The Enzymes
Academic Press
3rd Edition
Published on 27. February 1971
558 pages
978-0-08-086578-2 (ISBN)
Description
The Enzymes
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Other editions
Additional editions
Paul D. Boyer | etc.
Enzymes: v. 1
Book
01/1970
3rd Edition
Academic Press
€90.37
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Previous edition
Ross Dalbey | Carla Koehler | Fuyuhiko Tamanoi
The Enzymes
Molecular Machines Involved in Protein Transport across Cellular Membranes
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08/2007
Academic Press
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Content
- Front Cover
- The Enzymes Structure and Control, Volume I
- Copyright Page
- Contents
- List of Contributors
- Preface
- Contents of Other Volumes
- Chapter 1. X-Ray Crystallography and Enzyme Structure
- I. Introduction
- II. Enzyme Crystals
- III. X-Ray Diffraction and Principles of Protein Structure Analysis
- IV. X-Ray Diffraction Studies of Globular Macromolecules
- V. Summary and Conclusions
- Glossary of Symbols
- Chapter 2. Chemical Modification by Active-Site-Directed Reagents
- I. Nature of Affnnity Labeling and Its Relationship to Chemical Modification in General
- II. Modification of Serine Proteases by Active-Site-Directed Reagents
- III. Active Center Labeling of Other Enzymes by Directed Reagents
- IV. Particular Usefulness of Active-Site-Directed Reagents
- V. Conclusions
- Chapter 3. Chemical Modification as a Probe of Structure and Function
- I. Introduction
- II. Principles of Chemical Modification
- III. Methodology
- IV. Modification as a Probe of Structure
- V. Modification as a Probe of Function
- VI. Other Uses of Chemical Modification
- VII. Discussions of Specific Enzymes
- VIII. Conclusions
- Chapter 4. Multienzyme Complexes
- I. Introduction
- II. a-Ketoacid Dehydrogenase Complexes
- Ill. Fatty Acid Synthetases
- IV. Multienzyme Complexes in the Biosynthesis of Aromatic Amino Acids
- V. Biological Significance of Multienzyme Complexes
- Chapter 5. Genetic Probes of Enzyme Structure
- I. Introduction
- II. Genes and Mutations
- III. Specific Examples of Mutationally Altered Proteins
- IV. Amino Acid Analogs
- V. Advantages and Limitations of Mutants
- Chapter 6. Evolution of Enzymes
- I. General Considerations-Evolutionary and Structure-Function Relationships in Proteins
- II. Some Principles from the Study of Cytochrome c
- III. Expressions of Genetic Phenomena in Protein Structure
- IV. Expression of Evolutionary Factors in Protein Structure
- Chapter 7. The Molecular Basis for Enzyme Regulation
- I. Introduction
- II. Qualitative Features of Molecular Models
- III. Quantitative Molecular Parameters for Regulatory Proteins
- IV. Diagnostic Tests
- V. Molecular Properties of Allosteric Proteins
- VI. Conclusions
- VII. Glossary
- Chapter 8. Mechanisms of Enzyme Regulation in Metabolism
- I. Introduction
- II. Principles of Metabolic Regulation
- III. Regulation of Balance between Metabolic Functions
- IV. Feedback Regulation of Multifunctional Pathways
- Chapter 9. Enzvmes as Control Elements in Metu bolic Regulation
- I. Introduction
- II. Analogy between Metabolic and Electronic Systems
- III. Physiological Function and Design Requirements
- IV. Summary
- Author Index
- Subject Index
