologists working in the pharmaceutical industry.
Key Features:
Causal inference book for clinical statisticians in the pharmaceutical industry and graduate students
Introduction to asymptotic statistics, causal inference, semiparametric statistics, and targeted learning
Aligning with FDA and ICH guidance documents and covering different stages of clinical studies
Seventy fundamental ideas and concepts-symbolized as gold coins, each with two sides
Key Features:
Causal inference book for clinical statisticians in the pharmaceutical industry and graduate students
Introduction to asymptotic statistics, causal inference, semiparametric statistics, and targeted learning
Aligning with FDA and ICH guidance documents and covering different stages of clinical studies
Seventy fundamental ideas and concepts-symbolized as gold coins, each with two sides
More details
Series
Edition
1. Auflage
Language
English
Place of publication
London
United Kingdom
Publishing group
Taylor & Francis Ltd
Target group
Professional and scholarly
Product notice
Reflowable
Illustrations
17 Tables, black and white; 8 Line drawings, color; 27 Line drawings, black and white; 8 Illustrations, color; 27 Illustrations, black and white
ISBN-13
978-1-040-65184-1 (9781040651841)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions

Book
approx. 08/2026
1st Edition
CRC Press
€136.50
Not yet published
Person
Yixin Fang is Director of Statistics and Senior Research Fellow at AbbVie Inc. He obtained his Ph.D. in Statistics from Columbia University and is an experienced statistician and data scientist who has a history of working in both the biopharmaceutical industry and academia. He is an elected Fellow of the American Statistical Association.
Content
Preface I An Introduction to Asymptotic Statistics 1 The Number Two 2 Fundamentals of Asymptotic Statistics 3 Statistical Inference 4 Maximum Likelihood Estimation (MLE) 5 Minimum Loss Estimation (MLE) II An Introduction to Causal Inference 6 Potential Outcomes 7 Study Designs 8 Estimand 9 Estimator 10 Sensitivity Analysis III An Introduction to Semiparametric Statistics 11 Regular and Asymptotically Linear Estimator 12 Efficient Influence Function 13 A Convenient Approach 14 Missing Data 15 Longitudinal Data IV An Introduction to Targeted Learning 16 Super Learning 17 Targeted Learning 18 Implementation 19 Intercurrent Events 20 Fusion of Two Cultures Bibliography Index
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