
The Enzymes
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Content
- Front Cover
- The Enzymes: Hydrolysis
- Copyright Page
- Contents
- List of Contributors
- Preface
- Contents of Other Volumes
- Chapter 1. The Hydrolysis of Sulfate Esters
- I. Introduction
- II. Sulfatases
- III. Sulfatophosphate Sulfohydrolases
- IV. Sulfamatases
- Chapter 2. Arylsulfatases
- I. Introduction
- II. Type I Arylsulfatases
- III. Type II Arylsulfatases
- IV. General Considerations
- Chapter 3. Carboxylic Ester Hydrolases
- I. Introduction
- II. Molecular Properties of Carboxylesterases (EC 3.1.1.1)
- III. Catalytic Properties
- IV. Some Other Individual Esterases
- Chapter 4. Phospholipases
- I. Introduction
- II. Phospholipase A2
- III. Phospholipase C
- Chapter 5. Acetylcholinesterase
- I. Introduction
- II. Molecular Properties
- III. The Catalytic Mechanism
- Chapter 6. Plant and Animal Amylases
- I. Introduction
- II. Assay Methods
- III. Origins, Purification, and Molecular Variants
- IV. Composition, Structure, and Modification
- V. pH, Temperature, and Salt Effects
- VI. Mechanism of Action
- VII. Action Pattern
- VIII. Biosynthesis, Genetics, and Control
- Chapter 7. Glycogen and Starch Debranching Enzymes
- I. Introduction
- II. Direct Debranching Enzymes
- III. Indirect Debranching Enzymes
- IV. Characterization of a Debranching Enzyme or Enzyme System
- V. The in Vivo Roles of Direct and Indirect Debranching Enzymes
- VI. The Use of Debranching Enzymes in the Structural Determination of Glycogen and the Starch Components
- Chapter 8. Bacterial and Mold Amylases
- I. Introduction
- II. Molecular Properties
- III. Catalytic Properties
- Chapter 9. Cellulases
- I. Introduction
- II. Significance and Distribution
- III. Assay and Detection
- IV. Induction and Repression
- V. Production and Isolation
- VI. "C1" Factors
- VII. Physical and Chemical Properties of Cellulases
- VIII. Substrate Binding and Catalytic Properties
- IX. Action of Cellulases on Cellulose and Related Substrates
- X. Applications
- Chapter 10. Yeast and Neurospora lnvertases
- I. Introduction
- II. Yeast Invertase
- III. Neurospora Invertase
- Chapter 11. Hyaluronidases
- I. Introduction
- II. The Substrates
- III. Prominent Hyaluronidases
- IV. Preparation and Assay of Hyaluronidases
- V. Properties of Hyaluronidases
- VI. Kinetics of Hyaluronidases
- VII. Biological Effects of Hyaluronidases
- Chapter 12. Neuraminidases
- I. Historical Data on the Recognition of the Enzymes
- II. Occurrence
- III. Purification of the Enzyme
- IV. Properties of the Enzyme
- V. Substrate Specificity and Neuramidases
- VI. Kinetic Data of Neuraminidases
- VII. Inhibitors of Neuraminidase Activity
- VIII. Assay Method
- IX. Biological Significance of Neuraminidase
- Chapter 13. Phage Lysozyme and Other Lytic Enzymes
- I. Introduction
- II. The Lytic Enzymes of Escherichia coli Phages
- III. Lytic Enzymes of Other Gram-Negative Bacteriophages
- IV. Lytic Enzymes of Gram-Positive Bacteriophage
- Chapter 14. Aconitase
- I. Introduction
- II. Molecular Properties
- III. Catalytic Properties
- Chapter 15. ß-Hydroxydecanoyl Thioester Dehydrase
- I. Introduction
- II. Substrate Specificity
- III. Reaction Mechanism
- IV. Protein Structure and Active Site
- V. Dehydrase Inhibition by Substrate Analogs
- VI. Dehydraseless Mutants
- VII. Distribution of Dehydrase
- Chapter 16. Dehydration in Nucleotide-Linked Deoxysugar Synthesis
- I. Introduction
- II. The dTDP-D-Glucose Oxidoreductase
- III. Other Nucleoside Diphosphate Sugar Oxidoreductases
- IV. Synthesis of 3,6-Dideoxyhexoses
- Chapter 17. Dehydrations Requiring Vitamin B12 Coenzyme
- I. Introduction
- II. Chemistry of Substrate to Product Interconversion
- III. The Nature of the Hydrogen Transfer
- IV. Enzyme-Coenzyme Interaction
- V. Interaction with B12 Coenzyme Analogs
- VI. Properties of the Apoenzyme
- Chapter 18. Enolase
- I. Introduction
- II. Molecular Properties
- III. Catalytic Properties
- Chapter 19. Fumarase and Crotonase
- I. Fumarase
- II. Crotonase
- Chapter 20. 6-Phosphogluconic and Related Dehydrases
- I. Introduction
- II. Metal Ion-Assisted Dehydrations
- III. Schiff Base-Assisted Dehydrations
- Chapter 21. Carbonic Anhydrase
- I. Introduction
- II. Molecular Properties
- III. Catalytic Properties
- Author Index
- Subject Index
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