Introducing Epigenetics
Description
Epigenetics is the most exciting field in biology today, developing our understanding of how and why we inherit certain traits, develop diseases and age, and evolve as a species.
This non-fiction comic book introduces us to genetics, cell biology and the fascinating science of epigenetics, which is rapidly filling in the gaps in our knowledge, allowing us to make huge advances in medicine. We'll look at what identical twins can teach us about the epigenetic effects of our environment and experiences, why certain genes are 'switched on' or off at various stages of embryonic development, and how scientists have reversed the specialization of cells to clone frogs from a single gut cell.
In Introducing Epigenetics, Cath Ennis and Oliver Pugh pull apart the double helix, examining how the epigenetic building blocks and messengers that interpret and edit our genes help to make us, well, us.
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Content
- Intro
- Title Page
- Copyright
- Contents
- Genes, RNA and Proteins
- Chromosomes, Nucleosomes and Chromatin
- DNA Replication and Mitosis
- Meiosis and Inheritance
- Beyond the DNA Sequence: Gene Regulation
- Nature and Nurture
- Twin Studies
- The History of Epigenetics
- The Modern Understanding of Epigenetic Modifications
- DNA Methylation
- Histone Modifications
- Chromatin Remodelling
- Nuclear Location
- RNA
- Interactions Between Different Epigenetic Modifications
- Epigenetics Explains What Genetics Alone Cannot
- Epigenetic Changes During Embryonic Development
- X Chromosome Inactivation
- How Our Environment Affects Our Genes
- Not So Identical Twins
- Epigenetic Inheritance
- Epigenetic Inheritance in Animal Models
- Human Epigenetic Inheritance: The Dutch Hunger Winter
- Human Epigenetic Inheritance: Överkalix
- Mechanisms of Epigenetic Inheritance
- Epigenetics in Evolution
- Epigenetics in Disease: Ageing
- Epigenetics in Disease: Inherited Mutations in Epigenetic Regulators
- Epigenetics in Disease: Imprinting Errors
- The Epigenetics of Cancer
- Epigenetics in Medicine
- Stem Cell Therapies
- Epigenetics and Pseudoscience
- The Future of Epigenetics
- Epigenomics
- New Epigenetic Modifications
- The Epitranscriptome
- Epigenetic Editing
- Epigen-Ethics
- Looking Ahead
- Glossary
- Recommended Further Reading
- Author's Acknowledgements
