Macro Roles for MicroRNAs in the Life and Death of Neurons
1st Edition
Published on 1. December 2009
XII, 121 pages
978-3-642-04298-0 (ISBN)
Description
The discovery of microRNAs has revealed an additional level of fine tuning of the genome and how genes are used again and again in different combinations to generate the complexity that underlies for instance the brain. This book examines this field.
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Bart De Strooper
Macro Roles for MicroRNAs in the Life and Death of Neurons
Book
12/2009
1st Edition
Springer
€160.49
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Content
Profiling the microRNAs.- The Wide Variety of miRNA Expression Profiles in the Developing and Mature CNS.- Interactions between microRNAs and Transcription Factors in the Development and Function of the Nervous System.- A microRNA Feedback Circuit in Midbrain Dopamine Neurons.- Fine-tuning mRNA Translation at Synapses with microRNAs.- Neuronal P-bodies and Transport of microRNA-Repressed mRNAs.- Crosstalk between microRNA and Epigenetic Regulation in Stem Cells.- microRNAs in CNS Development and Neurodegeneration: Insights from Drosophila Genetics.- Drosophila as a Model for Neurodegenerative Disease: Roles of RNA Pathways in Pathogenesis.- microRNAs in Sporadic Alzheimer's Disease and Related Dementias.- microRNA Dysregulation in Psychiatric Disorders.
