Neuroendocrine Disorders in Children
Description
Impairments in the interaction between the central nervous system and the endocrine system can lead to a number of disorders in children. These include type 1 diabetes, growth disorders, adrenal thyroid and pituitary problems, Addison's disease and Cushing syndrome, among others.
Neuroendocrine Disorders in Children provides a comprehensive examination of paediatric and adolescent disorders focusing on the basic science and its clinical relevance. Complex issues are discussed in an easy-to-follow manner and the latest developments in the area are reviewed.
This volume will become invaluable reading for paediatric endocrinologists, paediatric and adult neurologists and trainee paediatricians.
Sections in the book cover
.The GH-IGF1 axis and the brain
.The thyroid axis and the brain
.Regulation of appetite and weight
.Effects of treatment of cancer on the neuroendocrine system
.Adrenal disorders and the brain
.Neuroendocrinology and the reproductive axis
.Neurological complications of diabetes mellitus
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Content
- Cover
- Title
- Copyright
- Contents
- Authors' Appointments
- Foreword
- Preface
- Section 1: The Gh-Igf1 Axis and The Brain
- 1. Neuroendocrine Regulation of Growth Hormone Secretion - Peter C Hindmarsh and Iain CAF Robinson
- 2. Disorders of The Hypothalamo-Pituitary-Somatotroph Axis Leading to Growth Failure - Kyriaki S Alatzoglou and Mehul T Dattani
- 3. The Effect of Growth Hormone on The Brain - Fred Nyberg, Alfhild Grönbladh, Erika Brolin, Anna Jonsson, Jenny Johansson and Mathias Hallberg
- 4. Impact of Disorders of The Growth Hormone-Igf-1 Axis on Neurological Function - Emma A Webb and Mehul T Dattani
- 5. Neuroendocrine Disorders of Salt and Water Balance - Joseph A Majzoub
- Section 2: The Thyroid Axis and The Brain
- 6. The Hypothalamic-Pituitary-Thyroid Axis: Anatomy and Physiology - Mary-Jane Brassill, Apostolos I Gogakos, John G Logan, Julian A Waung and Graham R Williams
- 7. Disorders of The Hypothalamo-Pituitary-Thyroid Axis - Tim Cheetham and Ramesh Srinivasan
- 8. Impact of Thyroid Disorders on Neurological Function - Joanne F Rovet
- Section 3: Regulation of Appetite and Weight
- 9. The Role of The Hypothalamus in Normal Weight Regulation - Simon M Luckman
- 10. Genetic Childhood Obesity Syndromes - I Sadaf Farooqi
- 11. Treatment of Obesity - Terry Segal and Bhavni Shah
- Section 4: Effects of The Treatment of Cancer on The Neuroendocrine System
- 12. Late Effects of Cancer and Its Treatments on The Neuroendocrine System - Wassim Chemaitilly and Charles A Sklar
- 13. Craniopharyngioma - Hoong-Wei Gan, Juan Pedro Martinez-Barbera, Helen A Spoudeas and Mehul T Dattani
- Section 5: Adrenal Disorders and The Brain
- 14. The Hypothalamo-Pituitary-Adrenal Axis and Its Regulation - Elizabeth Baranowski, Tulay Guran and Nils Krone
- 15. The Effect of Stress on The Hypothalamic-Pituitary-Adrenal Axis: An Update - Evangelia Charmandari and George P Chrousos
- 16. Adrenoleukodystrophy: Neurological Aspects - Patrick Aubourg
- 17. Cushing Disease: Diagnosis and Management - Helen L Storr and Martin O Savage
- Section 6: Neuroendocrinology and The Reproductive Axis
- 18. The Hypothalamic-Pituitary-Gonadal Axis - Pierre-Marc G Bouloux
- 19. The Inherited Basis of Hypogonadotropic Hypogonadism - Pierre-Marc G Bouloux
- 20. Precocious Puberty - Jean-Claude Carel, Laetitia Martinerie, Dominique Simon, Delphine Zenaty, Nicolas de Roux and Juliane Léger
- 21. Psychological and Behavioural Consequences of Gonadal Hormone Abnormality During Early Development - Melissa Hines
- Section 7: Diabetes and Insulin Signalling
- 22. Diabetes and The Developing Brain - Fergus J Cameron, Elisabeth A Northam and Terrie E Inder
- 23. Central Actions of Insulin - Benjamin G Challis and Robert K Semple
- Index
- Color Plate Section
