Epilepsy
Description
Comprehensive, cutting-edge guide to adult epilepsy from the renowned Queen Square specialists
Epilepsy: A Queen Square Textbook delivers an authoritative and up-to-date overview of the causes, consequences, diagnosis, and treatment of epilepsy in adults. Written by the distinguished Queen Square Epilepsy group, this complete resource synthesises the relevant evidence and applies the latest knowledge to clinical practice, with points of practical importance highlighted throughout.
This essential reference covers:
- Fundamental aspects: The neurosciences of epilepsy and epileptogenesis, neurophysiology, medical imaging, epidemiology, genetics and the spectrum of epileptic seizures and epilepsies
- Clinical management: Diagnosis, medical and surgical treatment, neuropsychology, non-pharmacological therapies, status epilepticus, reproduction, epilepsy in older people, sleep, and neurodegeneration
- Current challenges: Psychiatric and somatic comorbidities, sudden unexpected death in epilepsy (SUDEP), functional dissociative seizures, driving and the law
- Contemporary issues and emerging technologies: Climate change impacts, the role of artificial intelligence in diagnosis and treatment, and future perspectives in epilepsy management
Epilepsy: A Queen Square Textbook is an indispensable resource for healthcare professionals involved in epilepsy care and research, including neurologists, nurses, neuroscientists, and psychologists-from trainees through to established specialists.
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Persons
JOHN S. DUNCAN is Professor of Neurology at UCL Queen Square Institute of Neurology and Consultant Neurologist at the National Hospital for Neurology and Neurosurgery. He serves as Governor of UCLH NHS Foundation Trust and Chair of the Scientific Advisory Committee for the Epilepsy Research Institute. Previously, he was Chair of ILAE Neuroimaging and Diagnostic Methods Committees, Medical Director of Epilepsy Society, Clinical Director of Queen Square Division of UCL Hospitals, Head of Department of Epilepsy at the Institute of Neurology, and President of the British branch of ILAE.
LEY SANDER is Professor of Neurology at UCL Queen Square Institute of Neurology, Consultant Neurologist at the National Hospital for Neurology and Neurosurgery, and Professor of Neurology at West China School of Medicine, Sichuan University, Chengdu, China. He is a Trustee of SUDEP Action and serves on the Editorial Board of The Lancet Neurology. Previously, he was Head of Department of Epilepsy at the Institute of Neurology, Member of the Management Committee of the International League Against Epilepsy, Member of the Executive Committee of the International Bureau for Epilepsy, Medical Director of Epilepsy Society, Director for Research & Development at Stichting Epilepsie Instellingen Nederland (SEIN), and Director of the WHO Centre for Research & Training in Neurosciences.
Content
About the Editors vii
List of Contributors ix
Forewords xi
Preface xiv
Acknowledgements xvi
1 What Is Epilepsy? 1
2 Epidemiology and Natural History 6
3 The Spectrum of Seizures and Epilepsies 14
4 Risk Factors for Epilepsy 31
5 Genetics of Epilepsy 43
6 Neuroscience of Epilepsy 50
7 Neurophysiology 60
8 Neuroimaging 77
9 The Role of Neuropsychology in the Management of People with Epilepsy 95
10 First Seizure Clinic, Differential Diagnosis 104
11 Medical Treatment 112
12 Dietary, Psychological and Complementary Therapies 147
13 Epilepsy in the Acute Medical Unit 151
14 Status Epilepticus 159
15 Epilepsy Surgery 167
16 Epilepsy and Reproduction 183
17 Epilepsy in Later Life 193
18 Sleep and Epilepsy 199
19 Epilepsy, Driving, and the Law 206
20 Climate Change and Epilepsy 215
21 Premature Mortality and Sudden Unexpected Death in Epilepsy 219
22 Epilepsy and Neurodegeneration 225
23 Neuropsychiatric Aspects of Epilepsy 235
24 Functional Dissociative Seizures 241
25 Big Data and Artificial Intelligence 252
26 Future Perspectives for Epilepsy 266
Index 274
