Understanding Cancer Biology
Genetics, Molecular Biology, and Cellular Signaling Pathways
Taylor & Francis (Publisher)
Will be published approx. on 11. August 2026
740 pages
E-Book
978-1-040-93411-1 (ISBN)
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Description
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This book provides a comprehensive and current perspective on cancer research. It covers cancer biology through seven well-laid-out sections. Section I describes normal cell division, cellular homeostasis, and malignant cell transformation. Genetics, cancer epigenetics, cell cycle checkpoints, and growth-regulatory gene expression are covered in Section II. Section III discusses carcinogens, which cause cancer. Section IV describes molecular changes in cancer genes and signaling pathways, which are also employed to develop precise cancer diagnostics and treatments. Section V discusses tumor initiation, progression, metastasis, and therapeutic response, which depend on tumor cell-microenvironment interactions and their impact on disease. Section VI covers cancer diagnosis and newer, more targeted treatment. The post-genomic age and molecular methods have boosted cancer research. Section VII shows how molecular profiling, proteomics, metabolomics, and system biology may help comprehend this complex disease. This section also discusses the microbiome's role in cancer progression and therapeutic possibilities.
More details
Language
English
Place of publication
London
United Kingdom
Target group
College/higher education
Professional and scholarly
Product notice
Reflowable
Illustrations
46 Tables, black and white; 86 Line drawings, color; 44 Line drawings, black and white; 86 Illustrations, color; 44 Illustrations, black and white
ISBN-13
978-1-040-93411-1 (9781040934111)
Copyright in bibliographic data is held by Nielsen Book Services Limited or its licensors: all rights reserved.
Schweitzer Classification
Other editions
Additional editions

Sonal Datta | Anil K. Sharma | Reena V. Saini
Understanding Cancer Biology
Genetics, Molecular Biology, and Cellular Signaling Pathways
Book
approx. 08/2026
1st Edition
Jenny Stanford Publishing
€475.50
Not yet published
Persons
Sonal Datta is a cancer biologist and protein engineer, currently a Professor in the Department of Bio-Sciences and Technology at Maharishi Markandeshwar (Deemed to be University) [MM(DU)], Mullana, Ambala, Haryana, India. She received her PhD from the Dr. B. R. Ambedkar Center for Biomedical Research at the University of Delhi, India. She was a visiting scientist at the Evanston Northwestern Healthcare Research Institute, Evanston, USA, and the University of Alabama at Birmingham, USA. Dr. Datta has published high-impact articles and book chapters. She has developed novel biosimilar and biobetter therapeutics.
Anil K. Sharma is a Professor and Dean at Amity University, Mohali, Punjab, India. He received his PhD from PGIMER, Panjab University, India. He was a visiting scientist at the University of Illinois, Chicago, USA. He has over 300 publications, an h-index of 45, 17 books, 17 patents, and numerous awards. Dr. Sharma has guided 12 PhD scholars and has been featured in Stanford University's list of the top 2% of highly cited researchers globally.
Reena V. Saini is a cancer biologist working as a Professor in the Department of Bio-Sciences and Technology at MM(DU). She received her PhD from Dr. B. R. Ambedkar Center for Biomedical Research at the University of Delhi, India, and was a postdoctoral fellow at the NCI, National Institutes of Health, USA. She has published over 120 articles in reputed journals and book chapters.
Adesh K. Saini is the Director of the Research and Development Cell and a Professor in the Department of Bio-Sciences and Technology at MM(DU). He received his PhD from the Dr. B. R. Ambedkar Center for Biomedical Research at the University of Delhi, India, and was a postdoctoral fellow at the NICHD, National Institutes of Health, USA. He has published over 150 articles and 70 patents. He is on Stanford University's list of the top 2% of highly cited researchers globally with an h-Index of 50.
Anil K. Sharma is a Professor and Dean at Amity University, Mohali, Punjab, India. He received his PhD from PGIMER, Panjab University, India. He was a visiting scientist at the University of Illinois, Chicago, USA. He has over 300 publications, an h-index of 45, 17 books, 17 patents, and numerous awards. Dr. Sharma has guided 12 PhD scholars and has been featured in Stanford University's list of the top 2% of highly cited researchers globally.
Reena V. Saini is a cancer biologist working as a Professor in the Department of Bio-Sciences and Technology at MM(DU). She received her PhD from Dr. B. R. Ambedkar Center for Biomedical Research at the University of Delhi, India, and was a postdoctoral fellow at the NCI, National Institutes of Health, USA. She has published over 120 articles in reputed journals and book chapters.
Adesh K. Saini is the Director of the Research and Development Cell and a Professor in the Department of Bio-Sciences and Technology at MM(DU). He received his PhD from the Dr. B. R. Ambedkar Center for Biomedical Research at the University of Delhi, India, and was a postdoctoral fellow at the NICHD, National Institutes of Health, USA. He has published over 150 articles and 70 patents. He is on Stanford University's list of the top 2% of highly cited researchers globally with an h-Index of 50.
Content
1. Cell Division in Multicellular Organisms 2. Cell Senescence, Immortalization and Cancer Progression 3. DNA Repair and Genome Integrity 4. Genetic Instability and Cancer 5. Epigenetics and Cancer 6. The Role of Oncogenes in Cancer Initiation and Progression: Mechanisms and Therapeutic Implications 7. Viral Carcinogenesis 8. Chemical Carcinogenesis 9. Radiation as a Carcinogen 10. Understanding Cancer and Its Broad Classification 11. The Role of Growth Factors and Cytokines in Cancer: Insights Into Cell Signaling Pathways 12. Apoptosis in Cancer: Current Paradigms and Future Relevance 13. The Role of Autophagy in Cancer 14. Role of Telomerase and Immortalization 15. Deciphering the Dynamics of Hypoxia, Cancer and Antioxidant Defense Mechanism 16. Metastasis, Invasion, and Tumor Dormancy 17. Cancer Stem Cells: Therapeutic and Regenerative Innovations 18. Cellular Immunity in Cancer: Role in Protection and Progression 19. Tumor Microenvironment: Its Role in Cancer Progression and Metastasis 20. Angiogenesis and Cancer Biology: A Promising Drug Target 21. Diagnosis of Cancer 22. Surgical Interventions in Cancer 23. Chemotherapy 24. The Biological E?ects of Chemotherapy on Cancer Cells 25. Basics of Radiotherapy 26. The Biological E?ect of Radiotherapy on Cancer Cells 27. Immunotherapy and Other Emerging Treatment Options 28. Newer Antibodies to Treat Cancer 29. Molecular Profiling in Cancer Research and Personalized Medicine 30. Proteomics and Metabolomics Application in Cancer 31. Cancer Systems Biology: From Molecular Profiles to Pathways, Signaling Networks, and Therapeutic Targets 32. Emerging Role of the Microbiome in Cancer Progression and Therapeutic Implications
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