Functional Biochemistry of Metallic Elements
Description
This book explores the important role of trace elements in human health, including trace minerals, toxic trace elements, and major minerals. Essential trace elements are needed in small amounts for normal body functions, but both their deficiency and excess can harm health.
International experts study how different metallic elements, cations and micronutrients affect cell function. Using multidisciplinary approaches to cover the biochemical, physiological, and nutritional aspects of these elements, they give a deep understanding of how these minerals impact cellular and molecular processes related to health and disease.
The book is a valuable resource for health professionals, nutritional scientists, medical students, fellows, residents, and graduate students. It focuses on the functional biochemistry of specific metallic elements in various cell systems, providing current insights into how different metals regulate cell functions. Readers will gain knowledge about the importance of metallic minerals and trace elements. The insights from international authors will help advance understanding of how trace minerals can prevent diseases and address global health issues.
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Dr. Naranjan S. Dhalla
has published more than 687 full-length papers in refereed journals and 205 papers in books and monographs. His research work has been cited more than 36,856 times (h-index of 89), and he edited 68 books on various aspects of the cardiovascular system. He has been an invited speaker at more than 413 national and international conferences and 151 institutions. Dr. Dhalla has trained more than 166 graduate students, postdoctoral fellows and visiting scientists. In his capacity as Secretary General and President of the International Society for Heart Research, he was engaged in promoting the scientific basis of cardiovascular medicine for 25 years. He has been Editor-in-Chief of a major international journal, Molecular and Cellular Biochemistry, for the past 35 years and has also served as Executive Director of the International Academy of Cardiovascular Sciences since 1996. He has received 225 honours and awards from all over the world, including MD/DSc Honorary Degrees from 7 Institutions and Professor Honarari Causa from 4 Universities. He is a Fellow of the Royal Society of Canada and was inducted into the Canadian Medical Hall of Fame as well as the Winnipeg Citizen Hall of Fame. Dr. Dhalla is Honorary Life President of the IACS and is serving as Distinguished Professor, University of Manitoba and Director of Cardiovascular Developments at the St. Boniface Hospital Albrechtsen Centre, Winnipeg, Manitoba.
Dr. Paramjit S. Tappia
has over 30 years of research experience, with a particular interest in nutrition, biomarkers , and subcellular and molecular mechanisms of human disease . He received his B.Sc. (Honors) in Pharmacology from the University of Sunderland, U.K. in 1985 and Ph.D. in Biochemistry from the University of Wolverhampton, U.K. in 1992. He received postdoctoral training at the Institute of Human Nutrition, University of Southampton, U.K. from 1992-1995. In 1996, he joined the Institute of Cardiovascular Sciences, St. Boniface Hospital Albrechtsen Research Centre, Winnipeg, Canada, as a Research Associate. He is currently a Principal Investigator and Clinical Scientist in the Asper Clinical Research Institute, St. Boniface Hospital. To date, he has published 143 full-length peer-review papers with an H-index of 39, and 43 book chapters in the field of cardiovascular sciences and nutrition. He has edited 9 books and currently serves as Associate Editor of Molecular and Cellular Biochemistry and is on the Editorial Boards for 4 other international journals. Dr. Tappia also serves as Editor-in-Chief of CV Network, which is the official news bulletin of the International Academy of Cardiovascular Sciences. Dr. Tappia has served on the scientific advisory boards as well as on organizing committees for several international meetings and has successfully trained several undergraduate and graduate students, technicians, and post-doctoral fellows.
Dr. Anureet K. Shah received her B.Sc. in Biotechnology from HMV college (Jallandhar) affiliated to Guru Nanak Dev University of India, in 2006 and M.Sc. in Biotechnology from SD College (Chandigarh) affiliated to Panjab University of India in 2008. She earned her Ph.D. in Nutrition from the Texas Woman's University of Dallas (Texas), U.S.A in 2014. In 2018, Dr. Shah joined California State University, Los Angeles (CSULA) as an Assistant Professor of Nutritional Sciences in the Department of Nutrition and Food Sciences. She is currently an Associate Professor, Principal Investigator, and Scientist in the Department of Nutritional Sciences, working in collaboration with the Biochemistry Department at CSULA. Dr. Shah has an extensive publication record, including numerous full-length papers in scientific journals and several book chapters in the area of cardiovascular sciences and nutrition. To date, she has published 25 full-length peer-review papers and 18 book chapters in the field of nutritional biochemistry and human health. She has also edited 4 books and currently serves on the Editorial Boards for 3 international journals.
Content
Part I. Trace Elements in Health and Disease .- Chapter 1. Modulation of Trace Elements in Pregnant Women and its Clinical Importance for Fetal Development.- Chapter 2. Trace Elements as Molecular Orchestrators of Health and Disease: A Biochemical and Pathophysiological Perspective.- Chapter 3. Trace Minerals (Fe, Zn, Cr, Cu, Se, V, Mn, Mo, Co) in Human Health and Disease.- Chapter 4. Sources and Role of Trace Elements in Nutrition.- Chapter 5. The Neuroprotective Role of Micronutrients: A Systematic Review of Preclinical and Clinical Studies on Antioxidant Vitamins, Essential Minerals, and Trace Elements in Managing Neurodegenerative Diseases.- Chapter 6. Chromium in the Prevention of Diabetes-induced Cardiovascular and Renal Disorders: Where do We Stand Now?.- Chapter 7. The Role of Antioxidant-associated Trace Elements in the Development Diabetic Cardiomyopathy.- Chapter 8. Selenium and the Heart: Molecular Insights into Cardioprotection - A Review.- Chapter 9. The Role of Cadmium in the Development and Progression of Liver Cancer.- Chapter 10. Functional Biochemistry of Trace Elements in Cancer: Mechanisms, Biomarkers, and Therapeutic Potentials.- Part II. Heavy Metals and Major Minerals .- Chapter 11. Heavy Metals for Treating Disease and Maintaining Health.- Chapter 12. Role of Micronutrients in the Treatment of Metal/ Metalloid Toxicity: Mechanisms and Therapeutic Potential.- Chapter 13. Development of Hypertension in Response to Chronic Exposure to Mercury.- Chapter 14. Occupational Lead Exposure and its Association with Reproductive Dysfunctions in Both Genders.- Chapter 15. Essential and Toxic: The Dual Nature of Heavy Metals in Human Physiology.- Chapter 16. Functional Biochemistry of Iron and its Cardio-pulmonary Impact.- Chapter 17. Iron Metabolism and Its Role in Anemia.- Chapter 18. The Involvement of Copper Deficiency in the Pathogenesis of Non-alcoholic Fatty Liver Disease.- Chapter 19. Major Minerals: Cardiometabolic Benefits and their Role in Promoting Healthy Aging.- Chapter 20. Major Minerals (Na, K, Ca, Mg, P) in Physiological Function and Disease.- Chapter 21. Sodium Homeostasis and Roles of Sodium-Dependent Transport in Health.
