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Synapse, Neuron, Brain, the third and last volume in the series Medical Physics, focuses on neurons and their interactions. Comprised of seven chapters regarding the brain's synapses and nerves, this volume concludes through the presentation of medical physics and its applications. An introductory chapter of this volume provides the necessary basic concepts and theories needed in the understanding of the book. This is followed by a discussion on the brain and its interconnections with the spinal cord. Chapter 3 focuses on the importance of evoked potentials as a diagnostic tool for the sensory organ and the neural processing of the stimuli. Chemical and electrical properties of synapses are also given emphasis. Other topics covered in this volume include the rall theory and neuronal integration; membrane noise at synaptic junctions; and new techniques on brain studies (autoradiography, positron annihilation, and nuclear magnetic resonance). As with the other volumes, this also caters to persons in various disciplines such as medicine, physiology, physics, and biology.
Language
Place of publication
Publishing group
Elsevier Science & Techn.
ISBN-13
978-0-323-15464-2 (9780323154642)
Schweitzer Classification
PrefaceAcknowledgmentsContents of Previous VolumesChapter 1 Introduction ReferencesChapter 2 The Evolution and Morphology of the Brain Introduction Origin of the Two-Sided Brain Origin of Vertebrates Development of the Brain Architecture of the Human Brain The Triune Brain Cephalization of the Species Brain Asymmetry Left-Handedness Survival Value of Cerebral Dominance Arrangement of Cortical Neurons ReferencesChapter 3 Electrical Properties of the Brain; EEG and Evoked Potentials Introduction Electroencephalography Computer Diagnosis of Electroencephalograms Cellular Origins of Electroencephalogram Brain Waves Evoked Potentials Visual Evoked Potentials Diagnostics of Children Using Visual Evoked Potentials Diagnosis of Optic Neuritis Using Visual Evoked Potentials Origin of Evoked Potentials Auditory Evoked Potentials Evoked Potentials as a Measure of Mental Chronometry ReferencesChapter 4 Chemical and Electrical Properties of Synapses Introduction Kinds of Synaptic Connections Chemical Synapses Electrical Synapses Properties of Postsynaptic Potentials and Currents at Chemical Synapses Presynaptic Properties of Chemical Synapses Exocytosis A Molecular Model of Postsynaptic Responses Drug Action at Synaptic Receptors Central-Nervous-System Neurons and Drug Effects Common Diseases Associated with Synaptic Function ReferencesChapter 5 Neuronal Integration and Rall Theory Introduction Effects of Environment and Malnutrition on Dendrite Growth Dendrite Electrotonus and the Linear Cable Equation Special Solutions to the Cable Equation Boundary Conditions at Dendritic Branch Points Equivalent Cylinder Approximation Properties of Somatic Potentials with Dendritic Synaptic Inputs Compartmental Model Shape and Time Behavior of Soma Potentials Transient Passive Membrane Responses ReferencesChapter 6 Analysis of Membrane Noise at Synaptic Junctions Introduction Analysis of Random Signals Autocorrelation Function Power Spectrum Determination of Power Spectrum (Spectral Density Function) Thermal Noise Shot Noise Flicker Noise Conductance Noise Current Noise at the End Plate Frequency Composition Channels at the Neuromuscular Junction Effect of Pore Structure Single-Channel Events Conductance Fluctuations in the Presence of Local Anesthetics ReferencesChapter 7 New Techniques of Brain Studies: Autoradiography, Positron Annihilation, and NuclearMagnetic Resonance Introduction Autoradiographic Determination of Regional Brain Metabolism Dynamic Radiographic Studies of Brain Metabolism Coincidence Counting of Positron Annihilation Design Considerations of Positron Annihilation Positron-Emission Measurement of Brain Metabolism General Aspects of Nuclear Magnetic Resonance Spinning Tops Larmor Precession Nuclear Moments Effect of a Radio-Frequency Field Population and Relaxation Spin-Spin Relaxation Spin-Lattice Relaxation Spin-Echo Technique Nuclear Magnetic Resonance Imaging Chemical Shifts Intracellular pH Measurement by 31P Nuclear Magnetic Resonance ReferencesAppendix A Open-Channel Distribution FunctionAppendix B Rall's Branching RuleAppendix C Proof of the Equivalent Cylinder ApproximationAppendix D Solution to the Cable Equation for a Cylinder with Sealed EndsAppendix E Autocorrelation FunctionAppendix F Fourier CoefficientsAppendix G Fourier TransformsAppendix H Sampling TheoremAppendix I One-Dimensional Random WalkAppendix J End-Plate Current Spectral FunctionAppendix K Intracellular Trapping of 2-Deoxy-D-glucoseAppendix L Statistical Properties of Single-Channel EventsIndex