Pre-Analytics of Pathological Specimens in Oncology
1st Edition
Published on 30. January 2015
VI, 133 pages
978-3-319-13957-9 (ISBN)
Description
This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase - the period from surgical removal of tissue to the start of pathological processing - have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up.
More details
Series
Language
English
Place of publication
Cham
Switzerland
Publishing group
Springer International Publishing
Target group
Professional and scholarly
Product notice
Reflowable
Illustrations
VI, 133 p. 65 illus., 61 illus. in color.
File size
7,26 MB
ISBN-13
978-3-319-13957-9 (9783319139579)
DOI
10.1007/978-3-319-13957-9
Schweitzer Classification
Other editions
Additional editions
Manfred Dietel | Christian Wittekind | Gianni Bussolati
Pre-Analytics of Pathological Specimens in Oncology
Book
03/2015
Springer
from
€53.49
Shipment within 10-15 days
Content
What Is Pre-Analytics in Surgical Pathology? .- Histologic Validation of Vacuum Sealed Formalin.- Free Tissue Preservation and Transport System .- Pre-Analytics and Molecular Pathology.- Experiences in Vacuum Preparation of Routine Specimens.- Tissue Heterogeneity as a Pre-Analytical Source of Variability.- Vacuum Fixation of Breast Specimens Before Grossing.- How Do Short Fixation and Rapid Microwave Processing Affect Her2 Testing?.- Current Projects in Pre-Analytics - Where to Go?.- Nucleic Acid Extraction from FFPE Tissue as Critical Preanalytic Step for NGS Applications.- Experiences With Pre-Analytics of Lung Specimen.- Experiences With Pre-Analytics of GI-Specimen.- Bone Marrow Work-Up.- Two-Temperature Fixation Preserves Activation Status with High Efficiency.- Towards the Lean Lab. The Industry Challenge.
