
The Enzymes
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Content
- Front Cover
- The Enzymes: Group Transfer
- Copyright Page
- Contents
- List of Contributors
- Preface
- Contents of Other Volumes
- Chapter 1. Adenylyl Transfer Reactions
- I. Introduction
- II. Carboxyl Group Activation
- III. Biosynthesis of Phosphodiester Derivatives of Adenosine
- IV. Synthesis of Adenosine Diphosphate Derivatives
- V. Sulfate Activation
- VI. Synthesis of Imidol Adenylate Derivatives
- VII. Adenylylation of Functional Groups of Proteins
- Chapter 2. Uridine Diphosphoryl Glucose Pyrophosphorylase
- I. Introduction
- II. Metabolic Function
- III. Properties
- Chapter 3. Adenosine Diphosphoryl Glucose Pyrophosphorylase
- I. Introduction
- II. Classification of ADPglucose Pyrophosphorylases
- III. Kinetic Properties of the ADPglucose Pyrophosphorylases
- IV. Physical Properties of the ADPglucose Pyrophosphorylases
- Chapter 4. The Adenosyltransferases
- I. Introduction
- II. Methionine Adenosylitransferase
- III. B12s Adenosyltransferase
- IV. Conclusion
- Chapter 5. Acyl Group Transfer (Acyl Carrier Protein)
- I. Introduction
- II. Acyl Carrier Protein
- III. Malonyl CoA-ACP Transacylase
- IV. Acetyl CoA-ACP Transacylase
- V. ß-Ketoacyl ACP Synthetase
- Chapter 6. Chemical Basis of Biological Phosphoryl Transfer
- I. Introduction
- II. Hydrolysis of Acyclic Phosphate Esters
- III. Nucleophilic Reactions at Acyclic Phosphorus
- IV. Pentacovalency and Pseudorotation
- V. Catalysis of Phosphoryl Transfer or Ligand Loss
- VI. Enzymic Catalytic Mechanisms
- Chapter 7. Phosphofructokinase
- I. Introduction
- II. Purification
- III. Assay of Phosphofructokinase Activity
- IV. Catalytic Properties
- V. Structural Properties
- VI. Regulatory Properties of PFK
- VII. Role of Specific Groups in Enzymic Activity
- VIII. The Role of PFK in the Control of Glycolysis
- Chapter 8. Adenylate Kinase
- I. Biological Aspects
- II. Molecular Properties
- III. Catalytic Properties
- Chapter 9. Nucleoside Diphosphokinases
- I. Introduction
- II. Molecular Properties
- III. Catalytic Properties
- IV. Functions in the Cell
- Chapter 10. 3-Phosphoglycerate Kinase
- I. Introduction
- II. Biological Behavior of Phosphoglycerate Kinase
- III. Isolation and Molecular Properties
- IV. Reaction Kinetics
- V. Conclusion
- Chapter 11. Pyruvate Kinase
- I. Introduction
- II. Molecular Properties
- III. Catalytic Properties
- Chapter 12. Creatine Kinase (Adenosine 5'-Triphosphate-Creatine Phosphotransferase)
- I. Introduction
- II. Structure
- III. Purification, Assay, and Enzyme Stability
- IV. Substrate Specificity
- V. The Activating Metal Ion
- VI. Enzyme Kinetics
- VII. Chemical Investigations of the Enzyme Mechanism
- Chapter 13. Arginine Kinase and Other Invertebrate Guanidino Kinases
- I. Introduction
- II. Determination of Enzymic Activity
- III. Molecular Properties
- IV. Catalytic Properties
- V. Reaction Mechanism
- VI. Equilibrium
- Chapter 14. Glycerol and Glycerate Kinases
- I. Introduction
- II. Glycerol Kinases
- III. D-Glycerate Kinases
- Chapter 15. Microbial Aspartokinases
- I. Introduction
- II. Escherichia coli Aspartokinases
- III. Other Coliform Bacteria
- IV. Aspartokinases Regulated by Concerted Feedback Inhibition
- V. Rhodopseudomonas spheroides
- VI. Saccharomyces cerevisiae
- Chapter 16. Protein Kinases
- I. Introduction
- II. Substrate-Specific Protein Kinases
- III. Cyclic Nucleleotide-Regulated Protein Kinases
- IV. Nonclassified Protein Kinases
- Author Index
- Subject Index
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