Current Topics in Membranes and Transport
Protein-membrane interactions
Academic Press
Published on 10. August 1990
181 pages
978-0-08-058507-9 (ISBN)
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Current Topics in Membranes and Transport
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Felix Bronner | A. Kleinzeller
Current Topics in Membranes and Transport: Protein Membrane Interactions v. 36
Book
06/1990
Academic Press
€69.33
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Content
- Front Cover
- Protein-Membrane Interactions
- Copyright Page
- Contents
- Contributors
- Preface
- Yale Membrane Transport Processes Volumes
- PART I: PROTEIN INSERTION INTO AND ACROSS MEMBRANES
- Chapter 1. Mitochondrial Protein Import: Specific Recognition and Membrane Insertion of Precursor Proteins
- I. Introduction
- II. Receptor Proteins on the Mitochondrial Surface
- III. The "General Insertion Protein"
- IV. Role of Receptors and General Insertion Protein
- V. Summary and Perspectives
- References
- Chapter 2. An Enzymological Approach to Membrane Assembly and Protein Secretion
- Text
- Chapter 3. Protein Translocation in Yeast
- I. Introduction
- II. Yeast as a Model System
- III. The Importance of Preprotein Conformation
- IV. Binding to the Membrane and Translocation Are Separable Events
- V. Analysis of ptl1-A Translocation Mutant
- References
- PART II: STRUCTURE OF PROTEINS IN THE MEMBRANE
- Chapter 4. Architectural Editing: Regulating the Surface Expression of the Multicomponent T-Cell Antigen Receptor
- I. Introduction
- II. Structure and Composition of the T-Cell Antigen Receptor
- III. Subunit Interactions within the T-Cell Receptor
- IV. Stoichiometry within the Complex
- V. Assembly of the T-Cell Receptor Complex
- VI. Fate of Newly Synthesized T-Cell Receptor Chains
- VII. Summary
- References
- Chapter 5. The Photosynthetic Reaction Center from the Purple Bacterium Rhodopseudomonas viridis: Aspects of Membrane Protein Structure
- I. Introduction
- II. Results and Discussion
- III. Conclusions
- References
- Chapter 6. Bacteriorhodopsin Folding in Membranes: A Two-Stage Process
- I. Introduction
- II. Bacteriorhodopsin
- III. Bacteriorhodopsin Fragments Contain Stable Transbilayer Helices
- IV. Links and Retinal Are Not Required for Folding
- V. Polar Interactions in Helix-Helix Associations
- VI. Packing Effects
- VII. Summary
- References
- PART III: PROTEIN MOBILITY IN MEMBRANES
- Chapter 7. Molecular Associations and Membrane Domains
- I. Models of Membrane Organization
- II. The Study of Large-Scale Molecular Mobility in Cell Surface Membranes
- III. A Basis for the Organization of Morphologically Polarized Cell Surfaces
- IV. Concluding Remarks
- References
- Chapter 8. Actin-Membrane Interactions in Eukaryotic Mammalian Cells
- I. The Actin System and Membrane Function
- II. The Erythrocyte Cytoskeleton: Paradigm or Distraction in Approaching the Interaction between the Eukaryote Plasma Membrane and Actin System?
- III. The Actin System in Membrane Stabilization and Retraction
- IV. The Actin System in Membrane Propulsion
- V. The Actin System and Membrane Propulsion and Retraction
- References
- Chapter 9. Biogenesis and Cell Surface Distribution of Acetylcholine Receptors Stably Expressed in Fibroblasts
- I. Introduction
- II. Acetylcholine Receptor-Fibroblast Cell Lines
- III. Properties of Acetylcholine Receptors Expressed in Acetylcholine Receptor-Fibroblast Cells
- IV. Properties of Individually Expressed Subunits
- V. Posttranslational Modifications
- VI. Conclusions
- References
- Chapter 10. Control of Organelle Movements and Endoplasmic Reticulum Extension Powered by Kinesin and Cytoplasmic Dynein
- I. Introduction
- II. Membranous Organelle Transport on Microtubules
- III. Interaction of Motors with Organelles to Produce Motility
- References
- PART IV: SIGNALING AND COMMUNICATION
- Chapter 11. G Protein-Coupled Receptors: Structure and Function of Signal-Transducing Proteins
- I. Introduction
- II. Mechanism of G-Protein Activation by Agonist-Liganded Receptors
- III. General Structure of G Protein-Coupled Receptors
- IV. Structure of the Ligand-Binding Domain
- V. Structure of the G Protein-Binding Domain
- VI. Receptor-Mimetic Peptides as Models for the G Protein-Binding Domain
- References
- Chapter 12. Mechano-Sensitive Ion Channels in Microbes and the Early Evolutionary Origin of Solvent Sensing
- I. Introduction
- II. A Stretch-Activated Ion Channel of Escherichia coli
- III. A Stretch-Activated Ion Channel in Yeast
- IV. Touch Receptors and Channels of Paramecium
- V. Mechano-Sensitive Channels and the Concept of Solvent Senses
- References
- Chapter 13. Selection of an aß T-Cell Antigen Receptor in Vivo and Expression in Vitro in a Soluble Form
- I. Introduction
- II. Positive Selection
- III. Negative Selection
- IV. Soluble T-cell Receptor Heterodimers
- References
- Chapter 14. Perforin and the Mechanism of Lymphocyte-Mediated Cytolysis
- I. Introduction
- II. Physicochemical and Functional Properties of Perforin
- III. Sequence of Murine and Human Perforin
- IV. Homology of Perforin to Complement Proteins: The Perforin Family
- V. Lack of Homologous Restriction of Perforin
- VI. Expression of Perforin mRNA in Vitro and in Vivo
- VII. The Contribution of Membrane Pores to DNA Degradation
- VIII. Conclusions
- References
- Note Added in Proof
- Index
