Drug Utilization Research
Description
Reviews / Votes
"Overall, this is a great resource for healthcare providers and a great learning tool for students. It is well written and includes many helpful figures and tables. The references to specific pages for more in-depth explanations of certain topics make this book very user friendly." (Doody Enterprises, 2016)More details
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Persons
Monique Elseviers, Centre for Research and Innovation in Care, University of Antwerp, Belgium.
Björn Wettermark, Associate Professor in Pharmacoepidemiology, Karolinska Institutet, Stockholm, Sweden.
Morten Andersen, Visiting Professor, Centre for Pharmacoepidemiology, Karolinska Institutet, Stockholm, Sweden; Senior Physician at the Department of Clinical Pharmacology, Karolinska University Hospital, Stockholm, Sweden; Senior Researcher at the Research Unit for General Practice, University of Southern Denmark, Denmark.
Ria Benko, Associate Professor, Department of Clinical Pharmacy at the University of Szeged, Hungary.
Marion Bennie, Professor of Pharmacy Practice, University of Strathclyde, UK; Chief Pharmaceutical Adviser, NHS National Services Scotland, UK.
Brian Godman, Research Scientist, Karolinska Institutet, Stockholm, Sweden.
Janet Krska, Professor of Clinical and Professional Pharmacy, Medway School of Pharmacy, Universities of Greenwich and Kent, UK.
Elisabetta Poluzzi, Assistant Professor of Pharmacology, Department of Pharmacology, Faculty of Medicine, University of Bologna, Italy.
Katja Taxis, Associate Professor of Pharmacotherapy and Clinical Pharmacy, University of Groningen, Netherlands.
Vera Vlahovic-Palcevski, Professor, Department of Pharmacology, University of Rijeka Medical School, Croatia; Specialist in Clinical Pharmacology, University Hospital Rijeka, Croatia.
Robert Vander Stichele, practicing family physician in Ghent, Belgium.
Content
List of contributors viii
Acknowledgements xiv
About the companion website xix
Part 1 Introduction
1 Introduction to drug utilization research 3 Björn Wettermark, Monique Elseviers, Anna Birna Almarsdóttir, Morten Andersen, Ria Benko, Marion Bennie, Irene Eriksson, Brian Godman, Janet Krska, Elisabetta Poluzzi, Katja Taxis, Robert Vander Stichele, Vera Vlahovic-Palcevski
Part 2 Methodology
2 Study designs in drug utilization research 15 Björn Wettermark, Mirko Di Martino, Monique Elseviers
3 Primary data collection for drug utilization research 29 Tatiana Chama Borges Luz, Evalill Nilsson
4 Secondary data sources for drug utilization research 39 Irene Eriksson, Luisa Ibáñez
5 Classifi cation systems for drugs and diseases 49 Marit Rønning, Stuart McTaggart
6 Measurement units of drug utilization 58 Hege Salvesen Blix
7 Individual-level drug utilization analyses 68 Jesper Hallas, Henrik Støvring, Anton Pottegård
8 Measurement of drug expenditure 77 Sabine Vogler, Jaana E. Martikainen
9 Basic statistical methods in drug utilization research 88 Douglas T. Steinke, Monique Elseviers
10 Visualization of drug utilization data 99 Maria Matuz, Ria Benko, Mikael Hoffmann
11 Multilevel analyses in drug utilization research 116 Juan Merlo
12 Defi ning and developing quality indicators for drug utilization 126 Stephen Campbell, Björn Wettermark, Morten Andersen
13 Qualitative methods in drug utilization research 139 Anna Birna Almarsdóttir, Pia Bastholm Rahmner
Part 3 Applied drug utilization research
Section A Comparative drug utilization research
14 Comparison of drug utilization across different geographical areas 153 Vera Vlahovic-Palcevski, Björn Wettermark, Luisa Ibáñez, Robert Vander Stichele
15 Comparison of drug utilization in different health care settings 160 Sean MacBride-Stewart, Ksenia Zagorodnikova, Irene Langner, Gisbert W. Selke
16 Time-dependent and seasonal variations in drug utilization 173 Eric Van Ganse, Laurent Laforest, Niels Adriaenssens
17 Comparative studies of patient and prescriber characteristics 184 Irene Eriksson, Ulf Bergman, Vera Vlahovic-Palcevski, Mia von Euler
18 Comparative studies of health systems 194 Tatiana Chama Borges Luz, Claudia Garcia Serpa Osorio-de-Castro, Björn Wettermark
Section B Drug utilization and health policy
19 Drug utilization and health policy 203 Brian Godman, Hye Young Kwon, Marion Bennie, Anna Birna Almarsdóttir
20 Managed introduction of new drugs 210 Brian Godman, Roberta Joppi, Marion Bennie, Saira Jan, Björn Wettermark
21 Management of drugs in the health care system 222 Brian Godman, Marion Bennie, Claudia Garcia Serpa Osorio-de-Castro, Vu Thi Thu Huong, Saira Jan
22 The pharmaceutical industry and health policy 231 Richard Torbett, Donald Han, Indranil Bagchi
Section C Drug utilization in specific populations
23 Drug utilization in pregnant women 240 Hedvig Nordeng
24 Drug utilization in the paediatric population 248 Antje Neubert, Katja Taxis, Ian C.K. Wong
25 Drug utilization in older people 259 Katja Taxis, David O'Sullivan, Shane Cullinan, Stephen Byrne
Section D Drug utilization in specific therapeutic areas
26 Drug utilization research in the area of antibiotics 270 Ria Benko, Marion Bennie, Samuel Coenen
27 Drug utilization research in the area of cardiovascular medicines 284 Elisabetta Poluzzi, Maarit Jaana Korhonen
28 Drug utilization research in the area of analgesics and psychotropics 294 Helga Zoëga, Alesha Smith, Nadia Barozzi
29 Drug utilization research in the area of biologicals 302 Carlo Piccinni, Luigi Naldi, Martin Neovius
30 Drug utilization research in the area of cancer drugs 315 Nils Wilking, Thomas Hofmarcher, Ulla Wilking, Bengt Jönsson
Section E Determinants of drug utilization
31 Health system perspectives 328 Paul Spivey, Brian Godman
32 Prescriber perspectives 336 Colin Bradley, Kathleen Holloway, Janet Krska
33 Patient perspectives 347 Janine Traulsen, Nicky Britten, Janet Krska
Section F Adherence and drug utilization research
34 An introduction to adherence research 355 Bernard Vrijens
35 Assessment of medication adherence in field research 361 Monique Elseviers, Bernard Vrijens
36 Assessment of adherence to drug treatment in database research 369 Jean-Pierre Grégoire, Jocelyne Moisan
37 Interventions to improve adherence to drug treatment 381 Marie-Paule Schneider, Jennifer Celio, Yoleen van Camp, Matthias Cavassini
Section G The role of drug utilization within the field of pharmacoepidemiology
38 Drug utilization research and risk management 392 Giampiero Mazzaglia, Peter Mol
39 Drug utilization research and pharmacovigilance 399 Emanuel Raschi, Fabrizio De Ponti
40 Drug utilization research and the regulator's perspective in pharmacovigilance 408 Xavier Kurz, Kevin Blake
41 Drug utilization research and outcomes research 417 Henrik Toft Sørensen, Gianluca Trifi rò
42 Drug utilization research and pharmacoeconomics 425 Cara Usher, Kathleen Bennett, Lorenzo G. Mantovani, Dyfrig Hughes
Section H Assessment and improvement of the quality of medicine use
43 Assessment of quality of prescribing using quality indicators 433 Petra Denig, Flora Haaijer-Ruskamp, Lisa Pont
44 Quality indicators for patient care in pharmacy practice 443 Hanne Herborg
45 Interventions that infl uence prescribing decisions and drug utilization 460 Jens Søndergaard, Dorte Gilså Hansen, Debra Rowett
46 Development, delivery and evaluation of implementation programmes 468 Elizabeth Roughead, Andrew Gilbert
47 Towards a better understanding of prescribingenhancement interventions 477 Frank May
Part 4 Epilogue
48 The many futures of drug utilization research 489 Hubert G.M. Leufkens, Frank May, Nicky Britten
Glossary 492
Index 497
